OKAZAWA Hidehiko

FacultyBiomedical Imaging Research Center
Teacher OrganizationBiomedical Imaging Research Center
Education and
 Research Organization
Biomedical Imaging Research Center
PositionProfessor
Last Updated: 19/07/23 18:49

Researcher Profile & Settings

Name

    OKAZAWA Hidehiko

Affiliation

  •  Biomedical Imaging Research Center Professor

Education

  • Apr. 1992Mar. 1996Kyoto University 内科系
  • Apr. 1982Mar. 1988Kyoto University School of Medicine

Academic & Professional Experience

  • May 2010Biomedical Imaging Research Center Director
  • Jan. 2006Biomedical Imaging Research Institute, University of Fukui Professor
  • Jan. 2003Sep. 2006Biomedical Imaging Research Institute, University of Fukui Associate Professor
  • Jan. 1999Dec. 2002Research Institute, Shiga Medical Center Researcher
  • Jun. 1996Dec. 1998Montreal Neurological Institute, McGill University Postdoctoral fellow
  • Apr. 1996May 1996Department of Nuclear Medicine, Kyoto University Hospital Clinical staff
  • Apr. 1992Mar. 1996Kyoto University, Graduate School of Medicine Graduate School Student
  • Apr. 1989Mar. 1992Shiga Medical Center, Department of Radiology Physician
  • Jun. 1988Mar. 1989Kyoto University Hospital, Department of Radiology and Nuclear Medicine Resident

Association Memberships

    Japanese Society for Molecular Imaging trustee,The Japan Neuroscience Society member,The Japanese Council of Nuclear Neuroimaging other,The Japan Stroke Society member of editorial board,Japanese Society of Nuclear Medicine trustee,American Academy of Neurology member,European Association of Nuclear Medicine member,International Society of Cerebral Blood Flow and Metabolism member,Society of Nuclear Medicine member,Japan Radiological Society member,

