KIMURA Hirohiko

FacultyRadiology and Laboratory Medicine, Radiology
Teacher OrganizationRadiology and Laboratory Medicine
Education and
 Research Organization
Faculty of Medical Sciences, School of Medicine
Last Updated: 20/07/06 11:51

Researcher Profile & Settings


    KIMURA Hirohiko


  •  Radiology and Laboratory Medicine, Radiology Professor

Research Activities

Published Papers

  • Serial changes of (18)F-FDG PET/CT findings in ischiopubic synchondrosis: comparison with contrast-enhanced MRI.
    Tsuji K, Tsuchida T, Kosaka N, Tanizawa A, Kimura H.
    Hellenic Journal of Nuclear Medicine 18(1) 66-67 Mar.  2015 Refereed
  • Standardized uptake value differences between primary and metastatic lesions in 18F-FDG PET/CT of patients with lung cancer.
    N Kosaka, T Tsuchida, K Tsuji, K Shimizu, H Kimura
    Acta Radiol 56(11) 1329-1335 Nov.  2015 Refereed
  • Fat-subtracted three-dimensional time-of-flight MR angiography of the neck by use of fat-only images with the two-point Dixon technique.
    Y Fujiwara, Y Ishimori, I Yamaguchi, N Kosaka, H Kimura, T Adachi
    Radiol Phys Technol 8(2) 193-199 Jul.  2015 Refereed
  • Comparison of long-labeled pseudo-continuous arterial spin labeling (ASL) features between young and elderly adults: special reference to parameter selection.
    Y Fujiwara, T Matsuda, M Kanamoto, T Tsuchida, K Tsuji, N Kosaka, T Adachi, H Kimura
    Acta Radiol 58(1) 84-90 Jan.  2017 Refereed
  • Evaluation of staging and early response to chemotherapy with whole-body diffusion-weighted magnetic resonance imaging in malignant lymphoma patients: A comparison with FDG-PET/CT
    K Tsuji, S Kishi, T Tsuchida, T Yamauchi, S Ikegaya, Y Urasaki, Y Fujiwara, T Ueda, H Okazawa, H Kimura
    J Magn Reson Imaging 41(6) 1601-1607 Jun.  2015 Refereed
  • Alpha 1-Adrenoceptor Blocker May Improve Not Only Voiding But Also Storage Lower Urinary Tract Symptoms Caused by 125I Brachytherapy for Prostate Cancer
    N.Oyama, Y.Aoki, H.Ito, Y.Miwa, H.Akino, Y.Sato, H.Shioura, H.Kimura, O.Yokoyama
     Mar.  2014 Refereed
  • Assessment of tumor blood flow and its correlation with histopathologic features in skull base meningiomas and schwannomas by using pseudo-continuous arterial spin labeling images
    Yamamoto T, Takeuchi H, Kinoshita K, Kosaka N, Kimura H
    European Journal of Radiology Epub 2014 Feb 6. Feb.  2014 Refereed
  • Arterial spin labeling perfusion-weighted MRI for long-term follow-up of a cerebral arteriovenous malformation after stereotactic radiosurgery
    Kazuhiro Shimizu, Nobuyuki Kosaka, Tatsuya Yamamoto, Hiroki Shioura, Toshiaki Kodera, Ken-ichiro Kikuta, Hirohiko Kimura
    Acta Radiologica Short Reports 3(1) 2.05E+15 Jan.  2014 Refereed
  • Detection of preclinically latent hyperperfusion due to stroke-like episodes by arterial spin-labeling perfusion MRI in MELAS patients
    M.Ikawa, M.Yoneda, T.Muramatsu, A.Matsunaga, T.Tsujikawa, T.Yamamoto, N.Kosaka, K.Kinoshita, O.Yamamura, T.Hamano, Y.Nakamoto, H.Kimura
     13(6) 676-680 Nov.  2013 Refereed
  • A rare congenital anomaly, bridge-like appendiceal fistula to the terminal ileum, demonstrated by MDCT
    Takeuchi K, Kosaka N, Kinoshita K, Sakai T, Sawai K, Imamura Y, Kimura H
    Surgical and radiologic anatomy 35(6) 523-527 Aug.  2013 Refereed
  • hin-slice CT findings of biliary stricture due to blunt abdominal trauma: reports of three cases
    N.Muraoka, T.Sakai, K.Koneri, Y.Imamura, H.Kimura
