Matsuzaki Hideo

FacultyResearch Center for Child Mental Development
Teacher OrganizationResearch Center for Child Mental Development
Education and
 Research Organization
Research Center for Child Mental Development
PositionProfessor
Last Updated: 19/11/29 14:59

Researcher Profile & Settings

Name

    Matsuzaki Hideo

Affiliation

  •  Research Center for Child Mental Development Professor

Academic & Professional Experience

  • Jan. 2002Mar. 2005Department of Psychiatry, Yale University School of Medicine Postdoctoral Associates

Association Memberships

    International Society for Autism Research member,Society for Neuroscience member,

Research Activities

Published Papers

  • CD38 is required for dendritic organisation in visual cortex and hippocampus.
    TP.Nelissen, RA.Bamford, S.Tochitani, K.Akkus, A.Kudzinskas, K.Yokoi, H.Okamoto, Y.Yamamoto, JPH. Burbach, H.Matsuzaki, A.Oguro-Ando.
    Neuroscience 372 114-125 Feb.  2018 Refereed
  • Autism-like behaviors and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice.
    N.Morimura, H.Yasuda, K.Yamaguchi, K.Katayama, M.Hatayama, N.Tomioka, M.Odagawa, A.Kamiya, Y.Iwayama, M.Maekawa, K.Nakamura, H.Matsuzaki, M.Tsujii, K.Yamada, T.Yoshikawa, J.Aruga.
    Nat Commun. 8(15800) Jun.  2017 Refereed
  • ARPP-16 is a striatal-enriched inhibitor of protein phosphatase 2A regulated by microtubule-associated serine/threonine kinase 3.
    E.Andrade, V.Musante, A.Horiuchi, H.Matsuzaki, A.Brady, T.Wu, P.Greengard, J.Taylor, A.Nairn.
    J Neurosci. 37(10) 2709-2722 Mar.  2017 Refereed
  • Microglia-derived neuregulin expression in psychiatric disorders.
    D.Ikawa, M.Makinodan, K.Iwata, M.Ohgidani, T.Kato, Y.Yamashita, K.Yamamuro, S.Kimoto, M.Toritsuka, T.Yamauchi, S.Fukami, H.Yoshino, K.Okumura, T.Tanaka, A.Wanaka, Y.Owada, M.Tsujii, T.Sugiyama, KJ.Tsuchiya, N.Mori, R.Hashimoto, H.Matsuzaki, S.Kanba, T.Kishimoto.
    Brain Behav. Immun. 61 375-385 Mar.  2017 Refereed
  • Tumor necrosis factor-alpha expression in peripheral blood mononuclear cells correlates with early childhood social interaction in autism spectrum disorder.
    M.Makinodan, K.Iwata, D.Ikawa, Y.Yamashita, K.Yamamuro, M.Toritsuka, S.Kimoto, K.Okumura, T.Yamauchi, H.Yoshino, M.Tsujii, T.Sugiyam, KJ.Tsuchiya, N.Mori, H.Matsuzaki, T.Kishimoto.
    Neurochem. Int. 104 1-5 Mar.  2017 Refereed
    :Autism spectrum disorder is a neurodevelopmental disorder characterized by impaired social interaction, poor communication skills, and repetitive/restrictive behaviors. Elevated blood levels of pro-inflammatory cytokines have been reported in subjects with autism spectrum disorder. On the other hand, early childhood adverse experience also increases blood levels of these cytokines. Since social experience of children with autism spectrum disorder is generally unlike to typically developing children, we hypothesized that social interaction during childhood contribute to pro-inflammatory cytokine expression in subjects with autism spectrum disorder. We compared revised Autism Diagnostic Interview scores and expression levels of pro-inflammatory cytokines in peripheral blood mononuclear cells of subjects with autism spectrum disorder (n = 30). The score of domain A on the revised Autism Diagnostic Interview, indicating social interaction impairment in early childhood, was negatively correlated with tumor necrosis factor-α mRNA expression level in peripheral blood mononuclear cells but not interleukin-1β or -6. Consistently, tumor necrosis factor-α mRNA expression was markedly low in subjects with autism spectrum disorder compared to typically developing children who presumably experienced the regular levels of social interaction. These findings suggest that the low blood levels of tumor necrosis factor-α mRNA in subjects with autism spectrum disorder might be due to impaired social interaction in early childhood.
  • Mismatch in cerebral blood flow and glucose metabolism after the forced swim stress in rats.
    Y.Kameno, K.Suzuki, S.Takagai, K.Iwata, H.Matsuzaki, K.Takahashi, T.Wakuda, Y.Iwata, Y.Magata, N.Mori
    Acta Neuropsychiatr. 28(6) 352-356 Dec.  2016 Refereed
  • Fetal Environment and Glycosylation Status in Neonatal Cord Blood: A Comprehensive Mass Spectrometry-based Glycosylation Analysis.
    R.Sato, KJ.Tsuchiya, H.Matsuzaki, N.Takei, H.Itoh, N.Kanayama, T.Suda, H.Watanabe, T.Ohashi, M.Tanaka, S.Nishimura, M.Maekawa; HBC study group.
    Medicine (Baltimore) 95(14) Apr.  2016 Refereed
    :Fetal environment is known to be a major predictive factor of type 2 diabetes and cardiovascular disease. However, associations of fetal environment and cord blood glycoforms are uncertain. In this study, we aimed to determine whether glycosylation status in neonatal cord blood is associated with perinatal outcomes reflecting a poor fetal environment.Thirty-six low birth weight (LBW) infants and 120 normal birth weight infants were recruited from a longitudinal birth cohort. We conducted a comprehensive cord blood N-glycan analysis using matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry. Associations of N-glycans with perinatal outcomes, including LBW, small for gestational age, and levels of cord blood leptin and adiponectin, were evaluated using logistic or multiple regression. We also prospectively explored correlations between N-glycans and 6 or 18-month rapid weight gain (>0.67 SD score).A total of 35 N-glycans were detected (m/z value 1362.481-3865.407). Of these, abundance levels of G3414 (m/z value 