Overseas travel history

  • カナダ Montreal神経学研究所、McGill大学 Jun.  1996- Dec. 1998

Research Activities

Published Papers

  • Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation.
    Okazawa H, Higashino Y, Tsujikawa T, Arishima H, Mori T, Kiyono Y, Kimura H, Kikuta K.
    Eur J Radiol 105 102-109 Jun.  2018 Refereed
  • CT-based attenuation correction and resolution compensation for I-123 IMP brain SPECT normal database: a multicenter phantom study
    Inui Y, Ichihara T, Uno M, Ishiguro M, Ito K, Kato K, Sakuma H, Okazawa H, Toyama H
    Ann Nucl Med 32(5) 311-318 Jun.  2018 Refereed
  • PET probe detecting non-small cell lung cancer susceptible to epidermal growth factor receptor tyrosine kinase inhibitor therapy
    Makino A, Miyazaki A, Tomoike A, Kimura H, Arimitsu K, Hirata M, Ohmomo Y, Nishii R, Okazawa H, Kiyono Y, Ono M, Saji H
    Bioorg Med Chem 26(8) 1609-1613 May  2018 Refereed
  • Role of PET/MRI in oral cavity and oropharyngeal cancers based on the 8th edition of the AJCC cancer staging system: a pictorial essay
    Tsujikawa T, Narita N, Kanno M, Takabayashi T, Fujieda S, Okazawa H
    Ann Nucl Med 32(4) 239-249 May  2018 Refereed
  • Selected PET radiomic features remain the same
    Tsujikawa T, Tsuyoshi H, Kanno M, Yamada S, Kobayashi M, Narita N, Kimura H, Fujieda S, Yoshida Y, Okazawa H
    Oncotarget 9(29) 20734-20746 Apr.  2018 Refereed
  • Self-Face Recognition Begins to Share Active Region in Right Inferior Parietal Lobule with Proprioceptive Illusion During Adolescence
    Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E
    Cereb Cortex 28(4) 1532-1548 Apr.  2018 Refereed
  • 18F-FDG PET radiomics approaches: comparing and clustering features in cervical cancer
    Tsujikawa T, Rahman T, Yamamoto M, Yamada S, Tsuyoshi H, Kiyono Y, Kimura H, Yoshida Y, Okazawa H
    Ann Nucl Med 31(9) 678-685 Nov.  2017 Refereed
  • Development of right-hemispheric dominance of inferior parietal lobule in proprioceptive illusion task
    Naito E, Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M
    Cereb Cortex 27(11) 5385-5397 Nov.  2017 Refereed
  • Assessment of intratumor heterogeneity in mesenchymal uterine tumor by an (18)F-FDG PET/CT texture analysis
    Tsujikawa T, Yamamoto M, Shono K, Yamada S, Tsuyoshi H, Kiyono Y, Kimura H, Okazawa H, Yoshida Y
    Ann Nucl Med 31(10) 752-757 Sep.  2017 Refereed
  • Precise evaluation of striatal oxidative stress corrected for severity of dopaminergic neuronal degeneration in patients with parkinson's disease: A study with 62Cu-ATSM PET and 123I-FP-CIT SPECT
    Neishi H, Ikawa M, Okazawa H, Tsujikawa T, Arishima H, Kikuta KI, Yoneda M
    Eur Neurol 78(3-4) 161-168 Aug.  2017 Refereed
  • Highly sensitive telomerase assay insusceptible to telomerase and polymerase chain reaction inhibitors for cervical cancer screening using scraped cells
    Yaku H, Yoshida Y, Okazawa H, Kiyono Y, Fujita Y, Miyoshi D
    Anal Chem 89(13) 6948-6953 Jul.  2017 Refereed
  • A novel diagnostic strategy using 16α-[18F]-fluoro-17-β-estradiol (18F-FES) PET/MRI to achieve complete resection of intravenous leiomyomatosis in reproductive-age women
    Chino Y, Tsuyoshi H, Tsujikawa T, Okazawa H, Yoshida Y
    Clin Nucl Med 42(7) e335-e336 Jul.  2017 Refereed
  • Estimation of arterial input by a noninvasive image derived method in brain H215O PET study confirmation of arterial location using MR angiography
    Islam MM, Tsujikawa T, Mori T, Kiyono Y, Okazawa H
    Phys Med Biol 62(11) 4514-4524 Jun.  2017 Refereed
  • Age-dependent atypicalities in body- and face-sensitive activation of the EBA and FFA in individuals with ASD
    Okamoto Y, Kosaka H, Kitada R, Seki A, Tanabe HC, Hayashi MJ, Kochiyama T, Saito DN, Yanaka HT, Munesue T, Ishitobi M, Omori M, Wada Y, Okazawa H, Koeda T, Sadato N
    Neurosci Res 119 38-52 Jun.  2017 Refereed
  • Ethnic differences in COMT genetic effects on striatal grey matter alterations associated with childhood ADHD: A voxel-based morphometry study in a Japanese sample
    Shimada K, Fujisawa TX, Takiguchi S, Naruse H, Kosaka H, Okazawa H, Tomoda A
    World J Biol Psychiatry 18(4) 322-328 Jun.  2017 Refereed
  • Pixel-by-pixel precise delay correction for measurement of cerebral hemodynamic parameters in H2(15)O PET study
    Islam MM, Tsujikawa T, Mori T, Kiyono Y, Okazawa H
    Ann Nucl Med 31(4) 283-294 May  2017 Refereed
    OBJECTIVE:A new method of delay time estimation was proposed to measure precise cerebral blood flow (CBF) and arterial-to-capillary blood volume (V 0) using (15)O-water PET.;METHODS:Nineteen patients with unilateral arterial stenoocclusive lesions were studied to evaluate hemodynamic status before treatment. The delay time of each pixel was calculated using least squares fitting with an arterial blood input curve adjusted to the internal carotid artery counts at the skull base. Pixel-by-pixel delay estimation provided a delay map image that could be used for precise calculation of CBF and V 0 using a one-tissue compartment model, and the values from this method were compared with those from the slice-by-slice correction method.;RESULTS:The affected side showed a longer delay time than the contralateral cerebral hemisphere. Although the mean cortical CBF values were not different between the two methods, the slice-by-slice delay correction overestimatedツ?CBF in the hypo perfused area. The scatter plot of V 0 pixel values showed significant difference between the two correction methods where the slice-by-slice delay correction significantly overestimated V 0 in the whole brain (P窶?<窶?0.05).;CONCLUSION:Pixel-by-pixel delay correction provides delay images as well as better estimation of CBF and V 0, thus offering useful and beneficial information for the treatment of cerebrovascular disease.
  • Self-face recognition shares brain regions active during proprioceptive illusion in the right inferior fronto-parietal superior longitudinal fasciculus III network
    Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E
    Neuroscience 348 288-301 Apr.  2017 Refereed
    :Proprioception is somatic sensation that allows us to sense and recognize position, posture, and their changes in our body parts. It pertains directly to oneself and may contribute to bodily awareness. Likewise, one's face is a symbol of oneself, so that visual self-face recognition directly contributes to the awareness of self as distinct from others. Recently, we showed that right-hemispheric dominant activity in the inferior fronto-parietal cortices, which are connected by the inferior branch of the superior longitudinal fasciculus (SLF III), is associated with proprioceptive illusion (awareness), in concert with sensorimotor activity. Herein, we tested the hypothesis that visual self-face recognition shares brain regions active during proprioceptive illusion in the right inferior fronto-parietal SLF III network. We scanned brain activity using functional magnetic resonance imaging while twenty-two right-handed healthy adults performed two tasks. One was a proprioceptive illusion task, where blindfolded participants experienced a proprioceptive illusion of right hand movement. The other was a visual self-face recognition task, where the participants judged whether an observed face was their own. We examined whether the self-face recognition and the proprioceptive illusion commonly activated the inferior fronto-parietal cortices connected by the SLF III in a right-hemispheric dominant manner. Despite the difference in sensory modality and in the body parts involved in the two tasks, both tasks activated the right inferior fronto-parietal cortices, which are likely connected by the SLF III, in a right-side dominant manner. Here we discuss possible roles for right inferior fronto-parietal activity in bodily awareness and self-awareness.
  • 18F-FDG/18F-FES standardized uptake value ratio determined using PET predicts prognosis in uterine sarcoma
    Yamamoto M, Tsujikawa T, Yamada S, Kurokawa T, Shinagawa A, Chino Y, Mori T, Kiyono Y, Okazawa H, Yoshida Y
    Oncotarget 8(14) 22581-22589 Apr.  2017 Refereed
    :We investigated whether 16α-[18F]-fluoro-17β-estradiol (18F-FES) and 18F-fluoro-deoxyglucose (FDG) uptake measured using positron emission tomography (PET) predicted prognosis in 18 patients with different histological subtypes of uterine sarcoma. Standardized uptake values (SUVs) and 18F-FDG/18F-FES SUV ratios were determined, and their correlations with progression-free (PFS) and overall survival (OS) were examined. Ten patients died from local recurrence or metastasis, and one more experienced recurrence, during the at least 36-month follow-up period. Patients with higher 18F-FDG SUVs (> 5.5) had worse OS (p = 0.007) and tended toward worse PFS (p = 0.11), while patients with lower 18F-FES SUVs (竕、 1.5) had worse PFS (p = 0.03) and tended toward worse OS (p = 0.19). Patients with 18F-FDG/18F-FES ratios > 2.6 had worse PFS (p = 0.009) and OS (p = 0.005). The 5-year PFS and OS rates were 75% and 88% for patients with lower ratios, but were only 10% and 20% for those with higher ratios. These results suggest that pretreatment tumor 18F-FDG/18F-FES ratio is useful for predicting the prognosis of uterine sarcoma patients.
  • Cerebral hyperperfusion syndrome resulting in subarachnoid hemorrhage after carotid artery stenting.
    Isozaki M, Arai Y, Higashino Y, Okazawa H, Kikuta K
    Ann Nucl Med 30(9) 669-674 Nov.  2016 Refereed
    :A 64-year-old, right-handed man underwent endovascular treatment for internal carotid artery stenosis after experiencing a left-hemispheric transient ischemic attack. (15)O-gas and H 2(15) O positron emission tomography revealed slightly reduced cerebral blood flow (CBF), elevated cerebral blood volume, and severely reduced cerebral vasoreactivity in the ipsilateral hemisphere as determined by an acetazolamide challenge test. The patient underwent left carotid artery stenting (CAS) via a prefemoral approach under local anesthesia without any complications. Follow-up examinations performed 20ツ?h postoperatively showed subarachnoid hemorrhage (SAH) and cerebral hyperperfusion syndrome (CHS) in the left frontal lobe. Although it is a relatively rare phenomenon, SAH resulting from CHS was determined to be specifically caused by CAS. In this case, the causes of SAH may have been related to multiple factors including increased regional CBF, loss of cerebrovascular autoregulation, contrast agent-mediated disruption of major cerebral vessels, and strong antiplatelet therapy.
  • Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial
    Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa TX, Tanaka S, Arai S, Asano M, Saito DN, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y.
    Transl Psychiatry 6(8) e872 Aug.  2016 Refereed
  • Impaired myocardial microcirculation in the flow-glucose metabolism mismatch regions in revascularized acute myocardial infarction.
    Fukuoka Y, Nakano A, Tama N, Hasegawa K, Ikeda H, Morishita T, Ishida K, Kaseno K, Amaya N, Uzui H, Okazawa H, Tada H
    J Nucl Cardiol Jun.  2016 Refereed
    BACKGROUND:In successfully revascularized acute myocardial infarction (AMI), microvascular function in a myocardial flow-glucose metabolism mismatch pattern has not been reported. We aimed to elucidate myocardial flow reserve (MFR) and myocardial viability in mismatch segments.;METHODS:(18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) and adenosine stress (13)N-ammonia PET were performed in eighteen AMI patients to evaluate myocardial glucose metabolism, myocardial blood flow (MBF), and MFR. Infarct segments were classified into 3 groups: normal (preserved resting MBF), mismatch (preserved FDG uptake but reduced resting MBF), and match (reduced FDG uptake and resting MBF). Regional wall motion score (WMS) was assessed immediately after reperfusion and recovery periods.;RESULTS:MFR in the mismatch group was significantly lower than that in non-infarct-related segments (1.655ツ?±ツ?0.516 vs 2.282ツ?±ツ?0.629, Pツ?<ツ?.01) and similar to that in the match group (1.635ツ?±ツ?0.528, Pツ?=ツ?.999). WMS in the mismatch group was significantly improved (3.07ツ?±ツ?0.48 vs 2.07ツ?±ツ?1.14, Pツ?=ツ?.003); however, in recovery periods, WMS in the mismatch group was significantly higher than that in the normal group (1.05ツ?±ツ?1.04, Pツ?<ツ?.01).;CONCLUSIONS:In successfully revascularized AMI, microvascular function is impaired despite preserved myocardial glucose metabolism in mismatch segments.
  • Arterial transit time mapping obtained by pulsed continuous 3D ASL imaging with multiple post-label delay acquisitions: Comparative study with PET-CBF in patients with chronic occlusive cerebrovascular disease.
    Tsujikawa T, Kimura H, Matsuda T, Fujiwara Y, Isozaki M, Kikuta K, Okazawa H.
    PLoS ONE 11(6) e0156005 Jun.  2016 Refereed
  • Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders.
    Morita T, Kosaka H, Saito DN, Fujii T, Ishitobi M, Munesue T, Inohara K, Okazawa H, Kakigi R, Sadato N.
    Res Autism Spectr Disord 26 16-32 Jun.  2016 Refereed
  • Assessment of the tumor redox status in head and neck cancer by 62Cu-ATSM PET.
    Tsujikawa T, Asahi S, Oh M, Sato Y, Narita N, Makino A, Kiyono Y, Tsuchida T, Kimura H, Fujieda S, Okazawa H.
    PLoS ONE 11(5) e0155635 May  2016 Refereed
    PURPOSE:Tumor redox is an important factor for cancer progression, resistance to treatments, and a poor prognosis. The aim of the present study was to define tumor redox (over-reduction) using 62Cu-diacetyl-bis(N4-methylthiosemicarbazone) (62Cu-ATSM) PET and compare its prognostic potential in head and neck cancer (HNC) with that of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG).;METHODS:Thirty HNC patients (stage II-IV) underwent pretreatment 62Cu-ATSM and 18F-FDG PET scans. Maximum standardized uptake values (SUVATSM and SUVFDG) and tumor-to-muscle activity concentration ratios (TMRATSM and TMRFDG) were measured. Reductive-tumor-volume (RTV) was then determined at four thresholds (40%, 50%, 60%, and 70% SUVATSM), and total-lesion-reduction (TLR) was calculated as the product of the mean SUV and RTV for 62Cu-ATSM. In 18F-FDG, metabolic-tumor-volume (MTV) and total-lesion-glycolysis (TLG) were obtained at a threshold of 40%. A ROC analysis was performed to determine % thresholds for RTV and TLR showing the best predictive performance, and these were then used to determine the optimal cut-off values to stratify patients for each parameter. Progression-free-survival (PFS) and cause-specific-survival (CSS) were evaluated by the Kaplan-Meier method.;RESULTS:The means ± standard deviations of PFS and CSS periods were 16.4±13.4 and 19.2±12.4 months, respectively. A ROC analysis determined that the 70% SUVATSM threshold for RTV and TLR was the best for predicting disease progression and cancer death. Optimal cut-offs for each index were SUVATSM = 3.6, SUVFDG = 7.9, TMRATSM = 3.2, TMRFDG = 5.6, RTV = 2.9, MTV = 8.1, TLR = 14.0, and TLG = 36.5. When the cut-offs for TMRATSM and TLR were set as described above in 62Cu-ATSM PET, patients with higher TMRATSM (p = 0.03) and greater TLR (p = 0.02) showed significantly worse PFS, while patients with greater TLR had significantly worse CSS (p = 0.02). Only MTV in 18F-FDG PET predicted differences in PSF and CSS (p = 0.03 and p = 0.03, respectively).;CONCLUSION:Tumor redox parameters measured by 62Cu-ATSM PET may be determinants of HNC patient outcomes and help define optimal patient-specific treatments.
  • Metabolic tumor burden predicts prognosis of ovarian cancer patients who receive platinum-based adjuvant chemotherapy.
    Yamamoto M, Tsujikawa T, Fujita Y, Chino Y, Kurokawa T, Kiyono Y, Okazawa H, Yoshida Y
    Cancer Sci 107(4) 478-485 Apr.  2016 Refereed
  • Impact on PET texture features of imaging biomarkers for predicting survival of patients with uterine sarcoma-preliminary results.
    M.Yamamoto, T.Tsujikawa, H.Okazawa, Y.Yoshida
    Biomarker J 2(1) e3017 Mar.  2016 Refereed
  • Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.
    T.Fujioka, K.Inohara, Y.Okamoto, Y.Masuya, M.Ishitobi, DN.Saito, M.Jung, S.Arai, Y.Matsumura, TX.Fujisawa, K.Narita, K.Suzuki, KJ.Tsuchiya, N.Mori, T.Katayama, M.Sato, T.Munesue, H.Okazawa, A.Tomoda, Y.Wada, H.Kosaka
    Mol Autism 7 19 Mar.  2016 Refereed
    BACKGROUND:Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, an all-in-one eye-tracking system for early detection of ASD in toddlers. Because abnormal gaze patterns have been documented in various ASD age groups, we predicted that Gazefinder might also detect gaze abnormality in adolescents and adults. In this study, we tested whether Gazefinder could identify unique gaze patterns in adolescents and adults with ASD.;METHODS:We measured the percentage of eye fixation time allocated to particular objects depicted in movies (i.e., eyes and mouth in human face movies, upright and inverted biological motion in movies that presented these stimuli simultaneously, and people and geometry in movies that presented these stimuli simultaneously) by male adolescents and adults with ASD (N = 26) and age-matched males with typical development (TD; N = 35). We compared these percentages between the two groups (ASD and TD) and with scores on the social responsiveness scale (SRS). Further, we conducted discriminant analyses to determine if fixation times allocated to particular objects could be used to discriminate between individuals with and without ASD.;RESULTS:Compared with the TD group, the ASD group showed significantly less fixation time at locations of salient social information (i.e., eyes in the movie of human faces without lip movement and people in the movie of people and geometry), while there were no significant groupwise differences in the responses to movies of human faces with lip movement or biological motion. In a within-group correlation analysis, a few of the fixation-time items correlated with SRS, although most of them did not. No items significantly correlated with SRS in both ASD and TD groups. The percentage fixation times to eyes and people, which exhibited large effect sizes for the group difference, could differentiate ASD and TD with a sensitivity of 81.0% and a specificity of 80.0%.;CONCLUSIONS:These findings suggest that Gazefinder is potentially a valuable and easy-to-use tool for objectively measuring unique gaze patterns and discriminating between ASD and TD in male adolescents and adults.
  • Different prognostic implications of 18F-FDG PET between histological subtypes in patients with cervical cancer.
    T.Rahman, T.Tsujikawa, M.Yamamoto, Y.Chino, A.Shinagawa, T.Kurokawa, T.Tsuchida, H.Kimura, Y.Yoshida, H.Okazawa
    Medicine (Baltimore) 95(9) e3017 Mar.  2016 Refereed
  • Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders.
    T.Morita, H.Kosaka, D.N.Saito, T.Fujii, M.Ishitobi, T.Munesue, K.Inohara, H.Okazawa, R.Kakigi, N.Sadato
    Res Autism Spectr Disord 26(0) 16-32 Mar.  2016 Refereed
  • Prognostic value of dual-time-point 18F-FDG PET for idiopathic pulmonary fibrosis.
    Y.Umeda, Y.Demura, M.Morikawa, M.Anzai, M.Kadowaki, S.Ameshima, T.Tsuchida, T.Tsujikawa, Y.Kiyono, H.Okazawa, T.Ishizaki, T.Ishizuka
    J Nucl Med 56(12) 1869-1875 Dec.  2015 Refereed
  • Sex differences in the default mode network with regard to autism spectrum traits: A resting state fMRI study.
    M.Jung, M.Mody, DN.Saito, A.Tomoda, H.Okazawa, Y.Wada, H.Kosaka
    PLOS One  10(11) e0143126 Nov.  2015 Refereed
  • Ethnic differences in COMT genetic effects on striatal grey matter alterations associated with childhood ADHD: A voxel-based morphometry study in a Japanese sample.
    K.Shimada, TX.Fujisawa, S.Takiguchi, H.Naruse, H.Kosaka, H.Okazawa, A.Tomoda
    World J Biol Psychiatry 1-7 Nov.  2015 Refereed
  • Intrathoracic benign goiter imaged by 18F-FDG-PET: A case report.
    S.Wakahara, T.Konoshita, A.Sakai, T.Nakaya, M.Ichikawa, K.Yamamoto, M.Imagawa, H.Kimura, H.Okazawa, T.Ishizuka
    Medicine (Baltimore) 94(32) e1387 Aug.  2015 Refereed
  • Reduced visual cortex grey matter volume in children and adolescents with reactive attachment disorder.
    K.Shimada, S.Takiguchi, S.Mizushima, TX.Fujisawa, DN.Saito, H.Kosaka, H.Okazawa, A.Tomoda
    NeuroImage: Clin 9 13-19 Jul.  2015 Refereed
  • Evaluation of staging and early response to chemotherapy with whole-body diffusion-weighted magnetic resonance imaging in malignant lymphoma patients: A comparison with FDG-PET/CT
    K Tsuji, S Kishi, T Tsuchida, T Yamauchi, S Ikegaya, Y Urasaki, Y Fujiwara, T Ueda, H Okazawa, H Kimura
    J Magn Reson Imaging 41(6) 1601-1607 Jun.  2015 Refereed
  • Evaluation of staging and early response to chemotherapy with whole-body diffusion-weighted MRI in malignant lymphoma patients: A comparison with FDG-PET/CT
    K.Tsuji, S.Kishi, T.Tsuchida, T.Yamauchi, S.Ikegaya, Y.Urasaki, Y.Fujiwara, T.Ueda, H.Okazawa, H.Kimura
    J Magn Reson Imaging 41(6) 1601-1607 Jun.  2015 Refereed
  • Predictive value of early stage uptake of 3'-deoxy-3'-18F-fluorothymidine in cancer cells treated with charged particle irradiation.
    C.Lin, K.Kume, T.Mori, ME.Martinez , H.Okazawa, Y.Kiyono
    J Nucl Med 56(6) 945-950 Jun.  2015 Refereed
  • Increased oxidative stress is related to disease severity in the ALS motor cortex: A PET study
    M.Ikawa,H.Okazawa,T.Tsujikawa,A.Matsunaga,O.Yamamura,T.Mori,T.Hamano,Y,Kiyono,Y.Nakamoto,M.Yoneda
    Neurology 84(20) 2033-2039 May  2015 Refereed
  • The co-occurrence of zinc deficiency and social isolation has the opposite effects on mood compared with either condition alone due to changes in the central norepinephrine system
    H.Mitsuya, N.Omata, Y.Kiyono, T.Mizuno, T.Murata, K.Mita, H.Okazawa, Y.Wada