    Jpn J Radiol 31(7) 500-504 Jul.  2013 Refereed
  • Hashimoto’s encephalopathy with hippocampus involvement detected on continuous arterial spin labeling
    M.Ishitobi, M.Yoneda, M.Ikawa, A.Matsunaga, K.Ueno, H.Kimura, Y.Wada
    Psychiatry and Clinical Neurosciences 67(2) 128-9 Feb.  2013 Refereed
  • Monitoring of extra-axial brain tumor response to radiotherapy using pseudo-continuous arterial spin labeling images: Preliminary results
    Yamamoto T, Kinoshita K, Kosaka N, Sato Y, Shioura H, Takeuchi H, Kimura H
    Magn Reson Imaging 31(8) 1271-1277 Jan.  2013 Refereed
  • Oestrogen-related tumour phenotype: PET characterisation with 18F-FDG and 18F-FES
    T.Tsujikawa, Y.Yoshida, H.Maeda, T.Tsuchida, T.Mori, Y.Kiyono, H.Kimura, H.Okazawa
     85(1015) 1020-1024 Jun.  2012 Refereed
  • MR perfusion imaging by alternate slab width inversion recovery arterial spin labeling(AIRASL) : a technique with higher signal-to-noise ratio at 3.0T
    Yasuhiro Fujiwara, Hirohiko Kimura, Toshiaki Miyati, Hiroyuki Kabasawa, Tsuyoshi Matsuda, Yoshiyuki Ishimori, Isao Yamaguchi, Toshiki Adachi
    Magnetic Resonance Materials in physics Biology and Medicine 25(2) 103-111 Apr.  2012 Refereed
  • First description of the role of 18F-FDG-PET/CT as compared to CT, MRI to suspect a case of thymoma in a pediatric patient
    T. Tsuchida, S. Kinoshita, A. Kawakita, M. Yasutomi, A. Tanizawa, H. Kimura
    Hell J Nucl Med 15(1) 68-69 Mar.  2012 Refereed
  • Optimizing scan timing of hepatic arterial phase by physiologic pharmacokinetic analysis in bolus-tracking technique by multi-detector row computed tomography
    Isao Yamaguchi, Eiji Kidoya, Masayuki Suzuki, Hirohiko Kimura
     4 43-52 Jan.  2011 Refereed
  • Acoustic Noise Transfer Function in Clinical MRI
    Takashi Hamaguchi, Tosiaki Miyati, Naoki Ohno, Masaya Hirano, Norio Hayashi, Toshifumi Gabata, Osamu Matsui, Tatsuhiko Matsushita, Tomoyuki Ymamoto, Yasuhiro Fujiwara, Hirohiko Kimura, Hiroyasu Takeda, Yasuo Takehara
     18(1) 101-106 Jan.  2011 Refereed
  • Embolic infarction followed by serial bone SPECT and MR fusion images-the door to SPECT/MR
    T. Tsujikawa, T. Kamibayashi, T. Tsuchida, Y. Ohkoshi, H. Kimura
     57(3,4) 334-337 Aug.  2010 Refereed
  • Posterior reversible encephalopathy syndrome following measles vaccination
    Tadanori Hamano, Tomoko Takeda, Hiroshi Morita, Tomoko Muramatsu, Makoto Yoneda, Hirohiko Kimura, Masaru Kuriyama
     2010 Refereed
  • Application of a multifractal analysis to study brain white matter abnormalities of schizophrenia on T2-weighted magnetic resonance imaging
    T.Takahashi, H.Kosaka, T.Murata, M.Omori, K.Narita, H.Mitsuya, K.Takahashi, H.Kimura, Y.Wada
     171(3) 177-188 Mar.  2009 Refereed
  • The Effectiveness of 18F-FDG PET/CT combined with STIR MRI for diagnosing nodal involvement in the thorax
    M.Morikawa, Y.Demura, T.Ishizaki, S.Ameshima, I.Miyamori, M.Sasaki, T.Tsuchida, H.Kimura, Y.Fujibayashi, H.Okazawa
    J Nucl Med 50(1) 81-87 Jan.  2009 Refereed
  • Evaluation of required saline volume in dynamic contrast-enhanced computed tomography using saline flush technique
    Isao Yamaguchi, Eiji Kidoya, Masayuki Suzuki, Hirohiko Kimura
    Computerized Medical Imaging and Graphics 33(1) 23-28 Jan.  2009 Refereed
  • Evaluation of required saline volume in dynamic contrast-enhanced computed tomography using saline flush technique
    I..Yamaguchi, E.Kidoya, M.Suzuki, H.Kimura