3414.238) were inversely correlated with LBW and small for gestational age. Abundance levels of G1915 (m/z value 1914.698), G2744 (m/z value 2743.994), G3049 (m/z value 3049.105), and G3719 (m/z value 3719.349) were inversely related to LBW. The total N-glycan abundance levels were strongly positively correlated with levels of leptin and adiponectin in cord blood. In a prospective exploratory analysis, the 5 LBW-related N-glycans (G1915, G2744, G3049, G3414, and G3719) were all inversely associated with 6 or 18-month rapid weight gain. These N-glycans are structurally categorized into 2 different categories: fucosylated bi or tri-antennary N-glycans; and tri or tetra-antennary N-glycans without fucosylation.In conclusion, mass spectrometry-based cord blood glycosylation analysis shows that 5 types of N-glycans are potential predictors of a poor fetal environment.
  • Erratum: Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism.
    M.Maekawa, Y.Iwayama, T.Ohnishi, M.Toyoshima, C.Shimamoto, Y.Hisano, T.Toyota, S.Balan, H.Matsuzaki, Y.Iwata, S.Takagai, K.Yamada, M.Ota, S.Fukuchi, Y.Okada, W.Akamatsu, M.Tsujii, N.Kojima, Y.Owada, H.Okano, N.Mori, T.Yoshikawa
    Sci Rep. 6 20268 Jan.  2016 Refereed
  • Administration of non-absorbable antibiotics to pregnant mice to perturb the maternal gut microbiota is associated with alterations in offspring behavior.
    S.Tochitani, T.Ikeno, T.Ito, A.Sakurai, T.Yamauchi, H.Matsuzaki
    PLoS One. 11(1) e0138293 Jan.  2016 Refereed
  • Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism
    M.Maekawa, Y.Iwayama, T.Ohnishi, M.Toyoshima, C.Shimamoto, Y.Hisano, T.Toyota, S.Balan, H.Matsuzaki, Y.Iwata, S.Takagai, K.Yamada, M. Ota, S.Fukuchi, Y.Okada, W.Akamatsu, M.Tsujii, N.Kojima, Y.Owada, H.Okano, N.Mori, T.Yoshikawa
    Sci Rep. 5 16239 Nov.  2015 Refereed
  • Effectiveness of oral tipepidine administration for children with attention deficit/hyperactivity disorder: A 4-week, open-label clinical study.
    A.Tomoda, S.Takiguchi, TX.Fujisawa, C.Yatsuga, H.Kumazaki, T.Fujioka, H.Suzuki, H.Matsuzaki, H.Kosaka, and S.Tanaka
    Psychiatry Clin Neurosci. 69(10) 658-659 Sep.  2015 Refereed
  • Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses
    M.Maekawa, K.Yamada, M.Toyoshima, T.Ohnishi, Y.Iwayama, C.Shimamoto, T.Toyota, Y.Nozaki, S.Balan, H.Matsuzaki, Y.Iwata, K.Suzuki, M.Miyashita, M.Kikuchi, M.Kato, Y.Okada, W.Akamatsu, N.Mori, Y.Owada, M.Itokawa, H.Okano, T.Yoshikawa
    Biol Psychiatry. 78(2) 116-125 Jul.  2015 Refereed
  • Perinatal asphyxia alters Neuregulin-1 and COMT gene expression in the medial prefrontal cortex in rats
    T.Wakuda, K. Iwata, Y.Iwata, A.Anitha, T.Takahashi, H.Matsuzaki, K.Suzuki, N.Mori
    Prog. Neuropsychopharmacol. Biol. Psychiatry. 56 149-154 Sep.  2014 Refereed
  • Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses
    M.Maekawa, K.Yamada, M.Toyoshima, T.Ohnishi, Y.Iwayama, C.Shimamoto, T.Toyota, Y.Nozaki, S.Balan, H.Matsuzaki, Y.Iwata, K.Suzuki, M.Miyashita, M.Kikuchi, M.Kato, Y.Okada, W.Akamatsu, N.Mori, Y.Owada, M.Itokawa, H.Okano, T.Yosikawa
    Biol Psychiatry pii: S0006-3223(14) 00570-8 Sep.  2014 Refereed
  • Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades
    K.Terada, N.Izumo, B.Suzuki, Y.Karube, T.Morikawa, Y.Ishibashi, T.Kameyama, K.Chiba, N.Sasaki, K. Iwata, H.Matsuzaki, T.Manabe
    Neurochem. Int. in press Feb.  2014 Refereed
  • The human oligodendrocyte proteome
    K.Iwata, CC.Cafe-Mendes, A.Schmitt, T.Manabe, H.Matsuzaki, P.Falkai, CW.Turck, D.Martins-de-Souza
    Proteomics. 13(23-24) 3548-3553 Dec.  2013 Refereed
  • Serum levels of soluble platelet endothelial cell adhesion molecule-1 and vascular cell adhesion molecule-1 are decreased in subjects with autism spectrum disorder
    Y.Kameno, K. Iwata, H.Matsuzaki, T.Miyachi, KJ.Tsuchiya, K.Matsumoto, Y.Iwata, K.Suzuki, K.Nakamura, M.Maekawa, M.Tsujii, T.Sugiyama, N.Mori
    Mol Autism 4(1) 19 Jun.  2013 Refereed
  • 60. Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism
    C.Shimmura, K.Suzuki, Y.Iwata, KJ.Tsuchiya, K.Ohno, H.Matsuzaki, K. Iwata, Y.Kameno, T.Takahashi, T.Wakuda, K.Nakamura, K.Hashimoto, N.Mori
    Mol Autism 4(1) 6 Mar.  2013 Refereed
  • Seasonal Variations of Neuromotor Development By 14 Months of Age: Hamamatsu Birth Cohort for Mothers and Children (HBC Study)
    KJ,Tsuchiya, H.Tsutsumi, K.Masumoto, N.Takei, M.Nakamura, M.Honda, I.Thanseem, A.Anitha, K.Suzuki, H.Matsuzaki, Y.Iwata, K.Nakamura, N,Mori
    PLoS One. 7(12) e52057 Dec.  2012 Refereed
  • Brain Region-Specific Altered Expression, and Association of Mitochondria-Related Genes in Autism
    A.Anitha, K.Nakamura, I.Thanseem, K.Yamada, Y.Iwayama, T.Toyota, H.Matsuzaki, T.Miyachi, S.Yamada, M.Tsujii, KJ.Tsuchiya, K.Masumoto, Y.Iwata, K.Suzuki, H.Ichikawa, T.Sugiyama, T.Yoshikawa, N,Mori
    Mol Autism. 3(1) 12 Nov.  2012 Refereed
  • Downregulation of the Expression of Mitochondrial Electron Transport Complex Genes in Autism Brains
    A.Anitha, K.Nakamura, I.Thanseem, H.Matsuzaki, T.Miyachi, M.Tsujii, Y.Iwata, K.Suzuki, T.Sugiyama, N.Mori
    Brain Pathol. 23(3) 294-302 Nov.  2012 Refereed
  • Diminished Medial Prefrontal Activity Behind Autistic Social Judgments of Incongruent Information
    T.Watanabe, N.Yahata, O.Abe, H.Kuwabata, H.Inoue, Y.Takano, N.Iwashiro, T.Natsubori, Y.Aoki, H.Takao, H.Sasaki, W.Gonoi, M.Murakami, M.Katsura, A.Kunimatsu, H.Matsuzaki, Y.Kawakubo, KJ.Tsuchiya, N.Kato, Y.Kano, Y.Miyashita, K.Kasai, H.Yamasue
    PLoS One. 7(6) e39561 Jun.  2012 Refereed