    Behav Brain Res 284 125-130 May  2015 Refereed
  • Comparison of image quality with 62Cu and 64Cu-labeled radiotracers in positron emission tomography whole-body phantom imaging.
    M.Kobayashi, T.Mori, T.Tsujikawa, K.Ogai, J.Sugama, Y.Kiyono, K.Kawai, H.Okazawa
    Hell J Nucl Med 18(2) 103-107 May  2015 Refereed
  • The co-occurrence of zinc deficiency and social isolation has the opposite effects on mood compared with either condition alone due to changes in the central norepinephrine system
    Mitsuya H, Omata N, Kiyono Y, Murata T, Mita K, Okazawa H, Wada Y
    Behav Brain Res 1(284) 125-130 Feb.  2015 Refereed
  • Autistic empathy toward autistic others
    Komeda H, Kosaka H, Saito DN, Mano Y, Jung M, Fujii T, Yanaka HT, Munesue T, Ishitobi M, Sato M, Okazawa H
    Soc Cogn Affect Neurosci. 10(2) 145-152 Feb.  2015 Refereed
  • Autistic empathy toward autistic others
    H.Komeda, H.Kosaka, DN.Saito, Y.Mano, M.Jung, T.Fujii, HT.Yanaka, T.Munesue, M.Ishitobi, M.Sato, H.Okazawa
    Social Cognitive and Affective Neuroscience  10(2) 145-152 2015 Refereed
  • Brain imaging for oxidative stress and mitochondrial dysfunction in neurodegenerative disease
    H.Okazawa, M.Ikawa, T.Tsujikawa, Y.Kiyono, M.Yoneda
     58(4) 387-397 Dec.  2014 Refereed
  • Assessing tumor hypoxia in head and neck cancer by PET with 62Cu-diacetyl-bis(N4-methylthiosemicarbazone)
    Sato Y, Tsujikawa T, Oh M, Mori T, Kiyono Y, Fujieda S, Kimura H, Okazawa H
    Clin Nucl Med 39(12) 1027-1032 Dec.  2014 Refereed
  • Neuronal plasticity in depressive or manic states - New assessment of our hypothesis: Mania is an extension of depression from the perspective of neuronal plasticity
    Omata N, Mizuno T, Mitsuya H, Mita K, Higashi Y, Kamichika T, Kiyono Y, Okazawa H, Wada Y
     24(3) 845-846 Oct.  2014 Refereed
  • Attenuation of the contingency detection effect in the extrastriate body area in autism spectrum disorder
    Okamoto Y, Kitada R, Tanabe HC, Hayashi MJ , Kochiyama T, Munesue T, Ishitobi M, Saito DN, Yanaka HT, Omori M, Wada Y, Okazawa H, Sasaki AT, Morita T, Itakura S, Kosaka H, Sadato N
     87 66-76 Oct.  2014 Refereed
  • Evaluation of staging and early response to chemotherapy with whole-body diffusion-weighted magnetic resonance imaging in malignant lymphoma patients: A comparison with FDG-PET/CT
    Tsuji K, Kishi S, Tsuchida T, Yamauchi T, Ikegaya S, Urasaki Y, Fujiwara Y, Ueda T, Okazawa H, Kimura H
    Journal of Magnetic Resonance Imaging Aug.  2014 Refereed
  • Pathophysiological decrease in the regional cerebral blood flow in Hashimoto’s encephalopathy: a multiple-case SPECT study
    T.Muramatsu, M.Ikawa, M.Yoneda, K.Sugimoto, A.Matsunaga, O.Yamamura, T. Hamano, H.Okazawa, Y.Nakamoto
     72(42006) 13-19 Jul.  2014 Refereed
  • Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits
    M.Jung, H.Kosaka, D.N.Saito, Ishitobi Makoto, T.Morita, K.Inohara, M.Asano, S.Arai, T.Munesue, Tomoda ?A., Y.Wada, N.Sadato, H.Okazawa, T.Iidaka
     5 35 Jun.  2014 Refereed
  • Diagnosis of complex renal cystic masses and solid renal lesions using PET imaging: comparison of 11C-acetate and 18F-FDG PET imaging
    N.Oyama, H.Ito, N.Takahara, Y.Miwa, H.Akino, T.Kudo, H.Okazawa, Y.Fujibayashi, K.Komatsu, K.Tsukahara, O.Yokoyama
     39(3) 208-214 Mar.  2014 Refereed
  • Depressive mood modulates the anterior lateral CA1 and DG/CA3 during a pattern separation task in cognitively intact individuals: A functional MRI study
    Fujii T, Saito DN, Yanaka HT, Kosaka H, Okazawa H
     24(2) 212-224 Feb.  2014 Refereed
  • Diagnosis of Complex Renal Cystic Masses and Solid Renal Lesions Using PET Imaging Comparison of C-11-Acetate and F-18-FDG PET Imaging
    Oyama, Nobuyuki;Ito, Hideaki;Takahara, Noriko;Miwa, Yoshiji;Akino, Hironobu;Kudo, Takashi;Okazawa, Hidehiko;Fujibayashi, Yasuhisa;Komatsu, Kazuto;Tsukahara, Kenji;Yokoyama, Osamu
    CLINICAL NUCLEAR MEDICINE 39(3) E208-E214 2014
  • Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits
    Jung, Minyoung;Kosaka, Hirotaka;Saito, Daisuke N.;Ishitobi, Makoto;Morita, Tomoyo;Inohara, Keisuke;Asano, Mizuki;Arai, Sumiyoshi;Munesue, Toshio;Tomoda, Akemi;Wada, Yuji;Sadato, Norihiro;Okazawa, Hidehiko;Iidaka, Tetsuya
    MOLECULAR AUTISM 5 2014
  • Pathophysiological Decrease in the Regional Cerebral Blood Flow in Hashimoto's Encephalopathy: A Multiple-Case SPECT Study
    Muramatsu, Tomoko;Ikawa, Masamichi;Yoneda, Makoto;Sugimoto, Katsuya;Matsunaga, Akiko;Yamamura, Osamu;Hamano, Tadanori;Okazawa, Hidehiko;Nakamoto, Yasunari
    EUROPEAN NEUROLOGY 72(1-2) 13-19 2014
  • Assessing Tumor Hypoxia in Head and Neck Cancer by PET With Cu-62-Diacetyl-Bis(N-4-Methylthiosemicarbazone)
    Sato, Yoshitaka;Tsujikawa, Tetsuya;Oh, Myungmi;Mori, Tetsuya;Kiyono, Yasushi;Fujieda, Shigeharu;Kimura, Hirohiko;Okazawa, Hidehiko
    CLINICAL NUCLEAR MEDICINE 39(12) 1027-1032 2014
  • Neuronal plasticity in depressive or manic states - New assessment of our hypothesis: Mania is an extension of depression from the perspective of neuronal plasticity
    Omata, Naoto;Mizuno, Tomoyuki;Mitsuya, Hironori;Mita, Kayo;Higashi, Yoshie;Kamichika, Tetsuro;Kiyono, Yasushi;Okazawa, Hidehiko;Wada, Yuji
    MEDICAL HYPOTHESES 83(6) 845-846 2014
  • Attenuation of the contingency detection effect in the extrastriate body area in autism spectrum disorder
    Okamoto, Yuko;Kitada, Ryo;Tanabe, Hiroki C.;Hayashi, Masamichi J.;Kochiyama, Takanori;Munesue, Toshio;Ishitobi, Makoto;Saito, Daisuke N.;Yanaka, Hisakazu T.;Omori, Masao;Wada, Yuji;Okazawa, Hidehiko;Sasaki, Akihiro T.;Morita, Tomoyo;Itakura, Shoji;Kosaka, Hirotaka;Sadato, Norihiro
    NEUROSCIENCE RESEARCH 87 66-76 2014
  • Mania:Not the opposite of depression, but an extension?Neuronal plasticity and polarity
    T.Mizuno, N.Omata, T.Murata, H.Mitsuya, N.Maruoka, K.Mita, Y.Kiyono, H.Okazawa, H.Ikeda, Y.Wada
     81(2) 175-9 Aug.  2013 Refereed
  • Imaging the early response to chemotherapy in advanced lung cancer with diffusion-weighted magnetic resonance imaging compared to fluorine-18 fluorodeoxyglucose positron emission tomography and computed tomography
    T.Tsuchida, M. Morikawa, Y. Demura, Y. Umeda, H. Okazawa, H. Kimura
    Journal of Magnetic Resonance Imaging 38(1) 80-88 Jul.  2013 Refereed
  • 18F-FDG PET/CT for diagnosis of osteosclerotic and osteolytic vertebral metastatic lesions: Comparison with bone scintigraphy
    K.Uchida, H.Nakajima, T.Miyazaki, T.Tsuchida, T.Hirai, D.Sugita, S.Watanabe, N.Takeura, A.Yoshida, H.Okazawa, H.Baba
     7(2) 96-103 Jun.  2013 Refereed
  • 18F-fluorothymidine PET is a potential predictive imaging biomarker of the response to gemcitabine-based chemotherapeutic treatment for recurrent ovarian cancer: preliminary results in three patients
    H.Tsuyoshi, F.Morishita, M.Orisaka, H.Okazawa, Y.Yoshida
    Clin Nucl Med 38(7) 560-3 Jun.  2013 Refereed
  • Episodic memory retrieval for story characters in high-functioning autism
    H.Komeda, H.Kosaka, D.N.Saito, K.Inohara, T.Munesue, M.Ishitobi, M.Sato, H.Okazawa
    Mol Autism 4(1) 20 Jun.  2013 Refereed
  • Carbon-11-acetate positron emission tomography(PET), versus fluorine-18 fluorodeoxyglucose PET and CT for the diagnosis of recurrent prostate cancer after radical prostatectomy in cases of prostate specific antigen of more than 1 to 3ng/ml
    N.Oyama, H.Ito, Y.Aoki, Y.Miwa, H.Akino, T.Kudo, H.Okazawa, Y.Fujibayashi, M.Welch, O.Yokoyama
     16(2) 146-147 May  2013 Refereed
  • 18F-FES and 18F-FDG PET for Differential Diagnosis and Quantitative Evaluation of Mesenchymal Uterine Tumors: Correlation with Immunohistochemical Analysis
    Z.Zhao, Y.Yoshida, T.Kurokawa, Y.Kiyono, T.Mori, H.Okazawa
     54(4) 499-506 Apr.  2013 Refereed
  • Reverse blood flow-glucose metabolism mismatch indicates preserved oxygen metabolism in patients with revascularised myocardial infarction
    Y.Fukuoka, A.Nakano, H.Uzui, N.Amaya, K.Ishida, K.Arakawa, T.Kudo, H.Okazawa, T.Ueda, J-D.Lee, H.Tada
     40(8) 1155-1162 Apr.  2013 Refereed
  • Region-specific causal mechanism in the effects of ammonia on cerebral glucose metabolism in the rat brain
    Maruoka N, Murata T, Omata N, Mitsuya H, Kiyono Y, Okazawa H, Wada Y
     120(3) 375-382 Mar.  2013 Refereed
  • The 34rd report on survey of the adverse reaction to radiopharmaceuticals (the 37th survey in 2011)
    Matsuda H, Arano Y, Okazawa H, Mizumura S, Yokoyama K, Yoshimura M
    Kaku Igaku (Jpn J Nucl Med) 50(1) 13-25 Feb.  2013 Refereed
  • Transport mechanism of 11C-labeled L- and D-methionine in human-derived tumor cells
    M.Kobayashi, F.Hashimoto, K.Ohe, T.Nadamura, K.Nishi, N.Shikano, R.Nishii, T.Higashi, H.Okazawa, K.Kawai
     39(8) 1213-1218 Nov.  2012 Refereed
  • Effect of dietary zinc deficiency on ischemic vulnerability of the brain
    N.Omata, T.Murata, N.Maruoka, H.Ikeda, H.Mitsuya, T.Mizuno, K.Mita, M.Asano, Y.Kiyono, H.Okazawa, Y.Wada
    Neuroscience Letters 531(1) 42290 Nov.  2012 Refereed
  • Hard to tune in": Neural mechanisms of live face-to-face interaction in individuals with high-functioning autistic spectrum disorder"
    H.C.Tanabe, H.Kosaka, D.Saito, T.Koike, M.J.Hayashi, K.Izuma, H.Komeda, M.Ishitobi, M.Omori, T.Munesue, H.Okazawa, Y.Wada, N.Sadato
     6(268) 42019 Sep.  2012 Refereed
  • Relationship between microcirculatory dysfunction and resolution of ST-segment elevation in the early phase after primary angioplasty in patients with ST-segment elevation myocardial infarction
    N. Amaya, A.Nakano, H.Uzui, Y. Mitsuke, T. Geshi, H.Okazawa, T.Ueda, J-D.Lee
    Int J Cardiol 159(2) 144-149 Aug.  2012 Refereed
  • Is misery perfusion still a predictor of stroke in symptomatic major cerebral artery disease?
    H.Yamauchi, T.Higashi, S.Kagawa, R.Nishii, T.Kudo, K.Sugimoto, H.Okazawa, H.Fukuyama
     135(8) 2515-2526 Aug.  2012 Refereed
  • Positron Emission Tomography Radiopharmaceuticals for Sex Steroid Hormone Receptor Imaging
    Y.Kiyono, T.Mori, H.Okazawa
     19(20) 3266-3270 Jun.  2012 Not refereed
  • Oestrogen-related tumour phenotype: PET characterisation with 18F-FDG and 18F-FES
    T.Tsujikawa, Y.Yoshida, H.Maeda, T.Tsuchida, T.Mori, Y.Kiyono, H.Kimura, H.Okazawa
     85(1015) 1020-1024 Jun.  2012 Refereed
  • Different distribution of 62Cu ATSM and 18F-FDG in head-and-neck cancers
    A.Kositwattanarerk, M.Oh, T.Kudo, Y.Kiyono, T.Mori, Y.Kimura, R.Maruyama, Y.Fujibayashi, S.Fujieda, H.Okazawa
     37(3) 252-257 Mar.  2012 Refereed
  • Beneficial effects of statin treatment on coronary microvascular dysfunction and left ventricular remodeling in patients with acute myocardial infarction
    K.Ishida, T.Geshi, A.Nakano, H.Uzui, Yasuhiko MITSUKE, H.Okazawa, T.Ueda, J-D.Lee
    Int J Cardiol. Mar.  2012 Refereed
  • Emotional responses associated with self-face processing in individuals with autism spectrum disorders:An fMRI study
    T.Morita, H.Kosaka, DN.Saito, M.Ishitobi, T.Munesue, S.Itakura, M.Omori, H.Okazawa, Y.Wada, N.Sadato
     7(42067) 223-239 Mar.  2012 Refereed
  • Appropriate parameters of ordered-subset expectation maximization algorithm on measurement of myocardial blood flow and oxygen consumption with 11C-acetate PET
    M.Kobayashi, T.Mori, Y.Kiyono, T.Tsujikawa, R.Maruyama, Y.Higaki, N.Shikano, R.Nishii, K.Kawai, T.Kudo, H.Okazawa
     33(2) 130-138 Feb.  2012 Refereed
  • Radiolabeled Cu-ATSM as a novel indicator of over-reduced intracellular state due to mitochondrial dysfunction: studies with mitochondrial DNA-less rho0 cells and cybrids carrying MELAS DNA mutation
    Y.Yoshii, M.Yoneda, M.Ikawa, T.Furukawa, Y.Kiyono, T.Mori, H.Yoshii, N.Oyama, H.Okazawa, T.Saga, Y.Fujibayashi
     39(2) 117-185 Feb.  2012 Refereed
  • The 33rd report on survey of the adverse reaction to radiopharmaceuticals (the 36th survey in 2010)
    H.Matsuda, Y.Arano, H.Okazawa, T.Okamura, S.Mizumura, K.Yokoyama
    Kaku Igaku (Jpn J Nucl Med) 49(1) 42018 Feb.  2012 Refereed
  • Acute hyperglycemia causes microvascular damage, leading to poor functional recovery and remodeling in patients with reperfused ST-segment elevation myocardial infarction
    K.Sarazawa, A.Nakano, H.Uzui, Y. Mitsuke, T. Geshi, H.Okazawa, T.Ueda, J-D.Lee
     Feb.  2012 Refereed
  • Cerebral oxygen metabolism of rats using injectable 15O-oxygen with a steady-state method
    M.Kobayashi, T.Mori, Y.Kiyono, V.N.Tiwari, R.Maruyama, K.Kawai, H.Okazawa
     32(1) 33-40 Jan.  2012 Refereed
  • Clinical significance of MRI/18F-FDG PET fusion imaging of the spinal cord in patients with cervical compressive myelopathy
    K.Uchida, H.Nakajima, H.Okazawa, H.Kimura, T.Kudo, S.Watanabe, A.Yoshida, H.Baba
     39(10) 1528-1537 Jan.  2012 Refereed
  • Role of PET/CT in gynecological tumors based on the revised FIGO staging classification
    T.Tsujikawa, T.Tsuchida, Y.Yoshida, T.Kurokawa, Y.Kiyono, H.Okazawa, H.Kimura
     36(9) e114-118 Sep.  2011 Refereed
  • Nanoimprinted scaffolds provide a novel 3D culture model facilitating spontaneous tumor cell migration and well-regulated spheroid formation
    Y.Yoshii, A.Waki, K.Yoshida, A.Kakezuka, M.Kobayashi, H.Namiki, Y.Kuroda, Y.Kiyono, H.Yoshii, T.Furukawa, T.Asai, H.Okazawa, J.G.Gelovani, Y.Fujibayashi
     32(26) 6052-6058 Sep.  2011 Refereed
  • Differentiation of histological subtypes in lung cancer with 18F-FDG-PET 3-point imaging and kinetic analysis
    T. Tsuchida, Y. Demura, M. Sasaki, M. Morikawa, Y. Umeda, T. Tsujikawa, T. Kudoh, H. Okazawa, H. Kimura
    Hell J Nucl Med 14(3) 224-7 Sep.  2011 Refereed
  • Assessment of therapeutic effect of sunitinib by 11C-acetate PET compared with FDG PET imaging in a patient with metastatic renal cell carcinoma
    N.Oyama, N.Takahara, Y.Hasegawa, K.Tanase, Y.Miwa, H.Akino, H.Okazawa, T.Kudo, Y.Fujibayashi, O.Yokoyama
     45(3) 217-219 Sep.  2011 Refereed
  • Kikuchi-Fujimoto disease; PET/CT assessment of a rare cause of cervical lymphadenopathy
    T.Tsujikawa, T.Tsuchida, Y.Imamura, M.Kobayashi, S.Asahi, K.Shimizu, K.Tsuji, Y.Kiyono, H.Okazawa, H.Kimura
     36(8) 661-664 Aug.  2011 Refereed
  • New radiosynthesis of 2-deoxy-2-[18F]fluoroacetamido-D-glucopyranose and its evaluation as a bacterial infections imaging agent
    M.E.Martinez, Y.Kiyono, S.Noriki, K.Inai, K.S.Mandap, M.Kobayashi, T.Mori, Y.Tokunaga, V.N.Tiwari, H.Okazawa, Y.Fujibayashi, T.Ido
     38(6) 807-817 Aug.  2011 Refereed
  • Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive compulsive disorder
    Berney A, Leyton M, Gravel P, Sibon I, Sookman D, Rosa-Nato P, Diksic M, Nakai A, Pinard G, Todorov C, H.Okazawa, Blier P, Nordahl TE, Benkelfat C
     68(7) 732-741 Jul.  2011 Refereed
  • Feasibility of 62Cu-ATSM PET for evaluation of brain ischaemia and misery perfusion in patients with cerebrovascular disease
    M.Isozaki, Y.Kiyono, Y.Arai, T.Kudo, T.Mori, R.Maruyama, K.Kikuta, H.Okazawa
     38(6) 1075-1082 Jun.  2011 Refereed
  • Prognostic value of dual-time-point (18)F-fluorodeoxyglucose positron emission tomography in patients with pulmonary sarcoidosis
    Y.Umeda, Y.Demura, M.Morikawa, S.Ameshima, T.Tsuchida, Y.Fujibayashi, H.Okazawa, T.Ishizaki
     16(4) 713-720 May  2011 Refereed
  • Increased glucose metabolism by FDG-PET correlates with reduced tumor angiogenesis in oral squamous cell carcinoma
    M.Nakamura, Y.Kitagawa, Y.Yamaaki, H.Hata, M.Kotsuji, Y.Fujibayashi, H.Okazawa, Y.Yonekura, K.Sano
    Odontology 100(1) 87-94 May  2011 Refereed
  • In vivo functional brain imaging and a therapeutic trial of l-arginine in MELAS patients
    M.Yoneda, M.Ikawa, K.Arakawa, T.Kudo, H.Kimura, Y.Fujibayashi, H.Okazawa
     May  2011 Refereed
  • Differential amygdala response to lower face in patients with autistic spectrum disorders: An fMRI study
    M.Ishitobi, H.Kosaka, M.Omori, Y.Matsumura, T.Munesue, K.Mizukami, T.Shimoyama, T.Murata, N.Sadato, H.Okazawa, Y.Wada
     5(2) 910-919 Apr.  2011 Refereed
  • Internal radiotherapy with copper-64-diacetyl-bis (N4-methylthiosemicarbazone) reduces CD133+ highly tumorigenic cells and metastatic ability of mouse colon carcinoma
    Y.Yoshii, T.Furukawa, Y.Kiyono, R.Watanabe, T.Mori, H.Yoshii, T.Asai, H.Okazawa, M.J.Welch, Y.Fujibayashi
    Nuclear Medicine and Biology 38(2) 151-157 Feb.  2011 Refereed
  • Development of an H215O steady-state method combining a bolus and slow increasing injection with a multi-programming syringe pump
    M.Kobayashi, Y.Kiyono, R.Maruyama, T.Mori, K.Kawai, H.Okazawa
     31(2) 527-534 Feb.  2011 Refereed
  • Functional oestrogen receptor alpha imaging in endometrial carcinoma using 16α-[18F]fluoro-17β-oestradiol PET
    T.Tsujikawa, Y.Yoshida, Y.Kiyono, T.Kurokawa, T.Kudo, Y.Fujibayashi, F.Kotsuji, H.Okazawa
     38(1) 37-45 Jan.  2011 Refereed
  • Additional value of 16α-[18F]fluoro-17β-estradiol PET for differential diagnosis between uterine sarcoma and leiomyoma in patients with positive or equivocal findings on [18F]fluorodeoxyglucose PET
    Y.Yoshida, Y.Kiyono, T.Tsujikawa, T.Kurokawa, H.Okazawa, F.Kotsuji
     38(10) 1824-1831 Jan.  2011 Refereed
  • Evaluation of striatal oxidative stress in patients with Parkinson's disease using [(62)Cu]ATSM PET
    M.Ikawa, H.Okazawa, T. Kudo, M.Kuriyama, Y.Fujibayashi, M.Yoneda
     38(945) 951 Jan.  2011 Refereed
  • Stay tuned": Inter-individual neural synchronization during mutual gaze and joint attention"
    D.N.Saito, H.C.Tanabe, K.Izuma, M.J.Hayashi, Y.Morito, H.Komeda, H.Uchiyama, H.Kosaka, H.Okazawa, Y.Fujibayashi, N.Sadato
     4(127) 42016 Nov.  2010 Refereed
  • Tumor hypoxic imaging and its clinical application
    H.Okazawa, 清野 泰
    Bio Clinica 25(9) 790-793 Aug.  2010 Not refereed
  • Clinical implication and prognosis of normal baseline cerebral blood flow with impaired vascular reserve in patients with major cerebral artery occlusive disease
    M.Isozaki, Y.Arai, T.Kudo, Y.Kiyono, M.Kobayashi, T.Kubota, K.Kikuta, H.Okazawa
     24(5) 371-377 Jun.  2010 Refereed
  • Copper-64-diacetyl-bis (N4-methylthiosemicarbazone) accumulates in rich regions of CD133+ highly tumorigenic cells in mouse colon carcinoma
    Y.Yoshii, T.Furukawa, Y.Kiyono, R.Watanabe, A.Waki, T.Mori, H.Yoshii, M.Oh, T.Asai, H.Okazawa, M.J.Welch, Y.Fujibayashi
    Nucl Med Biol 37(4) 395-404 May  2010 Refereed
  • Smaller Insula and Inferior Frontal Volumes in Young Adults with Pervasive Developmental Disorders
    H.Kosaka, M.Omori, T.Munesue, M.Ishitobi, Y. Matsumura, T.Takahashi, K.Narita, T.Murata, DN.Saito, H.Uchiyama, T.Morita, M.Kikuchi, K.Mizukami, H.Okazawa, N.Sadato, Y.Wada
     50(4) 1357-1363 May  2010 Refereed
  • Nuclear neuroimaging of pathophysiology
    Clin J Radiol 55(4) 483-486 Apr.  2010 Refereed
  • Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images
    T. Tsujikawa, M. Yoneda, Y. Shimizu, H. Uematsu, M. Toyooka, M. Ikawa, T. Kudo, H. Okazawa, M. Kuriyama, H. Kimura
     32(2) 143-149 Feb.  2010 Refereed
  • Comparison of the transcellular transport of FDG and D-glucose by the kidney epithelial cell line, LLC-PK1
    M.Kobayashi, N.Shikano, R.Nishii, Y.Kiyono, H.Araki, K.Nishi, M.Oh, H.Okudaira, M.Ogura, M.Yoshimoto, H.Okazawa, Y.Fujibayashi, K.Kawai
     31(2) 141-146 Feb.  2010 Refereed
  • Automatic labeling method for injectable 15O-oxygen using hemoglobin-containing liposome vesicles and its application for measurement of brain oxygen consumption by PET
    V.N.Tiwari, Y.Kiyono, M.Kobayashi, T.Mori, T.Kudo, H.Okazawa, Y.Fujibayashi
     37(1) 77-83 Jan.  2010 Refereed
  • Abnormal myocardial energy-production state in mitochondrial cardiomyopathy and acute response to L-arginine infusion
    K.Arakawa, T.Kudo, M.Ikawa, N.Morikawa, Y.Kawai, K.Sahashi, J-D.Lee, M.Kuriyama, I.Miyamori, H.Okazawa, M.Yoneda
     74(12) 2702-2711 Jan.  2010 Refereed
  • Pathophysiologic correlation between 62Cu-ATSM and 18F-FDG in lung cancer
    T.G.Lohith, T.Kudo, Y.Demura, Y.Umeda, Y.Kiyono, Y.Fujibayashi, H.Okazawa
     50(12) 1948-1953 Dec.  2009 Refereed
  • Effects of alendronate on bone metabolism in glucocorticoid-induced osteoporosis measured by 18F-fluoride PET: A prospective study
    K.Uchida, H.Nakajima, T.Miyazaki, T.Yayama, H.Kawahara, S.Kobayashi, T.Tsuchida, H.Okazawa, Y.Fujibayashi, H.Baba
     50(11) 1808-1814 Nov.  2009 Refereed
  • Validation of calculating the clearance rate constant (kmono) of [11C]acetate using parametric kmono image for myocardial oxidative metabolism
    R.Hussain, T.Kudo, T.Tsujikawa, M.Kobayashi, Y.Fujibayashi, H.Okazawa
     36(8) 877-882 Nov.  2009 Refereed
  • Assessment of fluorodeoxyglucose uptake by leiomyomas in relation to histopathologic subtype and the menstrual state
    Y.Yoshida, T.Tsujikawa, T.Kurokawa, T.Tsuji, Y.Imamura, Y.Fujibayashi, H.Okazawa, F.Kotsuji
    J Comput Assist Tomogr 33(6) 877-881 Nov.  2009 Refereed
  • Neurological improvement associated with resolution of irradiation-induced myelopathy: Serial magnetic resonance imaging and positron emission tomography findings
    K.Uchida, H.Nakajima, T.Takamura, S.Kobayashi, T.Tsuchida, H.Okazawa, H.Baba
     19(3) 274-276 Jul.  2009 Refereed
  • Dual-time-point 18F-FDG PET imaging for diagnosis of disease type and disease activity in patients with idiopathic interstitial pneumonia
    Y.Umeda, Y.Demura, T.Ishizaki, S.Ameshima, I.Miyamori, Y.Saito, T.Tsuchida, Y.Fujibayashi, H.Okazawa
     36(7) 1121-1130 Jul.  2009 Refereed
  • Relationship between plasma leptin level and brain structure in elderly:a voxel-based morphometric study
    K.Narita, H.Kosaka, H.Okazawa, T.Murata, Y.Wada
     65(11) 992-994 Jun.  2009 Refereed
  • Positron emission tomography in ovarian cancer: 18F-deoxy-glucose and 16alpha-18F-fluoro-17beta-estradiol PET
    Y.Yoshida, T.Kurokawa, T.Tsujikawa, H.Okazawa, F.Kotsuji
    Journal of Ovarian Research 2(1) 7 Jun.  2009 Refereed
  • Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism
    Y.Yoshii, T.Furukawa, H.Yoshii, T.Mori, Y.Kiyono, A.Waki, M.Kobayashi, T.Tsujikawa, T.Kudo, H.Okazawa, Y.Fujibayashi
     100(5) 821-827 May  2009 Refereed
  • Development of microwave-based automated nucleophilic [18F]fluorination system and its application to the production of [18F]flumazenil
    K.S.Mandap, T.Ido, Y.Kiyono, M.Kobayashi, T.G.Lohith, T.Mori, S.Kasamatsu, T.Kudo, H.Okazawa, Y.Fujibayashi
     36(4) 403-409 May  2009 Refereed
  • Clinical impact of hemodynamic parameter measurement for cerebrovascular disease using positron emission tomography and 15O-labeled tracers
    H.Okazawa, T.Kudo
     23(3) 217-227 May  2009 Refereed
  • High-resolution magnetic resonance imaging and 18FDG-PET findings of the cervical spinal cord before and after decompressive surgery in patients with compressive myelopathy
    K.Uchida, H.Nakajima, T.Yayama, S.Kobayashi, S.Shimada, T.Tsuchida, H.Okazawa, E. Mwaka, H.Baba
     34(11) 1185-1191 May  2009 Refereed
  • Usefulness of 18F-fluorodeoxyglucose positron emission tomography for diagnosing disease activity and monitoring therapeutic responses in patients with pulmonary mycobacteriosis
    Y.Demura, T.Tsuchida, Y.Umeda, D.Uesaka, M.Morikawa, S.Ameshima, T.Ishizaki, Y.Fujibayashi, H.Okazawa
    Eur J Nucl Med Mol Img 36(4) 632-639 Apr.  2009 Refereed
  • PET imaging of redox and energy states in stroke-like episodes of MELAS
    S.Ikawa, H.Okazawa, K.Arakawa, T.Kudo, H.Kimura, Y.Fujibayashi, M.Kuriyama, M.Yoneda
     9(2) 144-148 Apr.  2009 Refereed
  • 11C-Acetate PET imaging for renal cell carcinoma
    N.Oyama, H.Okazawa, N.Kusukawa, T.Kaneda, Y.Miwa, H.Akino, Y.Fujibayashi, Y.Yonekura, Welch, MJ, O.Yokoyama
     36(3) 422-427 Mar.  2009 Refereed
  • Preparation and evaluation of ethyl [18F]fluoroacetate as a pro-radiotracer of [18F]luoroacetate for the measurement of glial metabolism by PET
    T.Mori, Li-Quan Sun, M.Kobayashi, Y.Kiyono, H.Okazawa, T.Furukawa, H.Kawashima, M.J. Welch, Y.Fujibayashi
     36(2) 155-162 Feb.  2009 Refereed
  • Measurement of glucose metabolism in rat spinal cord slices with dynamic positron autoradiography
    X.Fan, T.Asai, K.Morioka, K.Uchida, H.Baba, K.Tanaka, J.Zhuang, H.Okazawa, Y.Fujibayashi
    Nucl Med Biol 36(2) 183-189 Feb.  2009 Refereed
  • The Effectiveness of 18F-FDG PET/CT combined with STIR MRI for diagnosing nodal involvement in the thorax
    M.Morikawa, Y.Demura, T.Ishizaki, S.Ameshima, I.Miyamori, M.Sasaki, T.Tsuchida, H.Kimura, Y.Fujibayashi, H.Okazawa
    J Nucl Med 50(1) 81-87 Jan.  2009 Refereed
  • Functional images reflect aggressiveness of endometrial carcinoma: Estrogen receptor expression combined with FDG-PET
    T.Tsujikawa, Y.Yoshida, T.Kudo, Y.Kiyono, T.Kurokawa, M.Kobayashi, T.Tsuchida, Y.Fujibayashi, F.Kotsuji, H.Okazawa
    J Nucl Med 50(10) 1598-1604 Jan.  2009 Refereed
  • Tumor uptake of radiolabeled acetate reflects the expression of cytosolic acetyl-CoA synthetase: implications for the mechanism of acetate PET
    Y.Yoshii, A.Waki, T.Furukawa, Y.Kiyono, T.Mori, H.Yoshii, T.Kudo, H.Okazawa, MJ Welch, Y.Fujibayashi
    Nuclear Medicine and Biology 36(7) 771-777 Jan.  2009 Refereed
  • Vasodilatory effect of adenosine triphosphate does not change cerebral blood flow - A PET study with 15O-water
    R.Hussain, T.Tsuchida, T.Kudo, M.Kobayashi, T.Tsujikawa, Y.Kiyono, Y.Fujibayashi, H.Okazawa
     23(8) 717-723 Jan.  2009 Refereed
  • A patient with partial seizures manifested as panic attacks and auditory hallucination
    H.Kosaka, T.Murata, T.Takahashi, M.Omori, H.Okazawa, Y.Wada
     2(1) 28-33 Jan.  2009 Refereed
  • Simple quantification of myocardial perfusion by pixel-by-pixel graphical analysis using carbon-11 acetate: comparison of the K-complexes of carbon-11 acetate and nitrogen-13 ammonia
    T.Kudo, T.Hata, S.Kagawa, Y.Kishibe, J.Iwasaki, A.Nakano, H.Okazawa
    Nucl Med Commun 29(8) 679-685 Aug.  2008 Refereed
  • Uterine tumors: Pathophysiologic imaging with 16α-[18F]fluoro-17β-estradiol and FDG-PET ? Initial experience
    T.Tsujikawa, Y.Yoshida, T.Mori, T.Kurokawa, Y.Fujibayashi, F.Kotsuji, H.Okazawa
    Radiology 248(2) 599-605 Aug.  2008 Refereed
  • Relationship between impaired microvascular function in the non-infarct-related area and early left ventricular remodeling in patients with myocardial infarction
    T.Geshi, A.Nakano, H.Uzui, H.Okazawa, Y.Yonekura, T.Ueda, J-D.Lee
    Int J Cardiol 126(6) 366-373 Jun.  2008 Refereed
  • 18F-FDG PET of common enhancing malignant brain tumors
    N.Kosaka, T.Tsuchida, H. Uematsu, H.Kimura, H.Okazawa, H.Itoh
    Am J Roentgenol 190(6) W365-W369 Jun.  2008 Refereed
  • Reproducibility of Semi-quantitative Parameters in FDG-PET Using Two Different PET Scanners: Influence of Attenuation Correction Method and Examination Interval
    T.Kamibayashi, T.Tsuchida, Y.Demura, T.Tsujikawa, H.Okazawa, T.Kudo, H.Kimura
    Mol Imaging Biol. 10(3) 162-166 May  2008 Refereed
  • Comparison of 18F-FDG PET and MRI in assessment of uterine smooth muscle tumors
    Y.Yoshida, T.Kurokawa, Y.Sawamura, A.Shinagawa, T.Tsujikawa, H.Okazawa, T.Tsuchida, Y.Imamura, N.Suganuma, F.Kotsuji
    J Nucl Med 49(5) 708-712 May  2008 Refereed
  • FDG positron emission tomography imaging of drug-induced pneumonitis
    M.Morikawa, Y.Demura, S.Mizuno, S.Ameshima, T.Ishizaki, H.Okazawa
     22(4) 335-338 May  2008 Refereed
  • Shorter examination method for the diagnosis of misery perfusion using count-based OEF elevation in 15O-Gas PET
    M.Kobayashi, T.Kudo, T.Tsujikawa, M.Isozaki, Y.Arai, Y.Fujibayashi, H.Okazawa
    J Nucl Med 49(2) 242-246 Feb.  2008 Refereed
  • Grading of brain glioma with 1-11C-acetate PET: comparison with 18F-FDG PET
    T.Tsuchida, H.Takeuchi, H.Okazawa, T.Tsujikawa, Y.Fujibayashi
    Nucl Med Biol 35(2) 171-176 Feb.  2008 Refereed
  • Distinctive FDG and FES accumulation pattern of two tamoxifen treated patients with endometrial hyperplasia
    T.Tsujikawa, H.Okazawa, Y.Yoshida, T.Mori, M.Kobayashi, T.Tsuchida, Y.Fujibayashi
    Ann Nucl Med 22(1) 73-77 Jan.  2008 Refereed
  • Does partial volume corrected maximum SUV based on count recovery coefficient in 3D-PET/CT correlate with clinical aggressiveness of non-Hodgkin lymphoma?
    T.Tsujikawa, H.Otsuka, N.Morita, H.Saegusa, M.Kobayashi, H.Okazawa, H.Nishitani
    Ann Nucl Med 22(1) 23-30 Jan.  2008 Refereed
  • Evaluation of dual-time point 18F-FDG PET imaging for staging in patients with lung cancer
    D.Uesaka, Y.Demura, T.Ishizaki, S.Ameshima, I.Miyamori, M.Sasaki, Y.Fujibayashi, H.Okazawa
     49(10) 1606-1612 Jan.  2008 Refereed
  • A 18F-FDG-positive, 67Ga-negative, and transferrin receptor expression-negative patient with diffuse large B-cell lymphoma
    T.Tsujikawa, H.Okazawa, T.Tsuchida, Y.Demura, Y.Imamura, Y.Fujibayashi
    Ann Nucl Med 21(6) 375-378 Aug.  2007 Refereed
  • The positron emission tomography with F18 17beta-estradiol has the potential to benefit diagnosis and treatment of endometrial cancer
    Y.Yoshida, T.Kurokawa, Y, Sawamura, A.Shinagawa, H.Okazawa, Y.Fujibayashi, F. Kotsuji
    Gynecol Oncol 104(3) 764-766 Mar.  2007 Refereed
  • In vivo imaging of estrogen receptor concentration in the endometrium and myometrium using FES PET - influence of menstrual cycle and endogenous estrogen level
    T.Tsuchida, H.Okazawa, T.Mori, M. Kobayashi, Y.Yoshida, Y.Fujibayashi, H.Itoh
    Nucl Med Biol 34(2) 205-210 Feb.  2007 Refereed
  • Can the detection of misery perfusion in chronic cerebrovascular disease be based on reductions in baseline CBF and vasoreactivity?
    H.Okazawa, T.Tsuchida, M. Kobayashi, Y.Arai, M. Pagani, M.Isozaki, Y. Yonekura
    Eur J Nucl Med Mol Imaging 34(1) 121-129 Jan.  2007 Refereed
  • Can the detection of misery perfusion in chronic cerebrovascular disease be based on reductions in baseline CBF and vasoreactivity?
    H.Okazawa, T.Tsuchida, M.Kobayashi, Y.Arai, M.Pagani, M.Isozaki, Y.Yonekura
    Eur J Nucl Med Mol Imaging 34(1) 121-129 Jan.  2007 Refereed
  • Comparative assessment of 18F-fluorodeoxyglucose PET and 99mTc-tetrofosmin SPECT for the prediction of functional recovery in patients with reperfused acute myocardial infarction
    H.Shirasaki, A.Nakano, H.Uzui, Y.Yonekura, H.Okazawa, T.Ueda, J-D.Lee
    Eur J Nucl Med Mol Imaging 33(7) 879-886 Jul.  2006 Refereed
  • Effects of 5-HT1B/1D receptor agonist rizatriptan on cerebral blood flow and blood volume in normal circulation
    H.Okazawa, T.Tsuchida, M.Pagani, T.Mori, M.Kobayashi, F.Tanaka, Y.Yonekura
    J Cereb Blood Flow Metab 26(1) 92-98 Jan.  2006 Refereed
  • Diagnosis of misery perfusion using noninvasive O-15 gas PET
    M.Kobayashi, H.Okazawa, T.Tsuchida, K.Kawai, Y.Fujibayashi, Y.Yonekura
    J Nucl Med 47(10) 1581-1586 Jan.  2006 Refereed
  • Focal glucose hypermetabolism in interictal state of West syndrome
    T. Kumada, H.Okazawa, H. Yamauchi, T. Kitoh, M. Ito
    Pediatr Neurol 34 47-50 Jan.  2006 Refereed
  • Altered patterns of blood flow response during visual stimulation in carotid artery occlusive disease
    +Yamauchi, H., +Kudoh, T., *Sugimoto, K., +Takahashi, M., +Kishibe, Y., Okazawa, H.
    NeuroImage 25(2) 554-560 Apr.  2005 Refereed
  • Pattern of collaterals, type of infarcts, and haemodynamic impairment in carotid artery occlusion
    Yamauchi, H., Kudoh, T., Sugimoto, K., Takahashi, M., Kishibe, Y., Okazawa, H.
    J Neurol Neurosurg Psychiatry 75(12) 1697-1701 Dec.  2004 Refereed
  • A simplified autoradiographic method with α-[14C]methyl-tryptophan to measure serotonin synthesis rate in the rat brain
    Okazawa, H., Nishizawa, S., Tsuchida, T., Yonekura, Y., Diksic, M.
    Nucl Med Biol 31(8) 1013-1019 Nov.  2004 Refereed
  • A simplified autoradiographic method with α-methyl-tryptophan to measure serotonin
    Nishizawa, S., Okazawa, H., Tsuchida, T., Diksic, M., Yonekura, Y.
     128-132 Sep.  2004 Not refereed
  • Measurement of arterial part of vascular volume (V0) for the evaluation of hemodynamic changes in cerebrovascular disease
    Okazawa, H., Yamauchi, H., Yonekura, Y.
    Quantitation in Biomedical Imaging with PET and MRI ICS 1265 218-227 Aug.  2004 Refereed
  • Evaluation of positron emission tomography with tracer 18-fluorodeoxyglucose in addition to magnetic resonance imaging in the diagnosis of ovarian cancer in selected women after ultrasonography
    Kawahara, K., Yoshida, Y., Kurokawa, T., Suzuki, Y., Nagahara, K., Tsuchida, T., Okazawa, H., Fujibayashi, Y., Yonekura, Y., Kotsuji, F.
     28(4) 505-516 Jul.  2004 Refereed
  • Effects of metabolite correction for arterial input function on quantitative receptor images with 11C-flumazenil in clinical positron emission tomography studies
    Okazawa, H., Yamauchi, H., Sugimoto, K., Magata, Y., Kudo, T., Yonekura, Y.
    J Comput Assist Tomogr 28(3) 428-435 May  2004 Refereed
  • Expression of GLUT-1 Glucose Transfer, Cellular Proliferation Activity, and Grade of Tumor Correlate with?[F-18]- Fluorodeoxyglucose uptake by Positron Emission Tomography in Epithelial Tumors of the Ovary
    Kurokawa, T, Yoshida, T, Kawahara, K, Tsutida, T, Okazawa, H, Fujibayashi, Y, Yonekura, Y, Kotsuji, F
     109(6) 926-932 May  2004 Refereed
  • Database of normal human cerebral blood flow, cerebral blood volume, cerebral oxygen extraction fraction and cerebral metabolic rate of oxygen measured by positron emission tomography with 15O-labelled carbon dioxide or water, carbon monoxide and oxygen: a multicentre study in Japan
    Ito, H., Kanno, I., Kato, C., Sasaki, T., Ishii, K., Ouchi, Y., Iida, A., Okazawa, H., Hayashida, K., Tsuyuguchi, N., Ishii, K., Kuwabara, Y., Senda, M.
    Eur J Nucl Med Mol Imaging 31(5) 635-643 May  2004 Refereed
  • Incremental benefits of FDG positron emission tomography over CT alone for the preoperative staging of ovarian cancer
    Yoshida, Y., Kurokawa, T., Kawahara, K., Tsuchida, T., Okazawa, H., Fujibayasi, Y., Yonekura, Y., Kotsuji, F.
    Am J Roentgenol 182(1) 227-233 Jan.  2004 Refereed
  • Oxygen extraction fraction and acetazolamide reactivity in symptomatic carotid artery disease
    Yamauchi, H., Okazawa, H., Kishibe, Y., Sugimoto, K., Takahashi, M.
    J Neurol Neurosurg Psychiatry 75(1) 33-37 Jan.  2004 Refereed
  • The effect of deafferentation on cerebral blood flow response to acetazolamide
    Yamauchi, H., Okazawa, H., Sugimoto, K., Kishibe, Y., Takahashi, M.
    AJNR Am J Neuroradiol 25(1) 92-96 Jan.  2004 Refereed
  • Measurement of brain regional α-[11C] methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression
    Rosa-Neto, P., Diksic, M., Okazawa, H., Leyton, M., Ghadirian, N., Mzengeza, S., Nakai, A., Debonnel, G., Blier, P., Benkelfat, C.
     61(6) 556-563 2004 Refereed
  • Relationship between vasodilatation and cerebral blood flow increase in impaired hemodynamics -a PET study with the acetazolamide test in cerebrovascular disease
    H.Okazawa, H.Yamauchi, H.Toyoda, K.Sugimoto, Y.Fujibayashi, Y.Yonekura
    J Nucl Med 44(12) 1875-1883 Dec.  2003 Refereed
  • The effect of acetazolamide on the changes of cerebral blood flow and oxygen metabolism during visual stimulation
    Yamauchi, H., Okazawa, H., Kishibe, Y., Sugimoto, K., Takahashi, M.
    Neuroimage 20(1) 543-549 Sep.  2003 Refereed
  • Differences in vasodilatory capacity and changes in cerebral blood flow induced by acetazolamide in patients with cerebrovascular disease
    Okazawa, H., Yamauchi, H., Sugimoto, K., Takahashi, M.
    J Nucl Med 44(9) 1371-1378 Sep.  2003 Refereed
  • α-[11C]-Methyl-L-tryptophan PET identifies the epileptogenic tuber and correlates with interictal spike frequency
    Fedi, M., Reutens, D.C., Andermann, F., Okazawa, H., Boling, W., White, C., Dubeau, F., Nakai, A., Gross, D.W., Andermann, E., Diksic, M.
    Epilepsy Research 52(3) 203-213 2003 Refereed
  • Quantitative evaluation of myocardial blood flow and ejection fraction with a single dose of 13NH3 and gated PET
    H.Okazawa, M. Takahashi, T. Hata, K. Sugimoto, Y. Kishibe, T. Tsuji
    J Nucl Med 43(8) 999-1005 Aug.  2002 Refereed
  • Changes in blood flow and oxygen metabolism during visual stimulation in cerebrovascular disease: Effect of baseline perfusion and oxygen metabolism
    H.Yamauchi, H.Okazawa, Y.Kishibe, K.Sugimoto, M.Takahashi
    Stroke 33(5) 1294-1300 May  2002 Refereed
  • Reduced blood flow response to acetazolamide reflects pre-existing vasodilatation and decreased oxygen metabolism in major cerebral arterial occlusive disease
    H. Yamauchi, H.Okazawa, Y. Kishibe, K. Sugimoto, M. Takahashi
    Eur J Nucl Med 29(10) 1349-1356 Jan.  2002 Refereed
  • Autosomal dominant epilepsy with febrile seizures plus with missense mutations of the (Na+)-channel α1 subunit gene, SCN1A
    M.Ito, H. Nagafuji, H.Okazawa, K.Yamakawa, T.Sugawara, E.Mazaki-Miyazaki, S.Hirose, G.Fukuma, A.Mitsudome, K.Wada, S.Kaneko
    Epilepsy Res 48(1) 15-23 Jan.  2002 Refereed
  • Effects of acetazolamide on cerebral blood flow, blood volume and oxygen metabolism: A PET study with healthy volunteers
    H.Okazawa, H.Yamauchi, K.Sugimoto, H.Toyoda, Y.Kishibe, M.Takahashi
    J Cereb Blood Flow Metab 21(12) 1472-1479 Dec.  2001 Refereed
    DOI:1
  • Reduction in serotonin synthesis following acute and chronic treatments with paroxetine, a selective serotonin reuptake inhibitor in the rat brain: An autoradiographic study with alpha-[14C]methyl-L-tryptophan
    Y.Yamane, H.Okazawa, P.Blier, M.Diksic
    Biochem Pharmacol 62(11) 1481-1489 Dec.  2001 Refereed
  • Quantitative comparison of the bolus and steady-state methods for measurement of cerebral perfusion and oxygen metabolism: PET study using 15O-gas and water
    H.Okazawa, H.Yamauchi, K.Sugimoto, M.Takahashi, H.Toyoda, Y.Kishibe, H.Shio
    J Cereb Blood Flow Metab 21(7) 793-803 Jul.  2001 Refereed
    DOI:1
  • Effect of vascular radioactivity on regional values of cerebral blood flow: evaluation of methods for H215O PET to distinguish cerebral perfusion from blood volume
    H.Okazawa, M.Vafaee
    J Nucl Med 42(7) 1032-1039 Jul.  2001 Refereed
    DOI:1
  • Brain regional alpha-[11C]methyl-L-tryptophan trapping in impressive subjects with borderline personality disorder
    M.Leyton, H.Okazawa, M.Diksic, J.Paris, P.Rosa, S.Mzengeza, S.N.Young, P.Blier, C.Benkelfat
    Am J Psychiatry 158(5) 775-782 May  2001 Refereed
    DOI:1
  • Localizing value of α-Methyl-L-Tryptophan PET in Intractable Epilepsy of Neocortical Origin
    Fedi M, Reutens D, Okazawa H, Andermann F, Boling W, Dubeau F, White C, Nakai A, Gross DW, Andermann E, Diksic M
    Neurology 57(11) 1629-1636 Jan.  2001 Refereed
  • Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and a-[11C]methyl-L-tryptophan
    H.Okazawa, M.Leyton, C.Benkelfat, S.Mzengeza, M.Diksic
    J Psychiatry Neurosci 25(4) 359-370 Sep.  2000 Refereed
    DOI:1
  • Long-term changes of hemodynamics and metabolism after carotid artery occlusion
    H.Yamauchi, H.Fukuyama, Y.Nagahama, C.Oyanagi, H.Okazawa, M.Ueno, J.Konishi, H.Shio
     54(11) 2095-2102 Jun.  2000 Refereed
    DOI:1
  • A decrease in regional cerebral blood volume and hematocrit in crossed cerebellar diaschisis
    H.Yamauchi, H.Fukuyama, Y.Nagahama, H.Okazawa, J.Konishi
    Stroke 30(7) 1429-1431 Jul.  1999 Refereed
    DOI:1
  • Effects of acute and chronic administration of the serotonin1A agonist buspirone on serotonin synthesis in the rat brain
    H.Okazawa, F.Yamane, P.Blier, M.Diksic
    J Neurochem 72(5) 2022-2031 May  1999 Refereed
    DOI:1
  • Selective cerebral hematocrit decrease in the centrum semiovale after carotid artery occlusion: A PET study
    H.Yamauchi, H.Fukuyama, Y.Nagahama, Y.Katsumi, T.Hayashi, H.Okazawa, Y.Yonekura
    J Cereb Blood Flow Metab 19(1) 109-114 Jan.  1999 Refereed
    DOI:1
  • Image generation of serotonin synthesis rates using a-methyltryptophan and PET
    H.Okazawa, M.Diksic
    J Comput Assist Tomogr 22 777-785 May  1998 Refereed
    DOI:1
  • Validation of a less-invasive method for measurement of serotonin synthesis rate with alpha-[11C]methyl-tryptophan
    S.Nishizawa, M.Leyton, H.Okazawa, C.Benkelfat, S.Mzengeza, M.Diksic
    J Cereb Blood Flow Metab 18(10) 1121-1129 Jan.  1998 Refereed
    DOI:1
  • Cerebral hematocrit decreases with hemodynamic compromise in carotid artery occlusion: A PET study
    H.Yamauchi, H.Fukuyama, Y.Nagahama, Y.Katsumi, H.Okazawa
    Stroke 29(1) 98-103 Jan.  1998 Refereed
    DOI:1
  • Cochlear implant efficiency in pre- and postlingually deaf subjects - A study with H215O and PET
    H.Okazawa, Y.Naito, Y.Yonekura, N.Sadato, S.Hirano, S.Nishizawa, Y.Magata, K.Ishizu, N.Tamaki, I.Honjo, J.Konishi
    Brain 119(4) 1297-1306 Aug.  1996 Refereed
    DOI:1
  • Measurement of regional cerebral blood flow with copper-62-PTSM and a three-compartment model
    H.Okazawa, Y.Yonekura, Y.Fujibayashi, T.Mukai, S.Nishizawa, Y.Magata, K.Ishizu, N.Tamaki, J.Konishi
    J Nucl Med 37(7) 1089-1093 Jul.  1996 Refereed
    DOI:1
  • Measurement of regional cerebral plasma pool and hematocrit with copper-62-labeled HSA-DTS
    H.Okazawa, Y.Yonekura, Y.Fujibayashi, H.Yamauchi, K.Ishizu, S.Nishizawa, Y.Magata, N.Tamaki, H.Fukuyama, A.Yokoyama, J.Konishi
    J Nucl Med 37(7) 1080-1085 Jul.  1996 Refereed
    DOI:1
  • Delayed data acquisition for optimal PET activation studies with oxygen-15-water in cerebral arteriovenous malformation
    H.Okazawa, Y.Yonekura, N.Sadato, H.Lyshkow, S.Nishizawa, R.Asato, Y.Magata, K.Ishizu, N.Tamaki, J.Konishi, H.Kikuchi
    J Nucl Med 36(12) 2149-2153 Dec.  1995 Refereed
    DOI:1
  • Clinical application of 62Zn/62Cu positron generator: Perfusion and plasma pool images in normal subjects
    H.Okazawa, Y.Fujibayashi, Y.Yonekura, N.Tamaki, S.Nishizawa, Y.Magata, K.Ishizu, T.Tsuchida, N.Sadato, J.Konishi, A.Yokoyama, R.Iwata, T.Ido
    Ann Nucl Med 9(2) 81-87 May  1995 Refereed
    DOI:1
  • Clinical application and quantitative evaluation of generator-produced copper-62-PTSM as a brain perfusion tracer for PET
    Okazawa H, Yonekura Y, Fujibayashi Y, Nishizawa S, Magata Y, Ishizu K, Tanaka F, Tsuchida T, Tamaki N, Konishi J
    J Nucl Med 35(12) 1910-1915 Dec.  1994 Refereed
    DOI:1
  • Arterial spin labeling MR imaging for the clinical detection of cerebellar hypoperfusion in patients with spinocerebellar degeneration
    Ikawa M, Kimura H, Kitazaki Y, Sugimoto K, Matsunaga A, Hayashi K, Yamamura O, Tsujikawa T, Hamano T, Yoneda M, Okazawa H, Nakamoto Y
    Journal of the Neurological Sciences 394 58-62 Nov.  2018 Refereed
  • Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis
    Rahman MGM, Islam MM, Tsujikawa T, Kiyono Y, Okazawa H
    Ann Nucl Med 33(1) 14-21 Jan.  2019 Refereed
  • 18F-FLT PET/MRI for bone marrow failure syndrome-initial experience
    Tsujikawa T, Tasaki T, Hosono N, Mori T, Makino A, Kiyono Y, Zanotti-Fregonara P, Yamauchi T, Okazawa H
    Eur J Nucl Med Mol Img Re 9(1) 26 Feb.  2019 Refereed
  • No significant difference found in PET/MRI CBF values reconstructed with CT-atlas-based and ZTE MR attenuation correction
    Okazawa H, Tsujikawa T, Higashino Y, Kikuta K, Mori T, Makino A, Kiyono Y
    Eur J Nucl Med Mol Img Re 9(1) 26 Mar.  2019 Refereed
  • Altered perspective-dependent brain activation while viewing hands and associated imitation difficulties in individuals with autism spectrum disorder
    Okamoto Y, Kitada R, Miyahara M, Kochiyama T, Naruse H, Sadato N, Okazawa H, Kosaka H
    NeuroImage: Clinical 19 384-395 Apr.  2018 Refereed
  • The vertebral 3'-deoxy-3'-18F-fluorothymidine uptake predicts the hematological toxicity after systemic chemotherapy in patients with lung cancer.
    Umeda Y, Tsujikawa T, Anzai M, Morikawa M, Waseda Y, Kadowaki M, Shigemi H, Ameshima S, Mori T, Kiyono Y, Okazawa H, Ishizuka T.
    Eur Radiol. 29(7) 3908-3917 Jul.  2019 Refereed