  • Elevated Transcription Factor Sp1 in Autistic Brains Alters the Expression of Autism Candidate Genes
    I.Thanseem, A.Anitha, K.Nakamura, S.Suda, K.Iwata, H.Matsuzaki, M.Ohtsubo, T.Ueki, T. Katayama, Y.Iwata, K.Suzuki, S.Minoshima, N.Mori
    Biol Psychiatry. 71(5) 410-418 Mar.  2012 Refereed
  • Triggers for Autism: genetic and environmental factors
    H.Matsuzaki, K.Iwata, T.Manabe, N.Mori
    Journal of Central Nervous System Disease. 4 42014 Feb.  2012 Refereed
  • Vldlr overexpression causes hyperactivity in rats
    K.Iwata, N.Izumo, H.Matsuzaki, T.Manabe, Y.Ishibashi, Y.Ichitani, K.Yamada, I.Thanseem, A.Anitha, MM.Vasu, C.Shimmura, T.Wakuda, Y.Kameno, T.Takahashi, Y.Iwata, K.Suzuki, K.Nakamura, N.Mori
    Mol Autism. 3(1) 11 Jan.  2012 Refereed
  • Absence of age-related prefrontal NAA change in adults with autism spectrum disorders
    Y.Aoki, O.Abe, N.Yahata, H.Kuwabara, T.Matsubori, N.Iwashiro, Y.Takano, H.Inoue, Y.Kawakubo, W.Gonoi, H.Sasaki, M.Murakami, M.Katsura, Y.Nippashi, H.Takao, A.Kunimatsu, H.Matsuzaki, KJ.Tsuchiya, N.Kato, K.Kasai, H.Yamasue
    Transl Psychiatry. 2 e178 Jan.  2012 Refereed
  • Psychosocial risk factors for postpartum depression and their relation to timing of onset: the Hamamatsu Birth Cohort (HBC) Study
    T.Mori, KJ.Tsuchiya, K.Matsumoto, K.Suzuki, N.Mori, N.Takei, H.Matsuzaki(The HBC Study Team)
    J Affect Disord. 135(42007) 341-346 Dec.  2011 Refereed
  • Altering the expression balance of hnRNP C1 and C2 changes the expression of myelination-related genes
    K.Iwata, H.Matsuzaki, T.Manabe, T.Mori
    Psychiatry Res. 190(42038) 364-366 Dec.  2011 Refereed
  • Association of Transcription Factor Gene LMX1B with Autism
    I.Thanseem, K.Nakamura, A.Anitha, S.Suda, K.Yamada, Y.Iwayama, T.Toyota, M.Tsujii, Y.Iwata, K.Suzuki, H.Matsuzaki, K.Iwata, T.Sugiyama, T.Yoshikawa, N.Mori
    PLoS One. 6(8) e23738 Jun.  2011 Refereed
  • Plasma cytokine profiles in subjects with high-functioning autism spectrum disorders
    K.Suzuki, H.Matsuzaki, K.Iwata, Y.Kameno, C.Shinmura, S.Kawai, Y.Yoshihara, T.Wakuda, K.Takebayashi, S.Takagai, K.Matsumoto, KJ.Tsuchiya, Y.Iwata, K.Nakamura, M.Tsujii, S.Sugiyama, N.Mori
    PLoS One. 6(5) e20470 Apr.  2011 Refereed
  • Replication study of Japanese cohorts supports the role of STX1A in autism susceptibility
    K.Nakamura, Y.Iwata, A.Anitha, T.Miyachi, T.Toyota, S.Yamada, M.Tsujii, KJ.Tsuchiya, Y.Iwayama, K.Yamada, E.Hattori, H.Matsuzaki, K.Matsumoto, K.Suzuki, S.Suda, K.Takebayashi, N.Takei, H.Ichikawa, T.Sugiyama, T.Yoshikawa, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 35(2) 454-458 Mar.  2011 Refereed
  • Investigation of the serum levels of anterior pituitary hormones in male children with autism
    K.Iwata, H.Matsuzaki, T.Miyachi, C.Shimmura, S.Suda, KJ.Tsuchiya, K.Matsumoto, K.Suzuki, Y.Iwata, K.Nakamura, M.Tsujii, T.Sugiyama, K.Sato, N,Mori
    Mol Autism. 2(1) 16 Jan.  2011 Refereed
  • Alteration of Plasma Glutamate and Glutamine Levels in Children with High-Functioning Autism
    C.Shimmura, S.Suda, KJ.Tsuchiya, K.Hashimoto, K.Ohno, H.Matsuzaki, K.Iwata, K.Matsumoto, T.Wakuda, Y.Kameno, K.Suzuki, M.Tsujii, K.Nakamura, N.Takei, N.Mori
    PLoS One. 6(10) e25340 Jan.  2011 Refereed
  • Age-specific 3-month cumulative incidence of postpartum depression: The Hamamatsu Birth Cohort (HBC) Study
    K.Matsumoto, KJ.Tsuchiya, H.Itoh, N.Kanayama, S.Suda, H.Matsuzaki, K.Iwata, K.Suzuki, K.Nakamura, N.Mori, N.Takei
    J Affect Disord. 133(3) 607-610 Jan.  2011 Refereed
  • Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism
    S.Suda, K.Iwata, C.Shimmura, Y.Kameno, A.Anitha, I.Thanseem, K.Nakamura, H.Matsuzaki, KJ.Tsuchiya, G.Sugihara, Y.Iwata, K.Suzuki, K.Koizumi, H.Higashida, N.Takei, N.Mori
    Mol Autism. 2(1) 14 2011 Refereed
  • Animal models of autism: an epigenetic and environmental viewpoint
    K.Iwata, H.Matsuzaki, N.Takei, T.Manabe, N.Mori
    Journal of Central Nervous System Disease. 2 37-44 Nov.  2010 Refereed
  • Failure to confirm genetic association of the FXYD6 gene with schizophrenia: The Japanese population and meta-analysis
    Y.Iwata, K.Yamada, Y. Iwayama, A.Anitha, I.Thanseem, T.Toyota, E.Hattori, T.Ohnishi, M.Maekawa, K.Nakamura, K.Suzuki, H.Matsuzaki, KJ.Tsuchiya, S.Suda, G.Sugihara, K.Takebayashi, S.Yamamoto, K.Iwata, N.Mori, T.Yoshikawa
    Am J Med Genet B Neuropsychiatr Genet. 153B(6) 1221-1227 Sep.  2010 Refereed
  • Reduced expression of apolipoprotein E receptor type 2 in peripheral blood lymphocytes from patients with major depressive disorder
    K.Suzuki, Y.Iwata, H.Matsuzaki, A.Anitha, S.Suda, K.Iwata, C.Shinmura, Y.Kameno, KJ.Tsuchiya, K.Nakamura, N.Takei, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 34(6) 1007-1010 Aug.  2010 Refereed
  • Decreased serum levels of adiponectin in subjects with autism
    A.Fujita-Shimizu, K.Suzuki, K.Nakamura, T.Miyachi, H.Matsuzaki, M.Kajizuka, C.Shinmura, Y.Iwata, S.Suda, KJ.Tsuchiya, K.Matsumoto, G.Sugihara, K.Iwata, S.Yamamoto, M.Tsujii, T.Sugiyama, N.Takei, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 34(3) 455-458 Apr.  2010 Refereed
  • Destruction of dopaminergic neurons in the midbrain by 6-hydroxydopamine decreases hippocampal cell proliferation in rats: reversal by fluoxetine
    K.Suzuki, K.Okada, T.Wakuda, C.Shinmura, Y.Kameno, K.Iwata, T.Takahashi, S.Suda, H.Matsuzaki, Y.Iwata, K.Hashimoto, N.Mori
    PLoS One. 5(2) e9260 Feb.  2010 Refereed
  • Serum levels of platelet-derived growth factor BB homodimers are increased in male children with autism
    M.Kajizuka, T.Miyachi, H.Matsuzaki, K.Iwata, C.Shinmura, K.Suzuki, S.Suda, KJ.Tsuchiya, K.Matsumoto, Y.Iwata, K.Nakamura, M.Tsujii, T.Sugiyama, N.Takei, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 34(1) 154-158 Feb.  2010 Refereed
  • Further evidence for the role of MET in autism susceptibility
    I.Thanseem, K.Nakamura, T.Miyachi, T.Toyota, S.Yamada, M.Tsujii, KJ.Tsuchiya, A.Anitha, Y. Iwayama, K.Yamada, E.Hattori, H.Matsuzaki, K.Matsumoto, Y.Iwata, K.Suzuki, S.Suda, M.Kawai, GI.Sugihara, K.Takebayashi, N.Takei, H.Ichikawa, T.Sugiyama, T.Yoshikawa, N.Mori
    Neurosci Res. 68(2) 137-141 Jan.  2010 Refereed
  • Brain Serotonin and Dopamine Transporter Bindings in Adults with High-Functioning Autism
    K.Nakamura, Y.Sekine, Y.Ouchi, M.Tsujii, E,Yoshikawa, M.Futatsubashi, KJ.Tsuchiya, G.Sugihara, K.Nishimura, K.Takebayashi, M.Kawai, Y.Iwata, K.Suzuki, S.Suda, H.Matsuzaki, S.Yamamoto, K.Matsumoto, T.Sugiyama, N.Takei, N.Mori
    Arch. Gen. Psychiatry. 67(1) 59-68 Jan.  2010 Refereed
  • Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder
    A.Anitha, K.Nakamura, K.Yamada, Y.Iwayama, T.Toyota, N.Takei, Y.Iwata, K.Suzuki, Y.Sekine, H.Matsuzaki, M.Kawai, I.Thanseem, K.Miyoshi, T.Katayama, S.Matsuzaki, K.Baba, A.Honda, T.Hattori, S.Shimizu, N.Kumamoto, M.Kikuchi, M.Tohyama, T.Yoshikawa, N,Mori
    Am J Med Genet B Neuropsychiatr Genet. 150B(7) 967-976 Jan.  2009 Refereed
  • Genetic and expression analyses reveal elevated expression of syntaxin 1A (STX1A) in high functioning autism
    K.Nakamura, A.Anitha, K.Yamada, M.Tsujii, Y.Iwayama, E.Hattori, T.Toyota, S.Suda, N.Takei, Y.Iwata, K.Suzuki, H.Matsuzaki, M.Kawai, Y.Sekine, KJ.Tsuchiya, GI.Sugihara, Y.Ouchi, T.Sugiyama, T.Yoshikawa, N.Mori
    Int J Neuropsychopharmacol. 11(8) 1073-1084 Dec.  2008 Refereed
  • Perinatal asphyxia reduces dentate granule cells and exacerbates methamphetamine-induced hyperlocomotion in adulthood
    T.Wakuda, H.Matsuzaki, K.Suzuki, Y.Iwata, C.Shinmura, S.Suda, K.Iwata, S.Yamamoto, G.Sugihara, KJ.Tsuchiya, T.Ueki, K.Nakamura, D.Nakahara, N.Takei, N.Mori
    PLoS One. 3(11) e3648 Nov.  2008 Refereed
  • Irradiation in adulthood as a new model of schizophrenia
    Y.Iwata, K.Suzuki, T.Wakuda, N.Seki, I.Thanseem, H.Matsuzaki, T.Mamiya, T.Ueki, S.Mikawa, T.Sasaki, S.Suda, S.Yamamoto, KJ.Tsuchiya, G.Sugihara, K.Nakamura, K.Sato, N.Takei, K.Hashimoto, N.Mori
    PLoS One. 3(5) e2283 May  2008 Refereed
  • Methamphetamine causes microglial activation in the brains of human abusers
    Y.Sekine, Y.Ouchi, G.Sugihara, N.Takei, E.Yoshikawa, K.Nakamura, Y.Iwata, KJ.Tsuchiya, S.Suda, K.Suzuki, M.Kawai, K.Takebayashi, S.Yamamoto, H.Matsuzaki, T.Ueki, N.Mori, MS.Gold, JL.Cadet
    J Neurosci. 28(22) 5756-5761 May  2008 Refereed
  • Gene and expression analyses reveal enhanced expression of pericentrin 2 (PCNT2) in bipolar disorder
    A.Anitha, K.Nakamura, K.Yamada, Y.Iwayama, T.Toyota, N.Takei, Y.Iwata, K.Suzuki, Y.Sekine, H.Matsuzaki, M.Kawai, K.Miyoshi, T.Katayama, S.Matsuzaki, K.Baba, A.Honda, T.Hattori, S.Shimizu, N.Kumamoto, M.Tohyama, T.Yoshikawa, N.Mori
    Biol Psychiatry. 63(7) 678-685 Apr.  2008 Refereed
  • Serum levels of P-selectin in men with high-functioning autism
    Y.Iwata, KJ.Tsuchiya, S.Mikawa, K.Nakamura, Y.Takai, S.Suda, Y.Sekine, K.Suzuki, M.Kawai, G.Sugihara, H.Matsuzaki, K.Hashimoto, M.Tsujii, T.Sugiyama, N.Takei, N.Mori
    Br J Psychiatry. 193(4) 338-339 Jan.  2008 Refereed
  • Paternal age at birth and high-functioning autistic-spectrum disorder in offspring
    KJ.Tsuchiya, K.Matsumoto, T.Miyachi, M.Tsujii, K.Nakamura, S.Takagai, M.Kawai, A.Yagi, K.Iwaki, S.Suda, G.Sugihara, Y.Iwata, H.Matsuzaki, Y.Sekine, K.Suzuki, T.Sugiyama, N.Mori, N.Takei
    Br J Psychiatry. 193(4) 316-321 Jan.  2008 Refereed
  • Genetic analyses of Roundabout (ROBO) axon guidance receptors in autism
    A.Anitha, K.Nakamura, K.Yamada, S.Suda, I.Thanseem, M.Tsujii, Y.Iwayama, E.Hattori, T.Toyota, T.Miyachi, Y.Iwata, K.Suzuki, H.Matsuzaki, M.Kawai, Y.Sekine, K.Tsuchiya, GI.Sugihara, Y.Ouchi, T.Sugiyama, K.Koizumi, H.Higashida, N.Takei, T.Yoshikawa, N.Mori
    Am J Med Genet B Neuropsychiatr Genet. 147B(7) 1019-1027 Jan.  2008 Refereed
  • Decreased expression of reelin receptor VLDLR in peripheral lymphocytes of drug-naive schizophrenic patients
    K.Suzuki, K.Nakamura, Y.Iwata, Y.Sekine, M.Kawai, G.Sugihara, KJ.Tsuchiya, S.Suda, H.Matsuzaki, N.Takei, K.Hashimoto, N.Mori
    Schizophr Res. 98(42007) 148-156 Jan.  2008 Refereed
  • Decreased serum levels of PECAM-1 in subjects with high-functioning autism: a negative correlation with head circumference at birth
    KJ.Tsuchiya, K.Hashimoto, Y.Iwata, M.Tsujii, Y.Sekine, G.Sugihara, H.Matsuzaki, S.Suda, M.Kawai, K.Nakamura, Y.Minabe, A.Yagi, M.Iyo, N.Takei, N.Mori
    Biol Psychiatry. 62(9) 1056-1058 Nov.  2007 Refereed
  • SNP analyses of growth factor genes EGF, TGF-β1, and HGF reveal haplotypic association of EGF with autism
    T.Toyoda, K.Nakamura, K.Yamada, I.Thanseem, A.Anitha, S.Suda, M.Tsujii, Y.Iwayama, E.Hattori, T.Toyota, T.Miyachi, Y.Iwata, K.Suzuki, H.Matsuzaki, M.Kawai, Y.Sekine, K.Tsuchiya, GI.Sugihara, Y.Ouchi, T.Sugiyama, N.Takei, T.Yoshikawa, N.Mori
    Biochem Biophys Res Commun. 360(4) 715-720 Sep.  2007 Refereed
  • Decreased serum levels of epidermal growth factor in adult Subjects with high-functioning autism
    K.Suzuki, K.Hashimoto, Y.Iwata, K.Nakamura, M.Tsujii, KJ.Tsuchiya, Y.Sekine, S.Suda, G.Sugihara, H.Matsuzaki, T.Sugiyama, M.Kawai, Y.Minabe, N.Takei, N.Mori