Books etc

  • L-Arginine in Clinical Nutrition
    Arakawa K, Ikawa M, Tada H, Okazawa H, Yoneda M.
    Chapter 36: Mitochondrial cardiomyopathy and usage of L-arginine.
    Springer 2016
    978-3-319-26009-9
  • Neuroprotection and Regeneration of the Spinal Cord
    K.Uchida, H.Nakajima, H.Okazawa, H.Kimura, A.Yoshida, H.Baba
     Mar.  2014
    978-4-431-54501-9
  • Clinical PET and PET/CT
    Okazawa H and Kim YK
    14. Cerebrovascular disease and PET
    Springer Dec.  2012
    978-1-4419-0801-8 (Print) 978-1-4419-0802-5 (online)
  • Quantitation in Biomedical Imaging with PET and MRI
    H.Okazawa, H.Yamauchi, Y.Yonekura
    Measurement of arterial part of vascular volume (V0) for the evaluation of hemodynamic changes in cerebrovascular disease.
    Elsevier Jan.  2004
    444515674
  • Brain Imaging Using PET
    H.Okazawa, Y.Kishibe, K.Sugimoto, M.Takahashi, H.Yamauchi
    Delay and dispersion correction for a new coincidential radioactivity detector, Pico-Count, in quantitative PET studies.
    Academic Press, San Diego Jan.  2002

Conference Activities & Talks

  • Quantitative brain PET/MRI imaging and its clinical application
    Okazawa H
    Brain PET 2019 (The 14th International Conference on Quantification of Brain Function with PET) Jul.  2019 International Society of Cerebral Blood Flow and Metabolism
  • Comparison of MR attenuation correction methods using CT-atlas vs. zero-TE on quantitative H215O-PET/MRI
    Okazawa H, Tsujikawa T, Higashino Y, Mori T, Makino A, Kiyono Y.
    Brain PET 2019 (The 14th International Conference on Quantification of Brain Function with PET) Jul.  2019 International Society of Cerebral Blood Flow and Metabolism
  • Comparison of MR attenuation correction using CT-atlas based vs. zero-TE on quantitative 15O-water PET/MRI
    Okazawa H, Tsujikawa T, Higashino Y, Mori T, Makino M, Kiyono Y.
    The 66th Annual Meeting of Society of Nuclear Medicine and Molecular Imaging Jun.  2019 Society of Nuclear Medicine and Molecular Imaging
  • Brain PET/MRI for evaluation of neurodegenerative diseases
    Okazawa H, Ikawa M, Tsujikawa T, Kosaka H.
    The 13th Asia Oceania Congress of Nuclear Medicine and Biology May  2019 Asia Oceania Federation of Nuclear Medicine and Biology
  • Impact of scan duration on textural features in 18F-FDG PET/MR
    Tsujikawa T, Kobayashi M, Tsuyoshi H, Yamada S, Oikawa H, Yoshida Y, Okazawa H
     Oct.  2017
  • PET neuroimaging for oxidative stress based on mitochondrial dysfunction in neurodegenerative diseases
    Ikawa M, Okazawa H, Tsujikawa T, Nakamoto Y, Yoneda M
    World Congress of Neurology Sep.  2017
  • Molecular brain imaging evaluates the pathophysiology of stroke-like episodes in MELAS
    Yoneda M, Ikawa M, Tsujikawa T, Kimura H, Okazawa H
    World Congress of Neurology Sep.  2017
  • Development of right-hemispheric dominance of human inferior parietal lobule associated with proprioceptive illusory awareness
    Naito E, Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M
    The 40th Annual Meeting of the Japan Neuroscience Society Jul.  2017
  • Development of human right inferior fronto-parietal cortices associated with self-face recognition
    Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E
    The 40th Annual Meeting of the Japan Neuroscience Society Jul.  2017
  • Predictive value of 3'-deoxy-3'-18F-fluorothymidine uptake in colorectal cancer treated with proton irradiation under hypoxic condition.
    Kiyono Y, Murata M, Makino A, Kume K, Mori T, Asai T, Okazawa H
    The 64th Annual Meeting of The Society of Nuclear Medicine Jun.  2017
  • 18F-FES and 18F-FDG PET/MR imaging of gynecologic tumors:Initial experience in 5 cases
    Tsujikawa T, Tsuyoshi H, Yamada S, Shinagawa A, Chino Y, Mori T, Kurokawa T, Kiyono Y, Yoshio Y, Okazawa H
    The 64th Annual Meeting of The Society of Nuclear Medicine Jun.  2017
  • Clinical evaluation of the statistical images for the cerebral blood flow SPECT using common normal database constructed with CT based-attenuation correction and resolution compensation: a multicenter study.
    Inui Y, Ichihara T, Uno M, IshiguroM, Ota S, Ito K, Yamazaki T, Kato K, Sakuma H, Okazawa H, Toyama H.
    The 64th Annual Meeting of The Society of Nuclear Medicine Jun.  2017
  • Measurement of cerebral blood flow using H215O PET/MRI with a noninvasive method.
    Okazawa H, Higashino Y, Tsujikawa T, Mori T, Arishima H, Kiyono Y, Kikuta K.
    The 64th Annual Meeting of The Society of Nuclear Medicine Jun.  2017
  • Development of a new fluorine-18 labelled probe targeting norepinephrine transporter
    Makino A, Martinez ME, Okazawa H, Kiyono Y
    22nd International Symposium on Radiopharmaceutical Sciences(ISRS2017) May  2017
  • Dopaminergic neuronal oxidative stress is increased with disease progression in patients with Parkinson’s disease: A study with PET and SPECT
    Ikawa M, Okazawa H, Neishi H, Kitazaki Y, Tsujikawa T, Kikuta K, Nakamoto Y, Yoneda M
    Annual Meeting of American Academy of Neurology Apr.  2017
  • Assessment of intratumor heterogeneity in mesenchymal uterine tumor by FDG-PET/CT texture analysis.
    Tsujikawa T, Yamamoto M, Shono K, Yamada S, Kimura H, Okazawa H, Yoshida Y
     Apr.  2017
  • Dopaminergic neuronal oxidative stress is increased with disease severity in patients with Parkinson's disease: A study with PET and SPECT
    Ikawa M, Okazawa H, Neishi H, Kitazaki Y, Tsujikawa T, Kikuta K, Nakamoto Y, Yoneda M
    28th International Symposium on Cerebral Blood Flow. Metabolism and Function and 13th Conference on Quantification of Brain Function with PET Apr.  2017
  • Measurement of cerebral blood flow with H215O PET/MRI.
    Okazawa H, Tsujikawa T, Higashino Y, Arishima H, Mori T, Kiyono Y, Kikuta K.
    Brain & Brain PET 2017 Apr.  2017
  • Estimation of noninvasive arterial input in brain O-15 water PET study
    Islam MM, Tsujikawa T, Mori T, Kiyono Y, Okazawa H
    The 56th Annual Scientific Meeting of the Japanese Society of Nuclear Medicine Nov.  2016 The Japanese Society of Nuclear Medicine
  • PET Imaging of Estrogen Receptors in Metastatic Breast Cancer
    Maeda H, Higashi M, Tsuchida T, Mori T,Tsujikawa T, Imamura Y, Okazawa H, Goi T
     Oct.  2016
  • Distinct neural representation of perspective of hand in the lateral occipito-temporal cortex
    Okamoto Y, Kitada R, Arai S, Kochiyama T, Ishikawa S, Sadato N, Okazawa H, Kosaka H
    The 39th Annual Meeting of the Japan Neuroscience Society Jul.  2016
  • Clinical benefits of precise delay correction for CBF measurement in O-15 water PET study.
    Islam MM, Tsujikawa T, Mori T, Kiyono Y, Okazawa H.
    The 63th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging Jun.  2016 Society of Nuclear Medicine
  • Development of a PET probe detecting tumors, which are responsive to gefitinib treatment
    Makino A, Miyazaki A, Kimura H, Hirata M, Ohmomo Y, Nishii R, Okazawa H, Kiyono Y, Ono M, Saji H
    Society of Nuclear Medicine and Molecular Imaging 2016 Annual Meeting Jun.  2016 Society of Nuclear Medicine
  • Predictive value of 3'-deoxy-3'-18F-fluorothymidine uptake in colorectal cancer treated with carbon ion irradiation under hypoxic condition.
    Kiyono Y, Kume K, Mori T, Okazawa H
    The 63th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging Jun.  2016
  • Assessment of intratumor heterogeneity on FDG-PET/CT for differentiating between uterine sarcoma and leiomyoma
    Tsujikawa T, Yamamoto M, Chino Y, Shinagawa A, Tsuchida T, Kurokawa T, Yoshida Y, Okazawa H
    The 63th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging Jun.  2016 Society of Nuclear Medicine
  • Functional images predict prognosis of uterine sarcoma patient: Estrogen receptor expression combined with FDG PET
    Tsujikawa T, Yamamoto M, Chino Y, Shinagawa A, Tsuchida T, Mori T, Kurokawa T, Kiyono Y, Yoshida Y, Okazawa H
    The 63th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging Jun.  2016 Society of Nuclear Medicine
  • Evaluation of cerebral oxidative stress in patients with ALS using 62Cu-ATSM PET
    Ikawa M, Okazawa H, Matsunaga A, Yamamura O, Hamano T, Kiyono Y, Nakamoto Y, Yoneda M
     May  2016
  • Micelle type dual imaging probe for positron and near-infrared fluorescence imagings
    A.Makino, A.Tomoike, H.Kimura, M.Ono, H.Okazawa, Y.Kiyono, H.Saji
    The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015) Dec.  2015
  • Evaluation of in vivo dynamics of the polymeric micelle by using two different radioisotope modification approaches
    Makino A, Tomoike A, Ono M, Kiyono Y, Okazawa H, Saji H
    The 9th Japan-China Joint Seminar on Radiopharmaceutical Chemistry Nov.  2015
  • Development of a low cost multipurpose synthesis system for F-18 PET tracers
    T.Mori, M.Kunieda, Y.Fujibayashi, H.Okazawa, Y.Kiyono:
    Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry (JCSRC2015). Nov.  2015
  • Pixel wise delay correction for precise PET measurement
    MM.Islam, H.Okazawa
     Oct.  2015
  • Evaluation of nigrostriatal oxidative stress intensity in patients with Parkinson’s disease using [Cu-62]ATSM PET and FP-CIT SPECT.
    H.Okazawa, M.Ikawa, T.Tsujikawa , T.Mori, A.Makino, Y.Kiyono, M.Yoneda
    Annual Congress of the European Association of Nuclear Medicine (EANM2015)  Oct.  2015
  • PET probe detecting acquired drug resistance against EGFR targeted molecular therapy
    Makino A, Miyazaki A, Tomoike A, Kimura H, Hirata M, Ohmomo Y, Ono M, Okazawa H, Kiyono Y, Saji H
    Annual Congress of the European Association of Nuclear Medicine 2015 Oct.  2015
  • Shared right inferior fronto-parietal substrates for corporeal awareness and self-identification.
    T.Morita, DN.Saito, M.Ban, K.Shimada, Y.Okamoto, H.Kosaka, H.Okazawa, M.Asada, E.Naito
    The 21st Annual Meeting of the Organization for Human Brain Mapping.  Jun.  2015
  • Evaluation of Striatal oxidative stress in Parkinson’s disease using [Cu-62]ATSM PET.
    H.Okazawa, M.Ikawa, T.Tsujikawa, T.Mori, Y.Kiyono, M.Yoneda
    Brain & Brain PET 2015 (XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function) Jun.  2015
  • Prediction of head and neck cancer outcome evaluated by tumor redox status using 62Cu-ATSM PET.
    T.Tsujikawa, S.Asahi, M.Oh, T.Mori, Y.Kiyono, H.Okazawa
    The 62th Annual Meeting of The Society of Nuclear Medicine Jun.  2015
  • Predictive value of early stage uptake of 3'-deoxy-3'-18F-fluorothymidine in colorectal cancer treated with charged particle irradiation.
    Y.Kiyono, C.Lin, K.Kume, T.Mori, ME.Martinez, H.Okazawa
    62nd Annual Meeting of Society of Nuclear Medicine Jun.  2015
  • Development of a low cost multipurpose system for F-18 labeled PET probe synthesis
    T.Mori, M.Kunieda, H.Okazawa, Y.Kiyono
    The 62nd Annual Meeting of the Society of Nuclear Medicine Jun.  2015
  • Male brain is more affected by autism spectrum traits than female
    M.Jung, DN.Saito, A.Tomoda, H.Okazawa, Y.Wada, H.Kosaka
    21st Annual Meeting of the Organization for Human Brain Mapping.(OHBM2015) Jun.  2015
  • Assessment of hormone sensitivity in uterine leiomyoma patients using 18F-FES PET
    T.Tsujikawa, Y.Chino, A.Shinagawa, M.Yamamoto, A.Makino, T.Mori, T.Kurokawa, Y.Kiyono, Y.Yoshida, H.Okazawa
    SNMMI 2015 Annual Meeting Jun.  2015
  • Evaluation of a new precursor for radiosynthesis of 2-deoxy-2-[18F]fluoroacetamido-D-glucopyranose
    ME. Martinez, Y.Tokunaga, T.Mori, A.Makino, H.Okazawa, Y.Kiyono
    10th Annual Meeting of Japanese Society for Molecular Imaging May  2015
  • Hypoxic intensity and tumor burden measured by 62Cu-ATSM-PET in head and neck cancer patients: Comparison of prognostic prediction with FDG-PET
    T.Tsujikawa, S.Asahi, M.Oh, Y.Sato, T.Mori, Y.Kiyono, S.Fujieda, H.Kimura, H.Okazawa
    第74回日本医学放射線学会学術集会 Apr.  2015
  • Pathophysiological decrease in the regional cerebral blood flow in Hashimoto's encephalopathy: A multiple-case SPECT study.
    M.Ikawa, T.Muramatsu, K.Sugimoto, A.Matsunaga, O.Yamamura, T.Hamano, Y.Nakamoto, H.Okazawa, M.Yoneda
    American Academy of Neurology (AAN) Annual Meeting 2015 Apr.  2015
  • Imaging oxidative stress
    H.Okazawa
     Mar.  2015
  • Effect of burst stimulation by high frequency biphasic square-wave pulse on cortical perfusion after stroke: A pilot study
    O. Yamamura, T. Kamisawa, T.Hamano, Y.Nakamoto, M. Kubota, C. Igarashi, Y.Watabe, S.Shimada, H.Okazawa, R.Kato, H.Yokoi, k.Uchida, H.Baba
     Nov.  2014
  • Increased cerebral oxidative stress in amyotrophic lateral sclerosis: a 62Cu-ATSM PET study
    K.Miyazaki, M.Ikawa, T.Tsujikawa, T.Mori, T.Hamano, Y.Nakamoto, Y.Kiyono, H.Okazawa, M.Yoneda
    The 11th Conference of Asian Society for Mitochondrial Research and Medicine Nov.  2014
  • Hypoxic volume measurement using Cu-ATSM PET may be a predictive index for prognosis of advanced head-and-neck cancers: Comparison with FDG-PET.
    H.Okazawa, T.Tsujikawa, M.Oh, Y.Sato, T.Mori, S.Fujieda, Y.Kiyono
     Sep.  2014
  • Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits
    M.Jung, H.Kosaka, DN.Saito, M.Ishitobi, T.Munesue T, A.Tomoda, Y.Wada, H.Okazawa, T.Iidaka
     Sep.  2014
  • Comparison of target sites for exploring an effective nano-irradiation therapy using Auger electron.
    Y.Kiyono, T.Mori, T.Asai, Y.Yoshii, H.Okazawa
     Sep.  2014
  • Predictive value of early stage uptake of 18F-FLT in colorectal cancer treated with charged particle radiotherapies
    C.Lin, K.Kume, T.Mori, M.E.Martinez, H.Okazawa, Y.Kiyono
     Sep.  2014
  • Evaluation of cerebral oxidative stress in amyotrophic lateral sclerosis using 62Cu-ATSM PET.
    H.Okazawa, M.Ikawa, T.Tsujikawa, A.Matsunaga, T.Mori, Y.Kiyono, M.Yoneda
     Jun.  2014
  • Volume-based hypoxic parameters of 62Cu-ATSM PET as prognostic indicators in head and neck cancer
    T.Tsujikawa, S.Asahi, M. Oh, Y. Sato, T.Tsuchida, A. Makino, T.Mori, Y.Kiyono, S.Fujieda, H.Okazawa
    The 61st Annual Meeting of The Society of Nuclear Medicine Jun.  2014
  • Functional connectivity in default mode network predicts autism spectrum traits?
    Jung M, Kosaka H, Saito DN, Ishitobi M, Morita T, Inohara K, Sasaki A, Asano M, Arai S, Masuya Y, Munesue T, Tomoda A, Wada Y, Sadato N, Okazawa H, Iidaka T
     Jun.  2014
  • Evaluation of target sites for nano-irradiation therapy with Auger electron.
    Y.Kiyono, T.Mori, T.Asai, Y.Yoshii, H.Okazawa
     Jun.  2014
  • Development of a low cost flexible module system for F-18 labeled PET tracer production
    T.Mori, K.Takaki, Y.Fujibayashi, H.Okazawa, Y.Kiyono
     Jun.  2014
  • In vitro and in vivo evaluation of 3'-deoxy-3'-18F-fluorothymidine for monitoring early therapeutic responses to charged particle radiotherapies
    C.Lin, K.Kume, T.Mori, M.E.Martinez, T.Takata, H.Okazawa, Y.Kiyono
     May  2014
  • Preclinical assessment of early therapeutic effect of sunitinib on renal cell carcinoma using 18F-fluorothymidine positron emission tomography in a xenograft model
    N.Oyama, Y.Hasegawa, K.Tsuchiyama, M.Taga, H.Ito, H.Akino, H.Okazawa, O.Yokoyama
     May  2014
  • Pathophysiological decrease in the regional cerebral blood flow in pure autonomic failure with Lewy body
    T.Kamisawa, M.Ikawa, Y.Saito, T.Muramatsu, A.Matsunaga, O.Yamamura, T.Hamano, Y.Nakamoto, S.Murayama, H.Okazawa, M.Yoneda
    2014 AAN May  2014
  • Increased cerebral oxidative stress in amyotrophic lateral sclerosis: a 62Cu-ATSM PET study
    M.Ikawa, H.Okazawa, T.Tsujikawa, T.Muramatsu, T.Kishitani, T.Kamisawa, A.Matsunaga, O.Yamamura, T.Mori, T.Hamano, Y.Kiyono, Y.Nakamoto, M.Yoneda
    2014 AAN May  2014
  • Assessing tumor hypoxia in head and neck cancer by PET with 62Cu-ATSM
    辻川 哲也, 佐藤 義高, 呉 明美, 土田 龍郎, 藤枝 重治, 岡沢 秀彦
     Apr.  2014
  • Insulin Resistance Impairs Cardiac Efficiency in Patients with Acute Myocardial Infarction
    Y.Fukuoka, M.Koike, Y.Sato, K.Hisazaki, J.Yamaguchi, A.Fujii, E.Ikeda, H.Ikeda, T.Morishita, T.Sato, K.Ishida, K.Kaseno, K.Arakawa, N.Amaya, H.Uzui, J-D.Lee, A.Nakano, T.Kudo, H.Okazawa, H.Tada
     Mar.  2014
  • Reverse blood flow?glucose metabolism mismatch indicates preserved oxygen metabolism in patients with revascularized myocardial infarction
    Y.Fukuoka, A.Nakano, H.Uzui, T.Kudo, J-D.Lee, H.Okazawa, H.Tada
     Mar.  2014
  • Evaluation of radiobrominated (2S,αS)-2-(α-(2-bromophenoxy)benzyl)morpholine as an imaging probe for brain norepinephrine transporter
    Y.Kiyono, T.Mori, Miguel Martinez, T.Asai, H.Okazawa
     Mar.  2014
  • Imaging of changes in norepinephrine transporter in depression model rats with a radiobrominated (2S,αS)-2-(α-(2-bromophenoxy)benzyl)morpholine.
    M.Kashiwahara, N.Omata, T.Mizuno, T.Asai, H.Okazawa, Y.Kiyono
     Mar.  2014
  • Evaluation of target sites for nano-irradiation therapy with Auger electron.
    Y.Kiyono, T.Mori, T.Asai, Y.Yoshii, H.Okazawa
     Mar.  2014
  • PET Imaging of Estrogen Receptors in Metastatic Breast Cancer Patients
    H.Maeda, M.Nakazawa, T.Tsuchida, Y.Imamura, T.Mori, T.Tsujikawa, A.Yamaguchi, H.Okazawa
     Mar.  2014
  • Regional changes in cerebral oxidative stress of neurodegenerative disease evaluated by 62Cu-ATSM PET
    M.Yoneda, M. Ikawa, T.Tsujikawa, A.Matsunaga, T.Mori, Y.Kiyono, H.Okazawa
     Mar.  2014
  • Developmental changes of attention ability in children and adolescents.
    D.N.Saito, H.Yanaka, T.Fujii, H.Kosaka, T.Muramatsu, K.Matsumura, M.Sato, H.Okazawa
     Mar.  2014
  • In vitro and in vivo evaluation of 3'-deoxy-3'-18F-fluorothymidine for monitoring early therapeutic responses to charged particle radiotherapies.
    C.Lin, K.Kume, T.Mori, M.E.Martinez, T.Takata, H.Okazawa, Y.Kiyono
     Mar.  2014
  • Effect of the pixel-by-pixel delay correction on cerebral blood flow in H215O PET study using 2 compartment model
    M.M.Islam, H.Okazawa
     Mar.  2014
  • Usefulness of total lesion glycolysis in FDG-PET studies for predicting the prognosis of ovarian cancer patients.
    M.Yamamoto, T.Kurokawa, Tetsuya Tsujikawa, Y.Kiyono, H.Okazawa, Y.Yoshida
     Mar.  2014
  • Changes in cerebral glucose metabolism induced by non-steroidal anti-inflammatory drug evaluated by dynamic positron autoradiography (dPAT) with rat brain slices.
    T.Asai, T.Katsuno, H.Okazawa
     Mar.  2014
  • Regional changes in cerebral oxidative stress evaluated by 62Cu-ATSM PET in patients with amyotrophic lateral sclerosis.
    M.Yoneda, M. Ikawa, T.Tsujikawa, A.Matsunaga, T.Mori, Y.Kiyono, H.Okazawa
     Mar.  2014
  • Pathophysiological decrease in the regional cerebral blood flow in Hashimoto’s encephalopathy: a multiple-case SPECT study.
    T.Muramatsu, M. Ikawa, M.Yoneda, K.Sugimoto, A.Matsunaga, O.Yamamura, T. Hamano, H.Okazawa, Y.Nakamoto
     Mar.  2014
  • The effect of functional electrical stimulation (FES) on H2[15O] PET in the post-stroke patients.
    T.Kamisawa, O.Yamamura, M.Kubota, C.Igarashi, Tetsuya Tsujikawa, K.Uchida, M.Suzuki, R.Kato, H.Yokoi, T. Hamano, Y.Nakamoto, H.Okazawa
     Mar.  2014
  • Quantitative evaluation of cerebral blood flow using pulsed continuous arterial spin labeling (pCASL): Comparison with quantitative SPECT.
    M.Isozaki, H.Okazawa, A.Tada, R.Kitai, H.Kimura, K.Kikuta
     Mar.  2014
  • Prognostic value of 18F-FDG and 18F-FLT PET imaging in patients with advanced non-small cell lung cancer.
    Y.Umeda, T.Tsuchida, Miwa Morikawa, M.Anzai, S.Ameshima, H.Okazawa, T.Ishizaki, T.Ishizuka
     Mar.  2014
  • Prognostic value of dual-time-point 18F-FDG PET in fibrotic idiopathic interstitial pneumonia.
    Y.Umeda, Y.Demura, T.Tsuchida, Miwa Morikawa, M.Anzai, S.Ameshima, H.Okazawa, T.Ishizaki, T.Ishizuka
     Mar.  2014
  • Depressive mood modulates hippocampal CA1 during a pattern separation task in healthy subjects: a functional MRI study.
    T.Fujii, D.N.Saito, H.Kosaka, H.Yanaka, H.Okazawa
     Mar.  2014
  • Neural substrates of contingency detection for self and other in individuals with autism spectrum disorder: an fMRI study.
    A.T.Sasaki, H.Kosaka, D.N.Saito, K.Inohara, M.Jung, R.Kitada, H.Okazawa, N.Sadato
     Mar.  2014
  • Being observed do not modulate self-conscious emotion in autism spectrum disorders.
    T.Morita, H.Kosaka, D.N.Saito, T.Fujii, M.Ishitobi, T.Munesue, K.Inohara, H.Okazawa, R.Kakigi, N.Sadato
     Mar.  2014
  • Usefulness of total lesion glycolysis in FDG-PET studies for predicting the prognosis of ovarian cancer patients
    M.Yamamoto, T.Kurokawa, T.Tsujikawa, Y.Kiyono, H.Okazawa, Y.Yoshida
    International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology(Fukui2014) Mar.  2014
  • Disappearance of depression-related behaviors by extension of duration of social isolation; is mania beyond depression?
    N.Omata, T.Mizuno, H.Mitsuya, K.Mita, H.Okazawa, Y.Wada, Y.Kiyono
     Mar.  2014
  • In vitro and in vivo evaluation of 3'-deoxy-3'-18F-fluorothymidine for monitoring early therapeutic responses to charged particle radiotherapies
    C.Lin, K.Kume, T.Mori, M.E. Martinez, T.Takata, H.Okazawa, Y.Kiyono
     Mar.  2014
  • Evaluation of new precursors for radiosynthesis of 2-deoxy-2-[18F]fluoroacetamido-D-glucopyranose
    M.E.Martinez, Y.Tokunaga, T.Mori, S.Noriki, K.Inai, T.Ido, H.Okazawa, Y.Kiyono
     Mar.  2014
  • Fully automated production of [18F]fluoroacetate on a compact FDG synthesizer
    T.Mori, R.Arai, D.Blampain, T.Kosuga, T.Asai, Y.Fujibayashi, H.Okazawa, Y.Kiyono
    International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology Mar.  2014
  • Development of a flexible synthesis module system for F-18 labeled PET tracer
    T.Mori, T.Takaki, Y.Fujibayashi, T.Asai, H.Okazawa, Y.Kiyono
     Mar.  2014
  • Developmental changes of attention ability in children and adolescents.
    D.N.Saito, H.Yanaka, T.Fujii, H.Kosaka, T.Muramatsu, K.Matsumura, M.Sato, H.Okazawa
     Mar.  2014
  • Default mode network in autism spectrum disorder (1) -Differences of functional connectivities compared individuals with typical development-
    H.Kosaka, M.Jung, D.N.Saito, M.Ishitobi, T.Morita, K.Inohara, A.Sasaki, M.Asano, S.Arai, Y.Masuya, T.Munesue, A.Tomoda, Y.Wada, N.Sadato, H.Okazawa, T.Iidaka
     Mar.  2014
  • Default mode network in autism spectrum disorder (2) -Strength of functional connectivities in default mode network predicts autism spectrum traits?-
    M.Jung, H.Kosaka, D.N.Saito, M.Ishitobi, T.Morita, K.Inohara, A.Sasaki, M.Asano, S.Arai, Y.Masuya, T.Munesue, A.Tomoda, Y.Wada, N.Sadato, H.Okazawa, T.Iidaka
     Mar.  2014
  • Crossedcellebellar diaschisis in clinically diagnosed corticobasal degeneration
    T.Hamano, A.Matsunaga, T.Muramatsu, T.Kishitani, S.Enomoto, K.Yamate, N.Shirafuji, M. Ikawa, T.Tsuchida, T.Tsujikawa, T.Kudo, H.Okazawa, M.Yoneda, M.Kuriyama, Y.Nakamoto
     Mar.  2014
  • Feasibility of pulsed continuous arterial spin labeling (pCASL) in quantitative evaluation of cerebral blood flow: Comparison with quantitative SPECT and PET
    M.Isozaki, A.Tada, Tetsuya Tsujikawa, H.Kimura, K.Kikuta, H.Okazawa
     Jan.  2014
  • Which target site is effective for nano-irradiation therapy using Auger electron?
    Y.Kiyono, T.Mori, T.Asai, Y.Yoshii, H.Okazawa
     Jan.  2014
  • HPLC and HPLC-ESI-MS/MS methods for the determination of 2-acetamido-2-deoxy-D-glucopyranose analogues
    M.E.Martinez, Y.Tokunaga, T.Mori, A.Makino, S.Noriki, K.Inai, H.Okazawa, Y.Kiyono
     Jan.  2014
  • The Impact of L-arginine administration in patients with mitochondrial cardiomyopathy evaluated by 11C-acetate-PET
    Arakawa K, Ikawa M, Tada H, Okazawa H, Yoneda M
     Jan.  2014
  • The Impact of L-arginine administration in patients with mitochondrial cardiomyopathy evaluated by 11C-acetate-PET
    K.Arakawa, M.Ikawa, H.Tada, H.Okazawa, M.Yoneda
    5th World Congress on Targeting Mitochondria Jan.  2014
  • PET imaging of cerebral oxidative stress in neurodegenerative disorders
    M.Yoneda, M.Ikawa, T.Tsujikawa, T.Mori, T.Hamano, Y.Nakamoto, Y.Kiyono, H.Okazawa
    5th World Congress on Targeting Mitochondria Jan.  2014
  • Cu-ATSM uptake may predict prognosis after treatment in advanced head-and-neck cancers: Evaluation of resistant hypoxic tissue with tumor-to-muscle ratio
    Y.Sato, M.Oh, Y.Kimura, Y.Kiyono, T.Mori, S.Fujieda, H.Okazawa
     Dec.  2013
  • Evaluation of Staging and Response to Chemotherapy with Whole-body Diffusion-weighted Magnetic Resonance Imaging in Malignant Lymphoma Patients: A Comparison with FDG-PET
    Kazunobu Tsuji, Tatsuro Tsuchida, Shinji Kishi, Hidehiko Okazawa, Hirohiko Kimura
     Dec.  2013
  • Prognostic value of dual-time point 18F-FDG PET in fibrotic idiopathic interstitial pneumonia
    Y. Umeda, Y. Demura, C. Honjo, Y. Sumida, M. Morikawa, M. Anzal, S. Ameshima, T. Tsuchida, H. Okazawa, T. Ishizaki, T. Ishizuka
    ERS ANNUAL CONGRESS 2013 Sep.  2013
  • Beneficial early effects of statin treatment on coronary microvascular dysfunction and left ventricular remodeling in patients with acute anterior myocardial infarctions
    K.Ishida, M.Koike, H.Uzui, N.Amaya, K.Arakawa, K.Kaseno, T.Morishita, H.Okazawa, J-D.Lee, H.Tada
     Sep.  2013
  • Quantitative Evaluation of Cerebral Blood Flow Using Pulsed Continuous Arterial Spin Labeling Technique Compared with Imp-spect
    S.Yamada, M.Isozaki, A.Tada, H.Arai, H.Takeuchi, H.Okazawa, H.Kimura, K.Kikuta
    15th World Congress of Neurosurgery Sep.  2013
  • Magnetic resonance assessment of diffuse lung injury in rats
    M.Morikawa, Y.Umeda, M.Anzai, Y.Demura, C.Honjo, M.Kadowaki, Y.Sumida, S.Ameshima, T.Ishizaki, H.Uematsu, H.Kimura, H.Okazawa, T.Ishizuka
     Sep.  2013
  • Tumor-to-muscle ratio of Cu-ATSM uptake may reflect outcome of treatment in head-and-neck cancers: Predictability of resistant hypoxic tissue.
    Y.Sato, M.Oh, Y.Kimura, Y.Kiyono, T.Mori, S.Fujieda, H.Okazawa
     Jun.  2013