    Biol Psychiatry. 62(3) 267-269 Aug.  2007 Refereed
  • Disruption of Reelin signaling attenuates methamphetamine-induced hyperlocomotion
    H.Matsuzaki, Y.Minabe, K.Nakamura, K.Suzuki, Y.Iwata, Y.Sekine, KJ.Tsuchiya, G.Sugihara, S.Suda, N.Takei, D.Nakahara, K.Hashimoto, AC.Nairn, N.Mori, K.Sato
    Eur. J. Neurosci. 25(11) 3376-3384 Jun.  2007 Refereed
  • Genetic analyses of the brain-derived neurotrophic factor (BDNF) gene in autism
    K.Nishimura, K.Nakamura, A.Anitha, K.Yamada, M.Tsujii, Y.Iwayama, E.Hattori, T.Toyota, N.Takei, T.Miyachi, Y.Iwata, K.Suzuki, H.Matsuzaki, M.Kawai, Y.Sekine, K.Tsuchiya, G.Sugihara, S.Suda, Y.Ouchi, T.Sugiyama, T.Yoshikawa, N.Mori
    Biochem Biophys Res Commun. 356(1) 200-206 Apr.  2007 Refereed
  • Decreased serum levels of hepatocyte growth factor in male adults with high-functioning autism
    G.Sugihara, K.Hashimoto, Y.Iwata, K.Nakamura, M.Tsujii, KJ.Tsuchiya, Y.Sekine, K.Suzuki, S.Suda, H.Matsuzaki, M.Kawai, Y.Minabe, A.Yagi, N.Takei, T.Sugiyama, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 31(2) 412-415 Mar.  2007 Refereed
  • Linkage disequilibrium analysis of the CHRNA7 gene and its partially duplicated region in schizophrenia
    Y.Iwata, M.Nakajima, K.Yamada, K.Nakamura, Y.Sekine, KJ.Tsuchiya, G.Sugihara, H.Matsuzaki, S.Suda, K.Suzuki, N.Takei, N.Mori, Y.Iwayama, H.Takao, T.Yoshikawa, B.Riley, A.Makoff, P.Sham, R.Chen, D.Collier
    Neurosci Res. 57(2) 194-202 Feb.  2007 Refereed
  • Increased levels of serum soluble L-selectin in unmedicated patients with schizophrenia
    Y.Iwata, K.Suzuki, K.Nakamura, H.Matsuzaki, Y.Sekine, KJ.Tsuchiya, G.Sugihara, M.Kawai, Y.Minabe, N.Takei, N.Mori
    Schizophr Res. 89(42007) 154-160 Jan.  2007 Refereed
  • Decreased serum levels of transforming growth factor-beta1 in patients with autism
    K.Okada, K.Hashimoto, Y.Iwata, K.Nakamura, M.Tsujii, KJ.Tsuchiya, Y.Sekine, S.Suda, K.Suzuki, G.Sugihara, H.Matsuzaki, T.Sugiyama, M.Kawai, Y.Minabe, N.Takei, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 31(1) 187-190 Jan.  2007 Refereed
  • Increased serum levels of glutamate in adult patients with autism
    A.Shinohe, K.Hashimoto, K.Nakamura, M.Tsujii, Y. Iwata, KJ.Tsuchiya, Y.Sekine, S.Suda, K.Suzuki, G.Sugihara, H.Matsuzaki, Y.Minabe, T.Sugiyama, M.Kawai, M.Iyo, N.Takei, N.Mori
    Prog Neuropsychopharmacol Biol Psychiatry. 30(8) 1472-1477 Dec.  2006 Refereed
  • Gaze recognition in high-functioning autistic patients: evidence from functional MRI
    H.Takebayashi, H.Matsumoto, M.Ogai, Y.Sekine, K.Suzuki, H.Matsuzaki, J.Suckling, F.Ozawa, R.Fukuda, I.Uchiyama, K.Nakamura, Y.Minabe, H. Isoda, N.Mori, N.Takei
    Chiba medical journal 82 139-147 Nov.  2006 Refereed
  • An association study between COMT gene polymorphism and methamphetamine psychotic disorder
    A.Suzuki, K.Nakamura, Y.Sekine, Y.Minabe, N.Takei, K.Suzuki, Y.Iwata, M.Kawai, K.Takebayashi, H.Matsuzaki, M.Iyo, N.Ozak, T.Inada, N.Iwata, M.Harano, T.Komiyama, M.Yamada, I.Sora, H.Ujike, N.Mori
    Psychiatric Genetics 16(4) 133-138 Aug.  2006 Refereed
  • Brain derived neurotrophic factor rescues neuronal death induced by methamphetamine
    H.Matsuzaki, K.Namikawa, H.Kiyama, N.Mori, K.Sato
    Biol Psychiatry 55(1) 52-60 Jan.  2004 Refereed
  • Developmental changes in KCC1, KCC2, and NKCC1 mRNA expressions in the rat brain
    C.Wang, C.Shimizu-Okabe, K.Watanabe, A.Okabe, H.Matsuzaki, T.Ogawa, N.Mori, A.Fukuda, K.Sato
    Dev. Brain Res. 139 59-66 Nov.  2002 Refereed
  • Vascular Endothelial Growth Factor Rescues Hippocampal Neurons from Glutamate-Induced Toxicity: Signal Transduction Cascades
    H.Matsuzaki, M.Tamatani, A.Yamaguchi, K.Namikawa, H.Kiyama, M.P.Vitek, N.Mitsuda, M.Tohyama
    FASEB J. 15(7) 1218-1220 Jun.  2001 Refereed
  • Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53
    A.Yamaguchi, M.Tamatani, H.Matsuzaki, K.Namikawa, H.Kiyama, M.P.Vitek, N.Mitsuda, M.Tohyama
    J. Biol. Chem. 276(7) 5256-5264 Feb.  2001 Refereed
  • A Pathway of Neuronal Apoptosis Induced by Hypoxia/Reoxygenation: Roles of Nuclear Factor-kB and Bcl-2
    M.Tamatani, N.Mitsuda, H.Matsuzaki, H.Okado, S.Miyake, M.P.Vitek, A.Yamaguchi, M.Tohyama
    J. Neurochem. 75(2) 683-693 Aug.  2000 Refereed
  • Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons
    H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, M.Tohyama
    J. Neurochem. 73(5) 2037-2046 Nov.  1999 Refereed
  • Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkB activation in primary hippocampal neurons
    M.Tamatani, Y.H.Che, H.Matsuzaki, S.Ogawa, H.Okado, S.Miyake, T.Mizuno, M.Tohyama
    J. Biol. Chem. 274(13) 8531-8538 Mar.  1999 Refereed
  • Anti-inflammatory effect of ghrelin in lymphoblastoid cell lines from children with autism spectrum disorder.
    Y.Yamashita, M.Makinodan, M.Toritsuka, T.Yamauchi, D.Ikawa, S.Kimoto, T.Komori, R.Takada, Y.Kayashima, K.Hamano-Iwasa, M.Tsujii, H.Matsuzaki and T.Kishimoto. 
    Front Psychiatry 10 152 Mar.  2019 Refereed
  • PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.
    MJ.Xie, Y.Ishikawa, H.Yagi, T.Iguchi, Y.Oka, K.Kuroda, K.Iwata, H.Kiyonari, S.Matsuda, H.Matsuzaki, M.Yuzaki, Y.Fukazawa and M.Sato.
    Sci Rep. 9(1) 4305 Mar.  2019 Refereed
  • Altered gene expression in lymphoblastoid cell lines after subculture.
    M.Toritsuka, M.Makinodan, T.Yamauchi, Y.Yamashita, D.Ikawa, T.Komori, S.Kimoto, K.Hamano-Iwasa, H.Matsuzaki and T.Kishimoto.
    In Vitro Cell. Dev. Biol. Anim. 54(7) 523-527 Jun.  2018 Refereed