  • Imaging of changes in norepinephrine transporter in depression model rats with a radiobrominated (2S, αS)-2-(α-(2-bromophenoxy)benzyl)morpholine.
    Y.Kiyono, M.Kashiwahara, N.Omata, T.Mizuno, T.Mori, T.Asai, H.Okazawa
    The 60th Annual Meeting of The Society of Nuclear Medicine Jun.  2013
  • Predictability of later developed relapse in endometrial carcinoma in young women with functional imaging parameters of FES/FDG SUV ratio after hormone treatment.
    Y.Yoshida, T.Kurokawa, H.Tsuyoshi, A.Shinagawa, Y.Kiyono, T.Mori, H.Okazawa
     Jun.  2013
  • The development of attentional network during childhood and adult: an fMRI study.
    D.N.Saito, H.Yanaka, T.Kochiyama, T.Fujii, H.Kosaka, T.Muramatsu, T.Shimada, K.Matsumura, M.Sato, H.Okazawa
     Jun.  2013
  • Development of attentional networks: Voxel-Based Morphometry study
    T.Fujii, D.N.Saitou, H.T.Yanaka, H.Kosaka, T.Muramatsu, H.Okazawa
     Jun.  2013
  • Predictability of later developed relapse in endometrial carcinoma in young women with functional imaging parameters of FES/FDG SUV ratio after hormone treatment.
    Y.Yoshida, H.Okazawa, A.Shinagawa, Y.Kiyono, T.Mori, T.Kurokawa
    2013 ASCO Annual Meeting Jun.  2013
  • Effects of the combination of zinc deficiency and social isolation on depression-like state in rats
    T.Mizuno, N.Omata, T.Murata, H.Mitsuya, N.Maruoka, K.Mita, Y.Kiyono, H.Okazawa, Y.Wada
     Jun.  2013
  • Effect of nonsteroidal anti-inflammatory drug celecoxib on cerebral glucose metabolism in rat brain slices as measured by dynamic positron autoradiography
    T.Asai, S.Fukumoto, W.Wang, H.Okazawa
     May  2013
  • Depressive mood modulates anterior lateral CA1 during a pattern separation task in healthy individuals: a functional MRI study
    T.Fujii, D.N.Saito, H.Yanaka, H.Kosaka, H.Okazawa
     May  2013
  • Feasibility of using pulsed continuous arterial spin labeling technique for quantitative evaluation of cerebral blood flow.
    M.Isozaki, H.Okazawa, A.Tada, H.Takeuchi, H.Kimura, K.Kikuta
     May  2013
  • Fully automated production of [18F]fluoroacetate on IBA Synthera platform
    T.Mori, R.Arai, D.Blampain, C.Gameiro-Paris, T.Kosuga, T.Asai, Y.Fujibayashi, H.Okazawa, Y.Kiyono
     May  2013
  • Early Statin Treatment can Attenuate Left Ventricular Remodeling and Improve Coronary Microvascular Function in Acute, Anterior Myocardial Infarctions
    K.Ishida, H.Uzui, N.Amaya, K.Arakawa, T.Sato, Y.Fukuoka, T.Morishita, H.Ikeda, K.Murakami, C.Maeda, M.Koike, Y.Sato, K.Hisazaki, J.Yamaguchi, H.Okazawa, J-D.Lee, H.Tada
     Mar.  2013
  • Predictability of treatment effects with Cu-ATSM PET in head-and-neck cancers: Comparison with FDG-PET.
    H.Okazawa, Y.Kimura, M.Oh, Y.Kiyono, T.Mori, S.Fujieda
     Sep.  2012
  • Feasibility of 62Cu-ATSM PET and its predictability of treatment effects in head-and-neck cancers: Comparison of 62Cu-ATSM and 18F-FDG PET.
    佐藤 義高, 呉 明美, 木村 有一, 清野 泰, 森 哲也, 藤枝 重治, 岡沢 秀彦
    Japan Advanced Molecular Imaging Program Symposium 2012 Aug.  2012
  • In vitro imaging of over-reduction state (oxidative stress) in cells with mitochondrial dysfunction using PET radiopharmaceutical Cu-ATSM
    M.Ikawa, Y.Yoshii, Y.Nakamoto, H.Okazawa, Y.Fujibayashi, M.Yoneda
     Aug.  2012
  • Is it easy for autistic people to think about an autistic character’s behavior in a story? The effect of similarity between readers and characters in recognition
    H.Komeda, H.Kosaka, D.N.Saito, K.Inohara, T.Munesue, H.Okazawa
     Jul.  2012
  • Evaluation of radiobromine-labeled (2S,αS)-2-(α-(2-bromophenoxy)benzyl)morpholine as an imaging probe for brain norepinephrine transporter.Evaluation of radiobromine-labeled (2S,αS)-2-(α-(2-bromophenoxy)benzyl)morpholine as an imaging probe for brain norepinephrine transporter.
    Y.Kiyono, T.Mori, T.Asai, Y.Fujibayashi, H.Okazawa
     Jun.  2012
  • Evaluation of 5-[77Br]bromo-4’-thio-2’-deoxyuridine as a radiopharmaceutical for DNA targeted nanoirradiation therapy.
    Y.Kiyono, R.Ikeda, T.Mori, Y.Yoshii, Y.Fujibayashi, H.Okazawa
     Jun.  2012
  • Predictability of 62Cu-ATSM uptake to evaluate resistant hypoxic tissue and effects of treatment in head-and-neck cancers
    H.Okazawa, Y.Kimura, Y.Kiyono, T.Mori, S.Fujieda
     Jun.  2012
  • Developement of an automatic Copper-62 ATSM preparation module in asceptic condition.
    T.Mori, K.Takaki, Y.Kiyono, Y.Fujibayashi, H.Okazawa
     Jun.  2012
  • Basic research on the development of parenthood: Comparison between mothers and fathers of the effects of listening to a crying infant on brain activation
    A.Sasaki, H.Kosaka, Y.Namizaki, K.Matuki, H.Okazawa
     Jun.  2012
  • Evaluation of radiobromine-labeled (2S,αS)-2-(α-(2-bromophenoxy)benzyl)morpholine as an imaging probe for brain norepinephrine transporter.Evaluation of radiobromine-labeled (2S,αS)-2-(α-(2-bromophenoxy)benzyl)morpholine as an imaging probe for brain norepinephrine transporter.
    Y.Kiyono, T.Mori, T.Asai, Y.Fujibayashi, H.Okazawa
     Jun.  2012
  • Self-Related Representation in Individuals with High-Functioning Autism
    H. Komeda, H. Kosaka, D. N. Saito, Y. Mano, T. Fujii, H. Yanaka, T. Munesue, H. Okazawa
    2012 International Meeting for Autism Research May  2012
  • In Vitro and In Vivo Imaging of Over-reduction States (Oxidative Stress) in MELAS using PET Radiopharmaceutical Cu-ATSM
    M.Yoneda, M.Ikawa, Y.Yoshii, Y.Nakamoto, Y.Fujibayashi, H.Okazawa
     Apr.  2012
  • PET Imaging of Striatal Oxidative Stress in Patients with Parkinson's Disease using 62Cu-ATSM
    M.Ikawa, H.Okazawa, T.Kudo, Y.Nakamoto, Y.Fujibayashi, M.Yoneda
     Apr.  2012
  • A Reverse Flow-Glucose Metabolism Mismatch Pattern Indicates Preserved Fatty Acid and Oxygen Metabolism in Patients with AMI
    Y.Fukuoka, A.Nakano, H.Uzui, Y. Mitsuke, T. Geshi, H.Okazawa, J-D.Lee
     Mar.  2012
  • Relationship between effects of treatment and Cu-ATSM uptake in head-and-neck cancers: Predictability of resistant hypoxic tissue in cancers.
    H.Okazawa, Y.Kimura, M.Oh, Y.Kiyono, T.Mori, S.Fujieda
     Jan.  2012
  • Development of attentional networks: Volume-Based Morphometry study
    T. Fujii, D. N. Saito, H. T. Yanaka, H. Kosaka, T. Muramatsu, H. Okazawa
    Neuroscience 2012 Jan.  2012
  • Social behaviors of autistic disorder are improved by long-term oxytocin administration: A case of 16-year-old girl.
    H. Kosaka, T. Munesue, M. Ishitobi, M. Asano, D. N. Saito, T.Fujii, M. Omori, A. Tomoda, H. Okazawa, Y. Wada
    Neuroscience 2012 Jan.  2012
  • Evaluation of 5-[77Br]bromo-4’-thio-2’-deoxyuridine as a radiopharmaceutical for DNA targeted internal radiation therapy.
    Y.Kiyono, R.Ikeda, T.Mori, Y.Yoshii, T.Asai, Y.Fujibayashi, H.Okazawa
     Jan.  2012
  • Relationship Between 11C-acetate Uptake and the Expression of Fatty Acid Synthase in Renal Cell Carcinoma: A Preliminary Clinical Study.
    N.Oyama, N.Takahara, Y.Hasegawa, Y.Miwa, H.Akino, H.Okazawa, O.Yokoyama
     Jan.  2012
  • Oxytocin effect in young males with autism spectrum disorders: An eye-tracking study
    H.Kosaka, T.Munesue, D.N.Saito, T.Fujii, H.Yanaka, M.Ishitobi, M.Asano, K.Narita, T.Murata, M.Omori, H.Okazawa, N.Sadato, Y.Wada
     Dec.  2011
  • Cerebrovascular Disease and O-15 PET
    H.Okazawa
     Nov.  2011
  • Encoding related activity in dentate gyrus is associated with subjective mood: A functional MRI study
    T.Fujii, D.N.Saito, H.T.Yanaka, H.Kosaka, H.Oikawa, H.Okazawa
    Neuroscience 2011 Nov.  2011
  • Oxytocin facilitates eye contact in young males with autism spectrum disorders
    H.Kosaka, T.Munesue, D.N.Saito, T.Fujii, H.Yanaka, M.Ishitobi, K.Narita, T.Murata, M.Omori, N.Sadato, H.Okazawa, Y.Wada
     Nov.  2011
  • Radiolabeled Cu-ATSM as a novel indicator of over-reduced states in mitochondrial disorders: studies with mtDNA-less ρ0 cells and the cybrids carrying MELAS mtDNA mutation
    Y.Yoshii, M.Yoneda, M.Ikawa, T.Furukawa, Y.Kiyono, T.Mori, H.Yoshii, N.Oyama, H.Okazawa, T.Saga, Y.Fujibayashi
     Sep.  2011
  • Radiolabeled Cu-ATSM as a novel indicator of over-reduced states in mitochondrial disorders: studies with mtDNA-less rho0 cells and the cybrids carrying MELAS mtDNA mutation
    Y.Yoshii, M.Yoneda, M.Ikawa, T.Furukawa, Y.Kiyono, T.Mori, H.Yoshii, N.Oyama, H.Okazawa, T. Saga, Y.Fujibayashi
     Sep.  2011
  • Evaluation of radiobrominated (2S,aS)-2-(a-(2-bromophenoxy)benzyl)morpholine for imaging brain norepinephrine transporter
    Y.Kiyono, T.Takuda, K.Sano, R.Ikeda, T.Mori, M.Martinez, T.Asai, Y.Fujibayashi, H.Okazawa
     Aug.  2011
  • Automated synthesis of [18F]fluoroacetate using a compact FDG synthesizer
    T.Mori, R.Arai, B.Lambert, C.Gameiro-Paris, T.Kosuga, T.Asai, Y.Fujibayashi, H.Okazawa, Y.Kiyono
     Aug.  2011
  • Development of a flexible automatic synthesis module system for PET probe preparation
    Tetsuya Mori, Ryo Watanabe, Yasushi Kiyono, Yukie Yoshii, Hidehiko Okazawa, Yasuhisa Fujibayashi
    Society of Nuclear Medicine, the 58th Annual Meeting Jun.  2011
  • Additional diagnostic value of [F-18]-fluoroestradiol PET in patients with uterine smooth muscle tumors.
    Y.Yoshida, Y.Kiyono, T.Kurokawa, T.Tsujikawa, T.Mori, F.Kotsuji, H.Okazawa
     Jun.  2011
  • Evaluation of radiobromine-labeled 5-bromo-4'-thio-2'-deoxyuridine uptake in ACHN cells after treatment with 5-fluorouracil:Comparison with 3H-FLT uptake
    N.Takahara, Y.Kiyono, Y.Hasegawa, Y.Yoshii, Y.Fujibayashi, H.Okazawa, O.Yokoyama, N.Oyama
     Jun.  2011
  • Preparedness for Parenthood among Adolescent Males and Females - Continuous Learning Experience of Caring for Infants and the Evaluation of its Effects with the Scale of Readiness for Parenthood and fMRI ?
    佐々木 綾子, 小坂浩隆, 末原紀美代, 町浦美智子, 岡沢秀彦
     Jun.  2011
  • A novel application of radiolabeled Cu-ATSM as an indicator of intracellular over-reduced states in disorders with mitochondrial dysfunction: Studies with cybrids carrying mitochondrial DNA mutation from MELAS patients.
    Y.Yoshii, M.Yoneda, M.Ikawa, T.Furukawa, Y.Kiyono, T.Mori, H.Yoshii, N.Oyama, H.Okazawa, Y.Fujibayashi
     Jun.  2011
  • In ultra-short ECG gated acquisition of C-11 acetate PET reliable for simultaneous MBF, oxidative metabolism and myocardial function assessment?
    T.Kudo, K.Sarasawa, A.Nakano, T.Mori, Y.Kiyono, H.Okazawa
     Jun.  2011
  • In vivo evaluation of radiobromine-labeled 5-bromo-4-thio-2'-deoxyuridine as an imaging agent for tumor proliferation.
    Y.Kiyono, S.Sano, T.Mori, J.Toyohara, M.E.Martinez, T.Asai, H.Okazawa, Y.Fujibayashi
     Jun.  2011
  • The response inhibition load dependent activity: a functional MRI study
    Hisakazu T. Yanaka, Daisuke N. Saito, T.Kochiyama, Takeshi Fujii, H.Kosaka, T.Shimada, H.Okazawa
    Organization for Human Brain Mapping 2011 Annual Meeting Jun.  2011
  • Imaging of oxidative stress in patients with neurological disorders associated with mitochondrial dysfunction using 62Cu-ATSM PET
    M.Ikawa, H.Okazawa, K.Arakawa, T.Takeda, T. Kudo, H.Kimura, M.Kuriyama, Y.Fujibayashi, M.Yoneda
     Jun.  2011
  • Radiolabeled Cu-ATSM as a novel indicator of over-reduced states due to mitochondrial dysfunction: studies with mtDNA-less rho0 cells and the cybrids carrying MELAS mtDNA mutation
    M.Yoneda, Y.Yoshii, M.Ikawa, T.Takeda, T.Furukawa, Y.Kiyono, T.Mori, H.Yoshii, N.Oyama, H.Okazawa, Y.Fujibayashi
     Jun.  2011
  • Neural substrates of joint attention and inter-individual functional connectivity during mutual gaze in individuals with normal and autism spectrum disorders using dual functional MRI.
    Tanabe HC, Kosaka H, Saito DN, Munesue T, Okazawa H, Fujibayashi Y, Sadato N, Wada Y
     Jun.  2011
  • Clinical Usefulness of positron Emission Tomography/Computed Tomography And Magnetic Resonance Imagingg For Lung Cancer
    M.Morikawa, Y.Demura, Y.Umeda, S.Ameshima, T.Ishizaki, H.Okazawa
     May  2011
  • Predictive Value of Dual-time Point 18F-FDG PETimaging for Patients with Pulmonary sarcoidosis
    Y.Umeda, Y.Demura, M.Morikawa, S.Ameshima, H.Okazawa, F.Fujibayashi, T.Ishizaki
     May  2011
  • Evaluation of radiobrominated (2S,aS)-2-(a-(2-bromophenoxy)benzyl)morpholine as an imaging probe for brain norepinephrine transporter
    Y.Kiyono, T.Kakuda, R.Ikeda, K.Sano, T.Mori, M.Martinez, T.Asai, Y.Fujibayashi, H.Okazawa
     Jan.  2011
  • Predictive value of tracer accumulation to evaluate effects of cancer treatment studied using 62Cu-ATSM and 18F-FDG PET in head-and-neck cancers.
    H.Okazawa, A.Kositwattanarerk, Y.Kimura, Y.Kiyono, T.Mori, S.Fujieda
     Jan.  2011
  • Development of automatic synthesis of 16β-[18F]fluoro-5α-dihydrotestosterone using a plastic cassette-type FDG synthesizer
    T.Mori, C.S.Dence, M.J.Welch, Y.Fujibayashi, H.Okazawa, Y.Kiyono
     Jan.  2011
  • FDG Positron Emission Tomography Imaging of Drug-induced Pneumonitis (Scientific Presentation Award)
    M.Morikawa, Y.Demura, Y.Umeda, S.Ameshima, T.Ishizaki, H.Okazawa
     Jan.  2011
  • Evaluation of brain ischemic regions in patients with cerebrovascular disease using PET and hypoxic imaging tracer [Cu-62]-ATSM.
    H.Okazawa, M.Isozaki, T.Kudo, Y.Arai, Y.Kiyono
     Dec.  2010
  • Investigation on accumulation and therapeutic effect of64 Cu-ATSM in mouse colon carcinoma model: the relation to CD133+ highly tumorigenic cells
    Y.Yoshii, T.Furukawa, Y.Kiyono, R.Watanabe, T.Mori, H.Yoshii, H.Okazawa, M.J.Welch, Y.Fujibayashi
    2010 International Chemical Congress of Pacific Basin Societies Dec.  2010
  • Cu-ATSM is a novel indicator of intercellular over-reduced states in mitochondrial dysfunction: fundamental evaluation using mitochondrial DNA-less(ρ0)cells and cybrids carrying causal mitochondrial DNA mutation of MELAS syndrome
    Y.Kuroda, Y.Yoshii, M.Yoneda, M.Ikawa, Y.Kiyono, T.Mori, H.Yoshii, T.Furukawa, T.Asai, H.Okazawa, Y.Fujibayashi
    The 7th Conference of Asian Society for Mitochondrial Research and Medicine and The 10th Conference of Japanese Society of Mitochondrial Research and Medicine Dec.  2010
  • In vivo functional imaging of energy states and a therapeutic potential of L-arginine for patients with mitochondrial cardiomyopathy
    M.Ikawa, T.Kudo, K.Arakawa, Y.Kawai, T.Tsuchida, M.Kuriyama, H.Okazawa, M.Tanaka, M.Yoneda
     Dec.  2010
  • Whole-Body Diffusion-Weighted Magnetic Resonance Imaging Is a New Sensitive Non-Invasive Method for Staging and Monitoring Chemotherapy Response of Malignant Lymphoma including Indolent Lymphoma Compared with FDG-PET/CT
    S.Kishi, T.Tsuchida, T.Yamauchi, N.Hosono, S. kegaya, Y.Urasaki, H.Okazawa, H.Kimura, T.Ueda
    The 53rd American Society of Hematology Annual Meeting Dec.  2010
  • 3D tumor spheroids constructed with nano-sized pattern scaffoldings: a novel model for molecular imaging research
    Y.Yoshii, A. Waki, K.Yoshida, A.Kakezuka, M.Kobayashi, Y.Kuroda, Y.Kiyono, H.Yoshii, T.Furukawa, H.Okazawa, Y.Fujibayashi
    2010 World Molecular Imaging Congress Sep.  2010
  • Development of radiobromine-labeled thymidine analogue as a tumor proliferation imaging agent
    Y.Kiyono, K.Sano, T.Mori, M.E.Martinez, T.Asai, H.Okazawa, Y.Fujibayashi
     Sep.  2010
  • [62Cu]ATSM PET Demonstrates Increase of Striatal Oxidative Stress in Patients with Parkinson's Disease
    M.Ikawa, H.Okazawa, T.Kudo, M.Kuriyama, Y.Fujibayashi, M.Yoneda
     Sep.  2010
  • Effects of alendronate on bone metabolism in glucocorticoid-induced osteoporosis measured by 18F-fluoride positron emission tomography: A prospective study
    K.Uchida, H.Nakajima, T.Miyazaki, T.Yayama, H.Kawahara, T.Tsuchida, H.Okazawa, Y.Fujibayashi, H.Baba
     Jul.  2010
  • Evaluation of radiobromine-labeled 5-bromo-4’-thio-2’-deoxyuridine as a tumor proliferation imaging agent.
    Y.Kiyono, K.Sano, Y.Nakayama, T.Mori, J.Toyohara, M.E.Martinez Pozo, K.S.Mandap, T.Asai, H.Okazawa, Y.Fujibayashi
     Jun.  2010
  • Automated synthesis of 16β-[18F]fluoro-5α-dihydrotestosterone using a cassette-type FDG synthesizer
    T.Mori, Y.Kiyono, T.Asai, Y.Yoshii, H.Okazawa, C.S.Dence, M.J.Welch, Y.Fujibayashi
     Jun.  2010
  • Evaluation of 64Cu-ATSM for an internal radiotherapy agent: 64Cu-ATSM treatment reduces CD133+ highly tumorigenic cells and metastatic ability of tumors
    Yukie Yoshii, Takako Furukawa, Yasushi Kiyono, Ryo Watanabe, Tetsuya Mori, Hiroshi Yoshii, Hidehiko Okazawa, M. J. Welch, Yasuhisa Fujibayashi
    The Society of Nuclear Medicine (SNM) annual meeting 2010 Jun.  2010
  • Different distribution of 62Cu-ATSM and 18F-FDG in head-and-neck cancers
    H.Okazawa, M.Oh, T.Kudo, Y.Kiyono, M.Kobayashi, T.Mori, Y.Fujibayashi
     Jun.  2010
  • 11C-acetate PET imaging of recurrent prostate cancer after radical prostatectomy:detection of recurrent disease under PSA of 3.0 NG/ML
    N.Oyama, K.Tanase, H.Ito, N.Kusukawa, Y.Matsuta, Y.Aoki, Y.Miwa, H.Akino, T.Kudo, H.Okazawa, Y.Fujibayashi, O.Yokoyama
     Jun.  2010
  • Basic Research on the Development of Parenthood: Brain Activation Effects of Continuous Learning Experience of Caring for Infants in Adolescent Males and Females
    A.Sasaki, H.Kosaka, N.Sadato, H.Okazawa, M.Tanabe
     Jan.  2010
  • Neuroprotective effect of ketone bodies against hypoxia and ischemia in rat brain slices as measured by dynamic positron autoradiography
    T.Asai, N.Mimura, H.Okazawa, Y.Fujibayashi
    International Conference on Brain Function and Development Jan.  2010
  • Development of norepinephrine transporter imaging probe
    Y.Kiyono, N.Kanegawa, T.Sugita, K.S.Mandap, T.Mori, H.Saji, H.Okazawa, Y.Fujibayashi
    International Conference on Brain Function and Development Jan.  2010
  • Development of microwave-based autmated nucleophilic[18 F]fluorination system and its application for the production of[18F]flumazenil
    K.S.Mandap, T.Ido, Y.Kiyono, M.Kobayashi, T.G.Lohith, T.Mori, S.Kasamatsu, T.Kudo, H.Okazawa, Y.Fujibayashi
    Internatioal Conference on Brain Function and Development Jan.  2010
  • Automatic labeling method for injectabel 15O-oxygen using hemoglobin-containing liposome vesicles and its application for measurement of brain oxygen consumption by PET
    V.N.Tiwari, Y.Kiyono, M.Kobayashi, T.Mori, T.Kudo, H.Okazawa, Y.Fujibayashi
    International Conference on Brain Function and Development Jan.  2010
  • Measurement of cerebral blood flow and oxgen metabolism of rats using injectable O-15 oxygen and steady-state method combinig bolus and incresscent injection
    M.Kobayashi, V.N.Tiwari, Y.Kiyono, R.Maruyama, K.Kawai, Y.Fujibayashi, H.Okazawa
    International Conference on Brain Function and Development Jan.  2010
  • Functional imaging of oxidative stress in the nigrostriatal system of patients with Parkinson's disease by 62Cu-ATSM-PET
    M.Ikawa, H.Okazawa, T.Kudo, M.Kuriyama, Y.Fujibayashi, M.Yoneda
    International Conference on Brain Function and Development Jan.  2010
  • Therapeutic effect of CDP-choline for the corticobasal degeneration
    T.Hamano, K.Yamate, N.Shirafuji, T.Kishitani, T.Muramatsu, M.Ikawa, A.Matsunaga, A.Fujii, O.Yamamura, T.Tsuchida, T.Kudo, H.Okazawa, M.Kuriyama
    International Conference on Brain Function and Development Jan.  2010
  • Pathophysiologic evaluation of stroke-like episodes in MELAS patients by MRI and PET
    M.Yoneda, M.Ikawa, T.Tsujikawa, K.Arakawa, T.Kudo, Y.Fujibayashi, H.Kimura, H.Okazawa, M.Kuriyama
    International Conference on Brain Function and Development Jan.  2010
  • Cerebral blood flow and arterial transit time measurements in patients with chronic occlusive cerebrovascular disease using 3D spiral SE Arterial Spin Labeling on 3T-MR:Correlative study with O15labeled H2O PET examination
    H.Kimura, H.Okazawa, T.Matsuda, Y.Arai, D.C.Alsop
    International Conference on Brain Function and Development Jan.  2010
  • Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images
    T.Tsujikawa, M.Yoneda, H.Uematsu, M.Toyooka, M.Ikawa, T.Kudo, H.Okazawa, M.Kuriyama, H.Kimura
    International Conference on Brain Function and Development Jan.  2010
  • The 10 minutes exercise improves attentional ability in undergraduate students
    D.N.Saito, H.T.Yanaka, H.Kosaka, T.Shimada, H.Okazawa
    International Conference on Brain Function and Development Jan.  2010
  • Correlations between Smaller brain volume and Autism Spectrum Quotient or Intelligence Quotient in young male adults with pervasive developmental disorders
    H.Kosaka, M.Omori, T,Munesue, M.Ishitobi, Y.Matsumura, T.Takahashi, K.Narita, T.Murata, D.N.Saito, H.Uchiyama, T.Morita, T.Mizuno, M.Kikuchi, K.Mizukami, H.Okazawa, N.Sadato, Y.Wada
    International Conference on Brain Function and Development Jan.  2010
  • Development of radiobromine-labeled 5-bromo-4’-thio-2’-deoxyuridine as a tumor proliferation imaging agent.
    Y.Kiyono, K.Sano, Y.Nakayam, T.Mori, J.Toyohara, M.E.Martinez, K.S.Mandap, T.Asai, H.Okazawa, Y.Fujibayashi
     Jan.  2010
  • Feasibility of 62Cu-ATSM PET to delineate misery perfusion in patients with major cerebral arterial occlusive disease.
    H.Okazawa, M.Isozaki, Y.Arai, Y.Kiyono, T.Kudo, T.Mori, K.Kikuta
     Jan.  2010
  • 62Cu-ATSM PET demonstrates increase of striatal oxidative stress in patients with Parkinson’s disease
    M.Ikawa, H.Okazawa, T.Kudo, M.Kuriyama, Y.Fujibayashi, M.Yoneda
     Jan.  2010
  • 11C-acetate PET imaging of recurrent prostate cancer after radical prostatectomy:detection of recurrent disease under PSA of 3.0 NG/ML
    N.Oyama, N.Takahara, Y.Miwa, H.Akino, H.Okazawa, Y.Fujibayashi, O.Yokoyama
     Jan.  2010
  • Cingulate cortex dysfunction during self-face evaluation in pervasive developmental disorders.
    Morita T, Kosaka H, Saito DN, Ishitobi M, Munesue T, Itakura S, Omori M, Okazawa H, Wada Y, Sadato N
     Jan.  2010
  • Abnormal self-awareness in pervasive developmental disorders
    T.Morita, H.Kosaka, DN.Saito, M.Ishitobi, T.Munesue, S.Itakura, M.Omori, H.Okazawa, Y.Wada, N.Sadato
     Nov.  2009
  • 64Cu-ATSM imaging for cancer stem cell-rich regions: in vivo and in vitro characterization
    Y.Yoshii, Y.Kiyono, A.Waki, R.Watanabe, Y.Suzuki, T.Mori, H.Yoshii, T.Furukawa, T.Asai, T.Kudo, H.Okazawa, M.J.Welch, Y.Fujibayashi
     Sep.  2009
  • Automatic synthesis of 16beta-[18F]fluoro-5alpha-dihydrotestosterone using cassette-type [18F]FDG synthesizer
    Y.Kiyono, T.Mori, T.Asai, Y.Yoshii, H.Okazawa, Carmen S.Dence, Michael J.Welch, Y.Fujibayashi
     Sep.  2009
  • Does different distribution of 62Cu-ATSM and 18F-FDG reflect resistant tissue of cancers?
    M.Oh, T.Kudo, Y.Kiyono, Y.Fujibayashi, R.Maruyama, H.Okazawa
     Sep.  2009
  • Development of Parenthood for Adolescent Males and Females: Psychological, Physiological, and Brain Science Evaluation of First-hand Learning about Infants
    A.Sasaki, H.Kosaka, K.Suehara, M.Machiura, Y.Namizaki, K.Matu, M.Tanabe, N.Sadato, H.Okazawa
     Sep.  2009
  • Long-term prognosis of unilateral cerebrovascular disease with reduced arterial vasoreactivity.
    M.Isozaki, Y.Arai, T.Kudo, M.Kobayashi, Y.Handa, T.Kubota, H.Okazawa
     Jul.  2009
  • Benefit of pixel-by-pixel delay correction for measurement of hemodynamic parameters in patients with cerebrovascular disease using O-15 PET
    H.Okazawa, T.Kudo, M.Kobayashi, M.Isozaki, Y.Arai, T.Tsujikawa, Y.Fujibayashi, T.Kubota
     Jul.  2009
  • Developement of steady-state method combining bolus and increscent injection with a multi-programming syinge pump.
    M.Kobayashi, Y.Michibata, R.Maruyama, Y.Higaki, Y.Kiyono, T.Kudo, T.Tsujikawa, Y.Yoshii, A.Waki, K.Kawai, Y.Fujibayashi, H.Okazawa
     Jul.  2009
  • hANP treatment on acute myocardial infarction patients improves myocardial perfusion of risked myocardium: Measured with N-13 ammonia PET
    T.Kudo, H.Uzui, J-D.Lee, M.Kobayashi, T.Tsujikawa, Y.Fujibayashi, H.Okazawa
    2009 SNM Annual Meeting Jun.  2009
  • Functional estrogen receptor alpha imaging PET with 16alpha-[18F]fluoro-17beta-estradiol in endometrial carcinoma
    T.Tsujikawa, Y.Yoshida, T.Kudo, T.Kurokawa, Y.Kiyono, Y.Fujibayashi, H.Okazawa
     Jun.  2009
  • Intratumoral distribution pattern of FDG and Cu-62 ATSM in lung cancer patients using PET
    T.G.Lohith, T.Kudo, I.Miyamori, Y.Demura, S.Ameshima, T.Ishizaki, Y.Fujibayashi, H.Okazawa
     Jun.  2009
  • Measurement of cerebral oxygen metabolism of rats using injectable O-15 oxygen and steady-state method.
    M.Kobayashi, V.N.Tiwari, R.Maruyama, Y.Kiyono, T.Kudo, T.Tsujikawa, K.Kawai, Y.Fujibayashi, H.Okazawa
     Jun.  2009
  • Mechanism of renal FDG transcellular transport and cellular accumulation using LLC-PK1 cells
    M.Kobayashi, H.Araki, K.Nishi, N.Shikano, Y.Kiyono, R.Nashii, Y.Fujibayashi, H.Okazawa, K.Kawai
     Jun.  2009
  • Application of radioiodinated(2S,αS)-2-〔α-(2-iodophenoxy)benzy1〕morpholine to neuroendocrine tumor imaging
    Y.Kiyono, R.Nishii, J.Balatoni, Y.Yoshii, M.Kobayashi, Y.Magata, H.Okazawa, Y.Fujibayashi, J.Gelovani
    Society of Nuclear Medicine, the 56th Annual Meeting Jun.  2009
  • Functional estrogen receptor alpha imaging PET with 16alpha-[18F]fluoro-17beta-estradiol in endometrial carcinoma.
    辻川 哲也, 工藤 崇, 吉田 好雄, 清野 泰, 脇 厚生, 土田 龍郎, 藤林 康久, 岡沢 秀彦
     May  2009
  • 11C-acetate PET imaging for complicated renal cysts
    N.Oyama, T.Kurokawa, M.Taga, R.Yokogawa, H.Ito, Y.Aoki, Y.Miwa, H.Akino, Y.Fujibayashi, T.Kudo, H.Okazawa, O.Yokoyama
     Apr.  2009
  • Imaging of oxidative stress in the nigrostriatal system of patients with Parkinson’s disease using 62Cu-ATSM-PET
    M.Ikawa, H.Okazawa, T.Kudo, M.Kuriyama, Y.Fujibayashi, M.Yoneda
     Jan.  2009
  • Pathophysiologic evaluation of cerebral blood flow, energy status and oxidative stress during stroke-like episodes in MELAS patients by MRI and PET
    M.Yoneda, M.Ikawa, T.Tsujikawa, K.Arakawa, T.Kudo, Y.Fujibayashi, H.Kimura, H.Okazawa, M.Kuriyama
     Jan.  2009
  • Injectable O-15 system for oxygen metabolism studies using Hemoblobin vesicle (HbV):automatic labeling and applivation in rats using PET
    V.N.Tiwari, H.Okazawa, M.Kobayashi, T.Mori, S.Kasamatsu, Y.Fujibayashi
     Dec.  2008
  • Preparation and biological evalution of [18F]Flumazenil synthesized utilizing a mondified microwave reactor system
    K.S.Mandap, T.Ido, Y.Kiyono, M.Kobayashi, T.G.Lohith, T.Mori, S.Kasamatsu, H.Okazawa, Y.Fujibayashi
     Dec.  2008
  • Evaluation of radioiodinated (2S,AS)-2-[A-(2-iodophenoxy)benzyl]morpholine as an imaging probe for neuroendocrine tumor
    Y.Kiyono, R.Nishii, J.Balatoni, Y.Yoshii, M.Kobayashi, H.Okazawa, J.G.Gelovani, Y.Fujibayashi
    2008 Worl Molecular Imaging Congress Sep.  2008
  • Assessment of emission-based segmented attenuation correction method without transmission scan on small animal PET
    M.Kobayashi, Y.Higaki, T.Kudo, Y.Kiyono, T.Tsujikawa, Y.Yoshii, Y.Michibata, K.Sakai, M.Watanabe, K.Kawai, Y.Fujibayashi, H.Okazawa
    2008 Worl Molecular Imaging Congress Sep.  2008
  • 16alpha-[18F]fluoro-17beta-estradiol PET is useful for non-invasive estrogen receptor alpha imaging in endometrial carcinoma
    T.Tsujikawa, T.Kudo, Y.Yoshida, Y.Kiyono, M.Kobayashi, Y.Fujibayashi, H.Okazawa
    2008 Worl Molecular Imaging Congress Sep.  2008
  • Changes in glucose metabolic rate of rat spinal cord slices by neuronal perturbations measured by positron autoradiography
    T.Asai, X.Fan, K.Morioka, K.Uchida, K.Tanaka, H.Okazawa, Y.Fujibayashi
    The 31st Annual Meeting of the Japan Neuroscience Society Jul.  2008
  • Comparison of distribution of FDG and Cu-62 ATSM in head and neck cancer
    T.Kudo, T.Tsujikawa, M.Kobayashi, T.Tsuchida, M.Oh, S.Fujieda, T.Saga, H.Okazawa, Y.Fujibayashi
    The 55th annual meeting of society of nuclear medicine Jun.  2008
  • C-11 acetate washout in mitochondrial cardiomyopathy: Uncoupling between acetate washout and metabolism
    T.Kudo, T.Tsujikawa, M.Kobayashi, K.Arakawa, M.Ikawa, M.Yoneda, I.Miyamori, M.Kuriyama, Y.Fujibayashi, H.Okazawa
    The 55th Annual Meeting of Society of Nuclear Medicine Jun.  2008
  • Emission segmented attenuation correction method without transmission scan can accurately measure tracer concentration on small animal PET.
    M.Kobayashi, T.Kudo, Y.Kiyono, T.Tsujikawa, M.Watanabe, H.Okazawa, Y.Fujibayashi
    The 55th SNM Annual Meeting Jun.  2008
  • Clinical PET imaging using Cu-62-ATSM
    H.Okazawa
    The 55th SNM Annual Meeting Jun.  2008
  • Effect of transmission protocol on statistical analysis of brain 18F-FDG PET; Comparison between pre- and post-injection transmission scans.
    M.Kobayashi, T.Kudo, T.Tsujikawa, Y.Kiyono, Y.Fujibayashi, H.Okazawa
    Human Brain Mapping 2008 Jun.  2008
  • FES and FDG-PET imaging reflects clinical and histopathological findings in patients with endometrial carcinoma
    T.Tsujikawa, T.Kudo, Y.Yoshida, Y.Kiyono, M.Kobayashi, T.Tsuchida, Y.Fujibayashi, H.Okazawa
     Jun.  2008
  • Effect of intravenous adenosine-tri-phosphate (ATP) on cerebral blood flow by bolus 15O-labeled water PET study on human volunteers.
    R.Hussain, T.Tsuchida, T.Kudo, T.Tsujikawa, M.Kobayashi, Y.Fujibayashi, H.Okazawa
    The 55th SNM Annual Meeting Jun.  2008
  • Effect of L-systeine on bimding efficiency of hemoglobin-vesicles for development of an injectable O-15 labeling system.
    V.N.Tiwari, S.Kasamatsu, T.Mori, M.Kobayashi, H.Okazawa, Y.Fujibayashi
    The 55th SNM Annual Meeting Jun.  2008
  • Histological differentiation of lung cancer with 3-point imaging of FDG-PET
    T.Tsuchida, Y.Demura, H.Okazawa, T.Tsujikawa, T.Kudoh, H.Kimura
    The 55th annual meeting of society of nuclear medicine Jun.  2008
  • Evaluation of redox state and glycolytic metabolism in stroke-like episodes of MELAS patient on 62Cu-ATSM /18FDG-PET
    M.Yoneda, M.Ikawa, K.Arakawa, T.Kudo, H..Kimura, Y.Fujibayashi, M.Kuriyama, H.Okazawa
     Jun.  2008
  • C11-acetate washout in mitochondrial cardiomyoopathy: Uncoupling between acetate washout and metabolism
    T.Kudo, T.Tsujikawa, M.Kobayasi, K.Arakawa, M.Ikawa, M.Yoneda, I.Miyamori, M.Kuriyama, Y.Fujibayashi, H.Okazawa
     Jun.  2008
  • 11C-acetate PET imaging for cystic renal tumor
    N.Oyama, T.Kaneda, N.Kusukawa, M.Taga, K.Tsuchiyama, M.Maegawa, K.Tanase, H.Ito, Y.Aoki, Y.Miwa, H.Akino, Yokoyama.O, H.Okazawa, Y.Fujibayashi, Y.Yonekura
     Jun.  2008
  • 11C-acetate PET imaging in rental tumor
    N.Oyama, K.Tsuchiyama, N.Kusukawa, H.Ito, Y.Aoki, Y.Miwa, H.Akino, O.Yokoyama, H.Okazawa, Y.Fujibayashi, Y.Yonekura, Michael J Welch
     May  2008
  • Role of intravenous Adenosine-tri-phosphate(ATP) on human cerebral blood flow: assessed by bolus 15O-labeled water PET study
    R.Hussain, T.Tsuchida, T.Kudo, T.Tsujikawa, M.Kobayashi, Y.Fujibayashi, H.Okazawa
     May  2008
  • Accumulation of 62Cu- ATSM is different from that of 18F- FDG in head and neck cancer
    M.Oh, T.Kudo, T.Tsujikawa, M.Kobayashi, H.Okazawa, Y.Fujibayashi, S.Fujieda
     Apr.  2008
  • Delayed Enhancement of Myocardial FDG Uptake Indicates Metabolically Stunned but Viable Myocardium within Infarct-related Area in Patients with AMI
    中野 顯, 宇隨 弘泰, 見附 保彦, 下司 徹, 荒川 健一郎, 川人 充知, 工藤 崇, 岡沢 秀彦, 李 鍾大
    The 72nd Annual Scientific Meeting of the Japanese Circulation Society Mar.  2008
  • Utility of N-13 ammonia-PET for Predicting Short-term Left Ventricular Functional Recovery in Patients with AMI -Comparison with FDG-PET-
    阪田 純司, 下司 徹, 中野 顯, 宇隨 弘泰, 見附 保彦, 荒川 健一郎, 森川 玄洋, 嵯峨 亮, 皿澤 克彦, 兼八 正憲, 福岡 良友, 森下 哲司, 工藤 崇, 岡沢 秀彦, 李 鍾大
     Mar.  2008
  • Evaluation of myocardial damage and acute effects of L-Arginine using positron
    荒川 健一郎, 森川 玄洋, 嵯峨 亮, 兼八 正憲, 森下 哲司, 佐藤 岳彦, 皿澤 克彦, 阪田 純司, 下司 徹, 見附 保彦, 宇隨 弘泰, 中野 顯, 李 鍾大, 宮森 勇, 井川 正道, 米田 誠, 工藤 崇, 岡沢 秀彦, 河合 康幸
     Mar.  2008
  • Increase in cerebral blood flow and cerebral oxygen metabolism assessed by O-15 positron emission CT (O-15 PET) study and improved cognitive impairment after cilostazol treatment in patients with chronic cerebral infarction
    Y.Kawamura, M.Yoneda, M.Toyooka, A.Fujii, M.Kuriyama, H.Okazawa
     Feb.  2008
  • Clinical Application of Molecular Imaging: Feasibilty of Images for Receptor Function and Hypoxic Tissue.
    H.Okazawa
    The 12th Conference of Peace through Mind/Brain Science Feb.  2008
  • Effect of intravenous adenosine-tri-phosphate (ATP) on cerebral blood flow by bolus 15O-labeled water PET study
    R.Hussain, T.Tsuchida, T.Kudo, T.Tsujikawa, M.Kobayashi, Y.Fujibayashi, H.Okazawa
    The 13th National Conderence of Society of Nuclear Medicine, Bangladesh Feb.  2008
  • 18F-Fluorodeoxyglucose Positron Emission Tomography in Common Enhancing Malignant Brain Tumors
    N.Kosaka, H. Uematsu, H.Kimura, T.Tsuchida, H.Okazawa, H.Itoh
    Radiological society of North America, 93rd Scientific and Exihibition Nov.  2007
  • Evaluation of quantitative accuracy using the transmissionless-based emission segmented attenuation correction method in small animal PET
    M.Kobayashi, H.Okazawa, M.Oh, T.Tsujikawa, T.Mori, K.Sakai, M.Watanabe, Y.Kiyono, T.Kudo, K.Kawai, Y.Fujibayashi
     Sep.  2007
  • Potential of shorter examination time for diagnosis of misery perfusion using count-based OEF increase in O-15 gas PET.
    M.Kobayashi, H.Okazawa, T.Tsujikawa, T.Tsuchida, M.Isozaki, Y.Arai, K.Kawai, Y.Fujibayashi
    The 54th Annual Meeting of the Society of Nuclear Medicine Jun.  2007
  • Development of [18F]ethyl fluoroacetate as a tracer of oxidative metabolism in the brain
    T.Mori, L.Sun, M.Kobayashi, Y.Kiyono, T.Furukawa, H.Okazawa, Y.Fujibayashi
     Jun.  2007
  • 11C-Acetate PET imaging for renal tumor
    N.Oyama, T.Kaneda, M.Nakai, R.Shioyama, Y.Miwa, H.Akino, O.Yokoyama, H.Okazawa, Y.Fujibayashi, Y.Yonekura, M.J.Welch
     Jun.  2007
  • Importance of baseline CBF evaluation for detection of critical hemodynamic status in cerebrovascular disease: Comparison with acetazolamide test using PET.
    H.Okazawa, T.Tsujikawa, Y.Arai, M.Kobayashi, M.Isozaki, Y.Fujibayashi
    The 23rd International Symposium on Cerebral Blood Flow, Metabolism and Function (Brain 07) May  2007
  • Accurate delay correction for quantitative measurement of cerebral blood flow and arterial-to-capillary blood volume (V0).
    H.Okazawa, T.Tsujikawa, M.Kobayashi, M.Isozaki, Y.Arai
    The 8th International Conference on Quantification of Brain Function with PET May  2007
  • Possibility of scan time reduction for count-based OEF elevation in O-15 gas PET.
    M.Kobayashi, H.Okazawa, T.Tsujikawa, T.Tsuchida, M.Isozaki, Y.Arai, K.Kawai, Y.Fujibayashi
    The 8th International Conference on Quantification of Brain Function with PET May  2007
  • 11C-Acetate PET imaging for renal tumour
    大山 伸幸, 金田 大生, 中井 正治, 塩山 力也, 松田 陽介, 三輪 吉司, 横山 修, 岡沢 秀彦, 藤林 康久, 米倉 義晴
    28th Congress of the Society of International Urology Nov.  2006
  • Feasibility of F-18 FES-PET for gynecological tumors
    T.Tsujikawa, H.Okazawa, Y.Yoshida, T.Mori, T.Tsuchida, T.Kurokawa, M.Kobayashi, Y.Fujibayashi
     Sep.  2006
  • Evaluation of the count recovery coefficient of a whole-body PET/CT scanner in 3D mode image
    T. Tsujikawa, H.Okazawa, H. Otsuka, N. Morita, H. Nishitani
    Annual Congress of the European Association of Nuclear Medicine Sep.  2006
  • Evaluation of gynecological tumors and endometriosis using [F-18]-fluoroestradiol and PET
    H.Okazawa, Y.Yoshida, T.Mori, T.Tsuchida, T.Kurokawa, M.Kobayashi, T.Tsujikawa, Y.Yonekura, Y.Fujibayashi
    Annual Congress of the European Association of Nuclear Medicine Sep.  2006
  • How accurately can reductions in baseline CBF and vasoreactivity detect misery perfusion in cerebrovascular disease?
    H.Okazawa, T.Tsuchida, Y.Arai, M.Kobayashi, T.Mori, T.Tsujikawa, Y.Yonekura, Y.Fujibayashi
    Annual Congress of the European Association of Nuclear Medicine Sep.  2006
  • Diagnosis of misery perfusion using noninvasive 15O-gas PET
    M.Kobayashi, H.Okazawa, T.Tsuchida, K.Kawai, T.Mori, T.Tsujikawa, Y.Yonekura, Y.Fujibayashi
    Annual Congress of the European Association of Nuclear Medicine Sep.  2006
  • FDG-PET to exaluate response to intraarterial chemoradiotherapy for organ preservation in oral squamous cell carcinoma
    Y.Kitagawa, K.Sano, M.Nakamura, T.Ogasawara, H.Okazawa, Y.Fujibayashi, N.Sadato, Y.Yonekura
    Society of Nuclear Medicine, The 53rd Annual Meeting Jun.  2006
  • Evaluation of uterine endometrium related gynecological diseases using F-18 fluoroestradiol and PET
    H.Okazawa, Y.Yoshida, T.Mori, T.Tsuchida, T.Kurokawa, M.Kobayashi, Y.Fujibayashi, Y.Yonekura
     Jun.  2006
  • Evaluaion of Dual - Time Point FDG-PET Imaging for Staging in Patients with Lung Cancer
    D.Uesaka, Y.Demura, S.Ameshima, I.Miyamori, T.Ishizaki, M.Sasaki, T.Tsuchida, H.Itoh, H.Okazawa, Y.Yonekura
     May  2006
  • Acute effect of L-Arginine on tricarboxylic acid cycle metabolism evaluated by C11-acetate Kinetics on PET in mitochondorial cardiomyopathy
    K.Arakawa, Y.Kawai, N.Morikawa, T.Kumamoto, S.Itou, I.Miyamori, M.Yoneda, M.Igawa, M.Kuriyama, J-D.Lee, H.Okazawa, T.Tuchida, Ko Sahshi, Y.Koga
     Mar.  2006
  • Intensity of [F-18] fluorodeoxyglucose uptake in PET/CT correlates the clinical aggressiveness of malignant lymphoma
    T.Tsujikawa, H.Otsuka, H.Okazawa, Y.Fujibayashi, H.Nishitani
    The 9th Congress of World Federation of Nuclear Medicine & Biology Jan.  2006
  • Evaluation of gynecological tumors and endometriosis using F-18 fluoroestradiol and PET
    H.Okazawa, Y.Yoshida, T.Tsujikawa, T.Mori, T.Tsuchida, M.Kobayashi, Y.Fujibayashi
    The 9th Congress of World Federation of Nuclear Medicine & Biology Jan.  2006
  • Assessment of noninvasive examination method for diagnosis of misery perfusion in [O-15] oxygen-gas PET
    M.Kobayashi, H.Okazawa, T.Tsuchida, T.Tsujikawa, M.Isozaki, Y.Arai, K.Kawai, Y.Fujibayashi
    The 9th Congress of World Federation of Nuclear Medicine & Biology Jan.  2006
  • Evaluation of critical hemodynamic status induced by acetazolamide challenge in patients with cerebrovascular disease:assessment of regional perfusion pressure.
    H.Okazawa, T.Tsuchida, Y.Arai, T.Mori, M.Kobayashi, F.Tanaka, Y.Yonekura
    Brain '05 & BrainPET '05 Jun.  2005
  • Fluorine-18 fluoroestradional uptake in endometirum-influence of menstrual cycle and endogenous estrogen level.
    T.Tsuchida, H.Okazawa, Y.Fujibayashi, T.Mori, F.Tanaka, M.Kobayashi, K.Sugimoto, Y.Yonekura, H.Itoh
    Society of Nuclear Medicine 52nd Annual Meeting Jun.  2005
  • Effects of 5-HT1B/1D receptor agonist on cerebral blood flow and arterial blood volume:PET study with healthy volunteers.
    H.Okazawa, T.Tsuchida, M.Pagani, T.Mori, F.Tanaka, M.Kobayashi, Y.Yonekura
    Human Brain Mapping 2005 Jun.  2005
  • Relationship between misery perfusion and vasodilatory capacity assessed by acetazolamide test in patients with cerebrovascular disease:a PET syudy with O-15 gas and water
    H.Okazawa, T.Tsuchida, Y.Arai, T.Mori, M.Kobayashi, F.Tanaka, Y.Fujibayashi, Y.Yonekura
     Jun.  2005
  • Univariate analysis and PET
    H.Okazawa
    Annual Congress of the European Association of Nuclear Medicine, Symposium:The clinical impact statistical methods in the assessments of brain diseases with PET and SPECT Jan.  2005
  • Myocardial oxygen metabolism in diabetic patients was impaired even in non-infarct-related area after acute myocardial infarction
    Toyoda, K., Lee, J.D., Nakano, K., Uzui, H., Geshi, T., Amaya, N., Shirasaki, H., Mizuguchi, T., Ueda, T., Okazawa, H., Fujibayashi, Y., Yonekura, Y.
     Dec.  2004
  • Preserved microvascular function is related to late recovery of left ventricular wall motion in patients with acute myocardial infarction
    Geshi, T., Lee, J.D., Nakano, A., Uzui, H., Toyoda, K., Amaya, N., Shirasaki, H., Mizuguchi, T., Okazawa, H., Fujibayashi, Y., Yonekura, Y., Ueda, T.
     Dec.  2004
  • Differential diagnosis of pulmonary nodules with FDG-PET by means of SUV slope analysis
    Tsuchida, T., Okazawa, H., Tanaka, F., Yonekura, Y., Itoh, H.
     Dec.  2004
  • Relationship between impaired microvascular function and late recovery of left ventricular wall motion in patients with acute myocardial infarction
    T.Geshi, J-D.Lee, A.Nakano, H.Uzui, K.Toyoda, N.Amaya, H.Shirasaki, T.Mizuguchi, T.Ueda, H.Okazawa, Y.Fujibayashi, Y.Yonekura
     Dec.  2004
  • Evaluation of critical changes in cerebral perfusion pressure induced by vasodilatory stimulus in patients with cerebrovascular disease
    H.Okazawa, T.Tsuchida, T.Mori, Fujibayashi, Y., Y.Yonekura
     Dec.  2004
  • PET measurment of arterial part of cerebral perfusion pressure for evaluation of hemodynamic changes in cerebrovascular disease
    Okazawa, H., Tsuchida, T., Yamauchi, H., Yonekura, Y.
     Sep.  2004
  • Effects of metabolite correction for arterial input function and different calculation methods on quantitative receptor images in 11C-flumazenil PET study
    Okazawa, H., Yamauchi, H., Sugimoto, K., Kudo, T., Takahashi, M., Kishibe, Y., Yonekura, Y.
     Sep.  2004
  • Relationship between impaired microvascular function within non-infarct-related area and early left ventricular remodeling in patients with myocardial infarction
    T.Geshi, J-D.Lee, A.Nakano, H.Uzui, R.Nakaya, K.Toyoda, N.Amaya, H.Shirasaki, T.Mizuguchi, T.Ueda, H.Okazawa, Y.Fujibayashi, Y.Yonekura
     Jul.  2004
  • Relationship between intetr-branch (artery-to-artery) steal and transient ischemic dilatation: Evaluation with ECG gated N-13 ammonia PET
    T.Kudo, H.Yamauchi, T.Hata, H.Tamai, H.Okazawa, M.Takahashi, Y.Kishibe, K.Sugimoto
    The Society of Nuclear Medicine 51st Annual Meeting Jun.  2004
  • Relationship between inter-branch (artery-to-artery) steal and transient ischemic dilatation- evaluation with ECG gated N-13 ammonia PET
    Kudo, T., Yamauchi, H., Hata, T., Tamai, H., Okazawa, H., Takahashi, M., Kishibe, Y., Sugimoto, K.
     Jun.  2004
  • Imaging of glioma with carbon-11 acetate-PET-comparison with F-18 FDG-PET
    Tsuchida, T., Nishizawa, S., Okazawa, H., Yonekura, Y., Itoh, H.
     Jun.  2004
  • Effects of acetazolamide on cerebral perfusion pressure in patients with cerebrovascular disease
    H.Okazawa, H.Yamauchi, T.Tsuchida, M.Takahashi, Y.Fujibayashi, Yonekura, Y.
     Jun.  2004
  • Relationship between impaired microvascular function within non-infarct-related area and early left ventricular remodeling in patients with myocardial infarction
    Geshi, T., Lee, J.D., Nakano, A., Uzui, H., Toyoda, K., Amaya, N., Shirasaki, H., Mizuguchi, T., Okazawa, H., Fujibayashi, Y., Yonekura, Y., Ueda T.
     Mar.  2004
  • Preserved microvascular function is related to late recovery of left ventricular wall motion in patients with acute myocardial infarction
    Geshi, T., Lee, J.D., Nakano, A., Uzui, H., Toyoda, K., Amaya, N., Shirasaki, H., Mizuguchi, T., Okazawa, H., Fujibayashi, Y., Yonekura, Y., Ueda, T.
     Jan.  2004
  • Measurement of arterial part of vascular volume (V0) for evaluation of hemodynamic changes in cerebrovascular disease
    Okazawa, H., Yamauchi, H., Yonekura, Y.
     Jan.  2004
  • Effects of metabolite correction for arterial input function on quantitative receptor images in 11C-flumazenil PET study
    Okazawa, H., Yamauchi, H., Sugimoto, K., Magata, Y., Kudo, T., Yonekura, Y.
     Aug.  2003
  • Differences in acetazolamide induced vasodialatation and cerebral blood flow increase between healthy volunteers and patients with cerebrovascular disease
    Okazawa, H., Yamauchi, H., Sugimoto, K., Takahashi, M., Yonekura, Y.
     Aug.  2003
  • Correction factors for quantitative measurement of CBF by dynamic susceptibility constrast MRI
    Shiino, A., Higuchi, K., Morita, Y., Okazawa, H., Yamauchi, H., Matsuda, M.
     Jun.  2003
  • The effect of acetazolamide on the changes of cerebral blood flow and oxygen metabolism during visual stimulation
    Yamauchi, H., Okazawa, H., Kishibe, Y., Sugimoto, K., Takahashi, M.
     Jun.  2003
  • A simplified autoradiographic method with α-methyl-tryptophan to measure serotonin synthesis rate in the rat brain
    Nishizawa, S., Okazawa, H., Yonekura, Y., Diksic, M.
     Jun.  2003
  • Changes in cerebral blood flow and blood volume induced by acetazolamide challenge studied in patients with moyamoya disease -A PET study using the H215O bolus method
    Okazawa, H., Yamauchi, H., Takahashi, M., Kishibe, Y., Matsugi, H., Sugimoto, K.
     Jun.  2003
  • Relationship of vasodilatation and cerebral blood flow increase induced by acetazolamide studied in patients with cerebrovascular disease
    Okazawa, H., Yamauchi, H., Takahashi, M., Kishibe, Y., Sugimoto, K.
     Jun.  2003
  • Assessment of non-protein thiols concentration and 99mTc-meso-HMPAO uptake in mouse brain at normoxic, hyperoxic and hypoxic ambient conditions
    M.Pagani, T.Sasaki, T.Furukawa, F.Micucci, H.Okazawa, K.Kawai, M.Yoshimoto, Y.Yonekura, Fujibayashi, Y.
     Jun.  2003
  • Changes in 99mTc-meso-HMPAO uptake and in glutathione and non-protein thiols concentrations in mouse brain following exposure to normobaric hyperoxia
    M.Pagani, T.Sasaki, T.Furukawa, F.Micucci, H.Okazawa, K.Kawai, M.Yoshimoto, Y.Yonekura, Y.Fujibayashi
     Jun.  2003
  • Daily anaerobic threshold level walking improves regional myocardial circulation at rest and dipyridamole hyperlemia in patients with old myocardial infarction
    Hata, T., Okazawa, H., Takeda, S., Tsuji, T., Fujita, S., Okada, M., Nakamura, T., Kosuga, K., Hsu, Y-S., Tamai, H., Motohara, S., Uehata, H.
     Mar.  2003
  • Rates of Brain 5-HT Synthesis in Patients with Obsessive-Compulsive
    Leyton M, Diksic M, Barsoum A, Okazawa H, Nakai A, Kumakura Y, Sookman D, Mzengeza S, Blier P, Benkelfat C
    The 38th the American College of Neuropsychopharmacology (ACNP) Annual Meeting. Dec.  1999
  • Plasma-to-Brain Clearance of 11C-alpha-Methyl-Tryptophan in Patients with
    Benkelfat C, Leyton M, Barsoum A, Sookman D, Nakai A, Okazawa H, Pinard G, Mzengeza S, Blier P, Diksic M
    The 38th the American College of Neuropsychopharmacology (ACNP) Annual Meeting. Dec.  1999
  • Uptake of [11C] alpha Methyl-L-Tryptophan in Patients with Intractable
    Fedi M, Reutens DC, Okazawa H, Andermann F, Dubeau F, Boling W, White C, A.Nakai, Gross DW, Andermann E, Diksic M
    The 51st Annual Meeting of American Academy of Neurology. Apr.  1999
  • 分子イメージングによるMELAS脳卒中様発作の病態解明
    井川 正道, 岡沢 秀彦, 辻川 哲也, 清野 智恵子, 前田 浩幸, 川谷 正男, 畑 郁江, 木村 浩彦, 和田 有司, 米田 誠
    第36回北陸臨床遺伝研究会 Feb.  2016
  • New Frontiers of Fusion Images in Neuroimaging
    Okazawa H
     Apr.  2018
  • Count-based method for specific binding ratio calculation in [I-123]FP-CIT SPECT analysis
    Rahman M, Islam M, Tsujikawa T, Sugimoto K, Okazawa H
    The 12th World Congress of the World Federation of Nuclear Medicine and Biology (WFNMB 2018) Apr.  2018 World Federation of Nuclear Medicine and Biology
  • A new method for [123I]FP-CIT specific binding ratio estimation in evaluation of striatal function
    Rahman M, Islam M, Tsujikawa T, Kiyono Y, Okazawa H
    The 65th Annual Meeting of The Society of Nuclear Medicine Jun.  2018 Society of Nuclear Medicine
  • Functional imaging using PET
    Hidehiko Okazawa
     Sep.  2018
  • Role of PET/MRI in oral cavity and oropharyngeal cancer based on the 8th edition of the AJCC cancer staging system
    Tsujikawa T, Narita N, Kannno M, Takabayashi T, Fujieda S, Okazawa H
    The 12th World Congress of the World Federation of Nuclear Medicine and Biology (WFNMB 2018) Apr.  2018 World Federation of Nuclear Medicine and Biology
  • Selected PET radiomic features remain the same - Clinical validation with PET/CT & PET/MRI -
    Tsujikawa T, Tsuyoshi H, Kannno M, Yamada S, Kobayashi M, Narita N, Kimura H, Fujieda S, Yoshida Y, Okazawa H
    The 77th Annual Meeting of the Japan Radiological Society Apr.  2018
  • Integrated FDG-PET/MRI enhances the diagnostic ability for distinguishing between type I and II endometrial cancers
    Tsujikawa T, Tsuyoshi H, Yamada S, Shinagawa A, Chino Y, Kurokawa T, Yoshida Y, Okazawa H
    The 65th Annual Meeting of The Society of Nuclear Medicine Jun.  2018 Society of Nuclear Medicine
  • Assessment of bone marrow proliferation in bone marrow failure syndrome by FLT-PET/MRI
     Nov.  2018
  • Development of nanoparticles for internal radiation therapy
     Nov.  2018
  • Examination on simple preparation method of Cu-64 labeled nanoparticle
     May  2018
  • Development of thermo-sensitive polymer micelle for direct injection at the targeted tumor region
    Makino A, manabe T, Asai T, Okazawa H, Kiyono Y
    256th ACS National Meeting Aug.  2018 American Chemical Society
  • Predictive value of 18F-FDG and 18F-FLT uptake in colorectal cancer treated with charged particle irradiation under hypoxic condition
    Kiyono Y, Makino A,Kume K,Mori T,Asai T, Okazawa H
    The 65th Annual Meeting of The Society of Nuclear Medicine Jun.  2018
  • Changes in the accumulation of 18F-FDG and 18F-FLT in colorectal cancer cells treated with charged particle irradiation under hypoxic condition
    Kiyono Y, Kume K, Makino A, Mori T, Asai T, Okazawa H
    The 12th World Congress of the World Federation of Nuclear Medicine and Biology (WFNMB 2018) Apr.  2018
  • Validation study of F-18 labeled sodium fluoride (NaF) for a GMP production
     Nov.  2018
  • Development of human right inferior parietal lobule associated with self-body recognition
     Mar.  2018

Awards & Honors

  •  Societu of Nuclear Medicine 2011 SNM Annual Meeting Oncology: Clinical Diagnosis, Top 10 Poster Award Finalists: First PlaceJun. 2011
  •  The Japanese Society of Nuclear Medicine The 40th Award of the Japanese Borard of Nuclear MedicineNov. 2002