Conference Activities & Talks

  • Measurement of Multiple Radical Scavenging Activity as a diagnostic method for autism spectrum disorder in children.
    A,Hirayama, H.Matsuzaki
    The Society for Redox Biology and Medicine’s 23rd Annual Meeting Nov.  2016 Society for Redox Biology and Medicine
  • Specific Hypolipidemia caused by VLDL degradation in Children with ASD.
    H.Matsuzaki, K.Iwata, K.Nakamura, M.Tsujii, N.Mori
    The Society for Neuroscience 46th annual meeting Nov.  2016 Society for Neuroscience
  • Phosphoinositide responsive Phldb2 regulates synaptic plasticity.
    MJ.Xie, H.Yagi, T.Iguchi, Y.Oka, Y.Fukazawa, H.Matsuzaki, K.Iwata, Y.Ishikawa, M.Sato
    The Society for Neuroscience 46th annual meeting Nov.  2016 Society for Neuroscience
  • NSF interact with SEAT and modulates its trafficking : implications for path ophysiology in autism.
    K.Iwata, H.Matsuzaki, K.Tachibana, K.Nakamura, T.Katayama, N.Mori
    Neuroscience 2015 Oct.  2015
  • Perturbation on the mouse maternal gut microbiota during pregnancy leads to the abnormal behavior of their offspring
    S.Tochitani, H.Matsuzaki
     Jul.  2015
  • Abnormal Expression of a SERT-Binding Protein, NSF, in Autism: Implications for Pathophysiology in Autism
    K.Iwata, H.Matsuzaki, K.Nakamura, T.Katayama, N.Mori
    2015 International Meeting for Autism Research May  2015
  • Modulation of the serotonin transporter by interaction with N-ethylmaleimide-sensitive factor.
    K.Iwata, H.Matsuzaki, T.Tachibana, T.Katayama, N.Mori
    2014 International Meeting for Autism Research May  2014
  • Specific Hypolipidemia Caused By VLDL Lipolysis in Children with ASD.
    H.Matsuzaki, K. Iwata, K.Nakamura, M,Tsujii, N.Mori
    2014 International Meeting for Autism Research May  2014
  • Alteration of the expression balance of hnRNP C1 and C2 changes the expression of myelination- and schizophrenia-related genes in the human oligodendrocytic cell line.
    K.Iwata, H.Matsuzaki, T.Manabe, D.Martins-de-Souza, N.Takei
    SIRS2014(The 4th Biennial Schizophrenia International Research Society Conference) Apr.  2014
  • Modulation of the serotonin transporter by interaction with N-ethylmaleimide-sensitive factor.
    K. Iwata, H.Matsuzaki, T.Tachibana, T.Katayama, N.Mori
    Neuro2013 Jun.  2013
  • Specific hypolipidemia pattern in individuals with autism spectrum disorder.
    H.Matsuzaki, K. Iwata, T.Tachibana, T.Katayama, N.Mori
    11th World Congress of Biological Psychiatry Jun.  2013
  • Genome-wide DNA methylation profiles in post-mortem brains from subjects with autism.
    K. Iwata, K.Nakamura, H.Matsuzaki, K.Nakamura, K.Hata, N.Mori
    International Meeting for Autism Research May  2013
  • Genome-wide DNA methylation profiles in post-mortem brains from subjects with autism.
    K. Iwata, H.Matsuzaki, K.Nakabayashi, K.Nakamura, K.Hata, N.Mori
    The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry Sep.  2012
  • Serum levels of anterior pituitary hormones in children with autism.
    K. Iwata, H.Matsuzaki, N.Mori
    The 11th annual International Meeting for Autism Research May  2012
  • Serum levels of anterior pituitary hormones in children with autism.
    H.Matsuzaki, K. Iwata, N.Mori
    The 11th annual International Meeting for Autism Research May  2012
  • Serum levels of anterior pituitary hormones in children with autism. the 54th Annual.
    H.Matsuzaki, K.Iwata, N.Mori
    Meeting of the Japanese Society for Neurochemistry Sep.  2011
  • Alteration of the expression balance of hnRNP C1 and C2 changes the expression of myelination-related genes in the human neuroblastoma cell line.
    K.Iwata, H.Matsuzaki, N.Mori
    the 54th Annual Meeting of the Japanese Society for Neurochemistry Sep.  2011
  • Enhanced Expression of Transcription Factor Sp1 in Postmortem Brain Tissues and Altered Regulation of Several Autism Candidate Genes.
    I.Thanseem, A.Anitha, K.Nakamura, S.Suda, H.Matsuzaki, N.Mori
    XIXth World Congress of Psychiatric Genetics Sep.  2011
  • Assisted reproduction and compromised social responsiveness among 14-month-old infants: the Hamamatsu Birth Cohort (HBC) Study.
    KJ.Tsuchiya, K.Matsumoto, H.Matsuzaki, Y.Nakamura, H.Itoh, N.Takei, the HBC Study Team
    The 7th World Congress on Developmental Origins of Health and Disease Sep.  2011
  • VLDL-specific hypolipidemia pattern in human subjects with autism and autistic rodent models.
    H.Matsuzaki, K.Iwata, KJ.Tsuchiya, H.Itoh, N.Mori
    The 7th World Congress on Developmental Origins of Health and Disease Sep.  2011
  • Brain serotonin and dopamine transporter bindings in adults with autism.
    K.Nakamura, Y.Iwata, N.Mori, G.Sugihara, Y.Ouchi, M.Tsujii, T.Sugiyama, KJ.Tsuchiya, K.Suzuki, H.Matsuzaki, S.Suda, N.Takei
    The Society for Neuroscience 40th annual meeting Nov.  2010
  • Dysregulation of glutamatergic biosynthetic pathway in subjects wuth autism.
    C.Shimmura, S.Suda, KJ.Tsuchiya, K.Hashimoto, K.Ohno, H.Matsuzaki, K.Iwata, Y.Kameno, K.Nakamura, N.Takei, N.Mori
    The Society for Neuroscience 40th annual meeting Nov.  2010
  • Serum adipokine levels in children with autism.
    H.Matsuzaki, A.Fujita-Shimizu, K.Iwata, S.Suda, C.Shimmura, Y.Kameno, N.Mori
    The Society for Neuroscience 40th annual meeting Nov.  2010
  • VLDLR-overexpressing transgenic rats: evaluation as an animal models of autism.
    K.Iwata, H.Matsuzaki, N.Izumo, Y.Ichitani, N.Takei, N.Mori
    The Society for Neuroscience 40th annual meeting Nov.  2010
  • VLDLR overexpression rat: evaluation as an animal model of autism.
    K.Iwata, H.Matsuzaki, N.Izumo, Y.Ichitani, N.Mori
    The 53rd Annual Meeting of the Japanese Society for Neurochemistry, Sep.  2010
  • Serum adipokine levels in children with autism.
    H.Matsuzaki
    The 53rd Annual Meeting of the Japanese Society for Neurochemistry Sep.  2010
  • Brain Serotonin and Dopamine Transporter Bindings in Adults with Autism.
    K.Nakamura, Y.Ouchi, M.Tsujii, KJ.Tsuchiya, G.Sugihara, Y.Iwata, K.Suzuki, H.Matsuzaki, S.Suda, T.Sugiyama, N.Takei, N.Mori
    The 9th annual International Meeting for Autism Research May  2010
  • Dyslipidemia in male patients with high-functioning autism.
    H.Matsuzaki, K.Iwata, S.Suda, KJ.Tsuchiya, K.Suzuki, K.Nakamura, M.Tsujii, N.Takei, N.Mori
    The 9th annual International Meeting for Autism Research May  2010
  • Perinatal asphyxia attenuates hippocampal neurogenesis and enhances methamphetamine -induced locomotion in adult rats.
    T.Wakuda, H.Matsuzaki, M.Dote, Y.Iwata, K.Suzuki, N.Mori
    The 32nd Annual Meeting of the Japanese Society of Biological Psychiatry Jan.  2010
  • Lipid metabolism analysis of serum in male with autism.
    H.Matsuzaki, K.Iwata, A.Fujita-Shimizu, N.Mori
    The 32nd Annual Meeting of the Japanese Society of Biological Psychiatry Jan.  2010
  • A perspective of biological marker research for Autism.
    H.Matsuzaki
    The 52nd Annual Meeting of the Japanese Society for Neurochemistry Jun.  2009
  • Genetic and Expression Analyses of Serotonergic Factors in Autism.
    K.Nakamura, T.Miyachi, A.Ayyappan, M.Tsujii, S.Suda, I.Thanseem, K.Tsuchiya, H.Matsuzaki, K.Yamada, Y.Iwayama, T.Toyota, E.Hattori, T.Sugiyama, N.Takei, T.Yoshikawa, N.Mori
    The 8th Annual International Meeting For Autism Research May  2009
  • Serotonin related gene expression changes in subjects with autism: A postmortem brain study.
    S.Suda, K.Iwata, A.Anitha, I.Thanseem, H.Matsuzaki, Y.Kameno, K.Nakamura, N.Mori, N.Takei
    The Society for Neuroscience 39th annual meeting Jan.  2009
  • Dyslipidemia in male patients with high-functioning autism.
    H.Matsuzaki, K.Iwata, S.Suda, T.Miyachi, K.Suzuki, K.Nakamura, M.Tsujii, N.Takei, N.Mori
    The Society for Neuroscience 39th annual meeting Jan.  2009
  • Wide-spread decreases of serum growth factors levels in male with high-functioning autism.
    H.Matsuzaki, Y.Iwata, JK.Tsuchiya, G.Sugihara, S.Suda, K.Suzuki, K.Nakamura, M.Tsujii, N.Takei, K.Hashimoto, N.Mori
    The 38th annual meeting of the Society for Neuroscience Nov.  2008
  • Serotonin transporter and serotonin related gene expression in autism.
    S.Suda, K.Iwata, A.Anitha, I.Thanseem, K.Nakamura, H.Matsuzaki, Y.Iwata, S.Yamamoto, K.Suzuki, N.Takei, K.Koizumi, N.Mori
    The 38th annual meeting of the Society for Neuroscience Nov.  2008
  • The trial to establish novel animal model for autism by focusing on reelin signal.
    H.Matsuzaki, K.Iwata, K.Takebayashi, G.Sugihara, K.Suzuki, K.Nakamura, M.Kawai, M.Tsujii, N.Takei, N.Mori
    The 35th annual meetings of Japan Brain Science Society Jun.  2008
  • Genetic analyses of serotonergic factors in autism.
    H.Matsuzaki, K.Nakamura, M.Tsujii, A.Ayyappan, K.Yamada, S.Suda, Y.Iwayama, T.Miyachi, KJ.Tsuchiya, T.Sugiyama, N.Takei, T.Yoshikawa, N.Mori
    The 7th annual International Meeting for Autism Research May  2008
  • Decreased serum levels of growth factors in male adults with high-functioning autism.
    H.Matsuzaki, Y.Iwata, KJ.Tsuchiya, G.Sugihara, S.Suda, K.Suzuki, T.Miyachi, K.Matsumoto, K.Nakamura, M.Kawai, M.Tsujii, T.Sugiyama, N.Takei, N.Mori
    The 7th annual International Meeting for Autism Research May  2008
  • Neurogenesis correlates sensorimotor gating via activation of hippocampal Akt.
    H.Matsuzaki, T.Wakuda, Y.Iwata, N.Seki, K.Suzuki, S.Suda, N.Takei, M.Tohyama, N.Mori
    The Society for Neuroscience 37th annual meeting Nov.  2007
  • Neurogenesis correlates sensorimotor gating via activation of hippocampal Akt.
    H.Matsuzaki, T.Wakuda, N.Seki, Y.Iwata, K.Suzuki, N.Takei, M.Tohyama, N.Mori
    The 50th annual meetings of Japanese Society for Neurochemistry Sep.  2007
  • Decreased serum levels of growth factors in adult subjects with high-functioning autism.
    H.Matsuzaki, Y.Iwata, KJ.Tsuchiya, G.Sugihara, S.Suda, K.Suzuki, K.Nakamura, N.Takei, K.Hashimoto, N.Mori
    The 29th Annual Meeting of the Japanese Society of Biological Psychiatry Jul.  2007
  • The trial to establish novel therapy for schizophrenia by modification of neurogenesis.
    T.Wakuda, H.Matsuzaki, Y.Iwata, N.Seki, K.Suzuki, N.Takei, M.Tohyama, N.Mori
    The 29th Annual Meeting of the Japanese Society of Biological Psychiatry Jul.  2007
  • Increased serum levels of glutamate in adult patients with autism.
    A.Shinohe, K.Hashimoto, K.Nakamura, M.Tsujii, Y.Iwata, H.Matsuzaki, T.Sugiyama, M.Iyo, N.Takei, N.Mori
    The 34th annual meetings of Japan Brain Science Society Jun.  2007
  • Perinatal asphyxia attenuates hippocampal neurogenesis and enhances methamphetamine-induced locomotion in adult rats.
    T.Wakuda, H.Matsuzaki, M.Dote, Y.Iwata, K.Suzuki, M.Tohyama, N.Mori
    The 34th annual meetings of Japan Brain Science Society Jun.  2007
  • The trial to establish novel therapy for schizophrenia by modification of neurogenesis.
    H.Matsuzaki, T.Wakuda, M.Dote, Y.Iwata, K.Suzuki, M.Tohyama, N.Mori
    The 34th annual meetings of Japan Brain Science Society Jun.  2007
  • Chronic psychostimulant administration reduces Akt protein levels in irradiated rat hippocampus.
    H.Matsuzaki, Y.Iwata, T.Wakuda, T.Watanabe, K.Suzuki, N.Takei, M.Tohyama, N.Mori
    The Society for Neuroscience 36th annual meeting Nov.  2006
  • Increased serum levels of glutamate in adult patients with autism.
    A.Shinohe, K.Hashimoto, K.Nakamura, M.Tsujii, Y.Iwata, H.Matsuzaki, T.Sugiyama, M.Iyo, N.Takei, N.Mori
    The 28th Annual Meeting of the Japanese Society of Biological Psychiatry Sep.  2006
  • Perinatal asphyxia-exposed rat as animal model for schizophrenia.
    T.Wakuda, T.Watanabe, Y.Iwata, H.Matsuzaki, K.Suzuki, N.Takei, N.Mori
    The 28th Annual Meeting of the Japanese Society of Biological Psychiatry Sep.  2006
  • Reduction of hippocampal AKT caused by chronic psychostimulant administration in irradiated rats.
    H.Matsuzaki, Y.Iwata, T.Wakuda, T.Watanabe, K.Suzuki, N.Takei, M.Tohyama, N.Mori
    The 49th annual meetings of Japanese Society for Neurochemistry Sep.  2006
  • Akt transgene trial for therapy of schizophrenia.
    H.Matsuzaki, Y.Iwata, HH.Dang, M.Tohyama, N.Mori
    The 33th annual meetings of Japan Brain Science Society Jun.  2006
  • cAMP Mediated Changes in AMPA Receptor Dynamics Dependent on Epac.
    D.D.Kiraly, P.Olausson, H.Matsuzaki, A.C.Nairn, J.R.Taylor
    The Society for Neuroscience 35th annual meeting Nov.  2005
  • Epac-specific cAMP analogue induces GluR1 and NR2B degradation via calpain activation in hippocampus.
    H.Matsuzaki, P.Olausson, D.D.Kiraly, J.R.Taylor, A.C.Nairn
    The Society for Neuroscience 35th annual meeting Nov.  2005
  • Epac-specific cAMP analogue induces GluR1 and NR2B degradation via calpain activation in hippocampus.
    H.Matsuzaki, P.Olausson, D.D.Kiraly, J.R.Taylor, A.C.Nairn, N.Mori
    The 48th annual meetings of Japanese Society for Neurochemistry Sep.  2005
  • Disruption of Reelin signal reduces dopamine function in the adult mouse brain.
    Y.Minabe, H.Matsuzaki, K.Hashimoto, K.Suzuki, D.Nakahara, N.Mori, K.Sato
    The Society for Neuroscience 33th annual meeting Nov.  2003
  • BDNF inhibits apoptosis induced by methamphetamine in primary cortical neurons through activation of Akt kinase.
    H.Matsuzaki, K.Namikawa, H.Kiyama, N.Mori, K.Sato
    The 45th annual meetings of Japanese Society for Neurochemistry Jul.  2002
  • BDNF inhibits apoptosis induced by methamphetamine in primary cortical neurons through Activation of Akt kinase.
    H.Matsuzaki, Y.Minabe, N.Mori, K.Sato
    The Society of Biological Psychiatry 57th Annual Meeting May  2002
  • Activation of Akt kinase inhibits p53-mediated neuronal death through phosphorylation of the p53-binding protein, 53BP1.
    H.Matsuzaki, M.Tamatani, A.Yamaguchi, K.Iwabuchi, M.Tohyama
    The 106th annual meeting of the Japanese Association of Anatomists Apr.  2001
  • Vascular endothelial growth factor has neuroprotective effect through Akt and ERK activation.
    H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, A.Yamaguchi, M.Tohyama
    The 23rd annual meeting of Japan Neuroscience Society Sep.  2000
  • Akt activation inhibits p53-induced neuronal cell death.
    A.Yamaguchi, M.Tamatani, H.Matsuzaki, K.Namikawa, H.Kiyama, N.Mitsuda, M.Tohyama
    The 23rd annual meeting of Japan Neuroscience Society Sep.  2000
  • VEGF and neuroprotection.
    H.Matsuzaki
    The 41st Senri neuroscience meeting Jul.  2000
  • Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons.
    H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, M.Tohyama
    The 105th annual meeting of the Japanese Association of Anatomists Mar.  2000
  • Activation of NFkB inhibits neuronal apoptosis induced by Hypoxia/Reoxia.
    M.Tamatani, H.Matsuzaki, N.Mitsuda, H.Okado, A.Yamaguchi, S.Miyake, M.Tohyama
    The 105th annual meeting of the Japanese Association of Anatomists Mar.  2000
  • Akt activation inhibits transcriptional activity of p53.
    A.Yamaguchi, M.Tamatani, H.Matsuzaki, N.Mitsuda, K.Namikawa, H.Kiyama, T.Suzuki, M.Tohyama
    The 105th annual meeting of the Japanese Association of Anatomists Mar.  2000
  • Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1.
    N.Mitsuda, N.Okubo, M.Tamatani, A.Yamaguchi, H.Matsuzaki, S.Miyake, T.Hagiwara, M.Tohyama
    The 105th annual meeting of the Japanese Association of Anatomists Mar.  2000
  • Vascular endothelial growth factor has neuroprotective effect through Akt activation.
    Y.Bando, H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, M.Tohyama
    The 105th annual meeting of the Japanese Association of Anatomists Mar.  2000
  • Vascular endothelial growth factor has neuroprotective effect through Akt and ERK activation.
    H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, A.Yamaguchi, M.Tohyama
    The 43rd annual meetings of Japanese Society for Neurochemistry Jan.  2000
  • Akt activation inhibits p53-induced neuronal cell death.
    A.Yamaguchi, M.Tamatani, H.Matsuzaki, K.Namikawa, H.Kiyama, N.Mitsuda, M.Tohyama
    The 43rd annual meetings of Japanese Society for Neurochemistry Jan.  2000
  • Activation of NFkB inhibits neuronal apoptosis induced by Hypoxia/Reoxia.
    M.Tamatani, H.Matsuzaki, A.Yamaguchi, H.Okado, S.Miyake, M.Tohyama
    The 42nd annual meetings of Japanese Society for Neurochemistry Sep.  1999
  • Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons.
    H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, M.Tohyama
    The 42nd annual meetings of Japanese Society for Neurochemistry Sep.  1999
  • The neuroprotective effect of tumor necrosis factor.
    T.Mizuno, M.Tamatani, H.Matsuzaki, Y.H.Che, A.Yamaguchi, S.Miyake, M.Tohyama
    The 42nd annual meetings of Japanese Society for Neurochemistry Sep.  1999
  • Tumor necrosis factor induces Bcl-2 expression through NFkB activation in primary hippocampal neurons.
    T.Mizuno, M.Tamatani, H.Matsuzaki, Y.H.Che, S.Miyake, M.Tohyama
    The 22nd annual meeting of Japan Neuroscience Society Jul.  1999
  • Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons.
    H.Matsuzaki, M.Tamatani, N.Mitsuda, K.Namikawa, H.Kiyama, S.Miyake, M.Tohyama
    The 22nd annual meeting of Japan Neuroscience Society Jul.  1999
  • The mechanism of neuronal cell death by hypoxia: Roles of Bcl-2 family and ORP150.
    M.Tamatani, S.Ogawa, Y.H.Che, K.Ozawa, H.Matsuzaki, S.Miyake, H.Okado, M.Tohyama
    The 22nd annual meeting of Japan Neuroscience Society Jul.  1999
  • NO-induced neuronal cell death and neuroprotective effect of IGF-1.
    H.Matsuzaki
    The 34th Senri neuroscience meeting May  1999
  • Tumor necrosis factor induces Bcl-2 expression through NFkB activation in primary hippocampal neurons.
    H.Matsuzaki, M.Tamatani, S.Ogawa, Y.H.Che, S.Miyake, M.Tohyama
    The 104th annual meeting of the Japanese Association of Anatomists Mar.  1999
  • Abnormal membrane protein trafficking in the autistic like the N-ethylmaleimide sensitive factor knockout mice.
    MJ.Xie, K.Iwata, Y.Fukazawa and H.Matsuzaki
    The Society for Neuroscience 48th annual meeting Nov.  2018

Patents

  • Patent8518659:Method and marker for determination of degree of risk of onset of high-functioning autism
    特願13/501147
    特開US2012/0231484 A1
    特番8518659
    高機能自閉症,中性脂肪