    Computerized medical imaging and graphics 33(1) 23-28 Nov.  2008 Refereed
  • 18F-FDG PET of common enhancing malignant brain tumors
    N.Kosaka, T.Tsuchida, H. Uematsu, H.Kimura, H.Okazawa, H.Itoh
    Am J Roentgenol 190(6) W365-W369 Jun.  2008 Refereed
  • Operation of bolus traking system for prediction of aortic peak enhancement at multidetector row computed tomography:
    I.Yamaguchi, H.Hayashi, M.Suzuki, K.Ichikawa, E.Kidoya, H.Kimura
    Radiation Medicine 26(5) 278-286 Jun.  2008 Refereed
  • Rare Causes of Hematuria Associated with Various Vascular Diseases Involving the Upper Urinary Tract
    N.Muraoka, T.Sakai, H.Kimura, H. Uematsu, K.Tanase, O.Yokoyama, H.Itoh
     May  2008 Refereed
  • Reproducibility of Semi-quantitative Parameters in FDG-PET Using Two Different PET Scanners: Influence of Attenuation Correction Method and Examination Interval
    T.Kamibayashi, T.Tsuchida, Y.Demura, T.Tsujikawa, H.Okazawa, T.Kudo, H.Kimura
    Mol Imaging Biol. 10(3) 162-166 May  2008 Refereed
  • Rate of liver volume increase: can it predict recipient prognosis after left lobe transplantation from living related donors?
    N.Muraoka, H. Uematsu, H.Kimura, T.Sakai, T.Takeda, K.Kinoshita, H.Matsunami, H.Itoh
     Apr.  2008 Refereed
  • Apparent Diffusion Coefficient in Pancreatic Cancer: Characterization and Histopathological Correlations
    N.Muraoka, H. Uematsu, H.Kimura, Y.Imamura, Y.Fujiwara, M.Murakami, A.Yamaguchi, H.Itoh
     2008 Refereed
  • Tissue characterization of glioma by proton magnetic resonance spectroscopy and perfusion-weighted magnetic resonance imaging: glioma grading and histological correlation
    M.Toyooka, H.Kimura, H. Uematsu, Y.Kawamura, H.Takeuchi, H.Itoh
     2008 Refereed
  • Intrathoracic Benign Goiter Imaged by F-18-FDG-PET A Case Report
    S Wakahara, T Konoshita, A Sakai, T Nakaya, M Ichikawa, K Yamamoto, M Imagawa, H Kimura, H Ozawa, T Ishizuka
    MEDICINE 94(32) 1-3 Aug.  2015 Refereed
  • Development of an Magnetic Resonance Imaging Safety Management System for Metallic Biomedical Products Using an Magnetic Resonance Compatibility Database and Inquiry-based Patient Records
    Fujiwara Yasuhiro;Kata Tomomi;Fujimoto Shinichi;Yachida Takuya;Kanamoto Masayuki;Nanbu Yousuke;Seki Kouichirou;Kosaka Nobuyuki;Kimura Hirohiko;Adachi Toshiki
    Jpn. J. Radiol. Technol. 70(12) 1413-1419 Dec.  2014
    Several incidents involving magnetic resonance imaging (MRI) examinations of patients with unchecked MR-unsafe metallic products have been reported. To improve patient safety, we developed a new MRI safety management system for metallic biomedical products and evaluated its efficiency in clinical practice. Our system was integrated into the picture archiving and communication system (PACS) and comprised an MR compatibility database and inquiry-based patient records of internal metallic biomedical products, enabling hospital staff to check MR compatibility by product name. A total of 6,637 biomedical implants and devices were listed in this system, including product names and their MR compatibilities. Furthermore, MRI histories for each patient at our hospital were also recorded. Using this system, it was possible to confirm the MR compatibility of the patients' metallic biomedical products effectively and to reduce the number of unchecked internal products through systematic patient inquiry. In conclusion, our new system enhanced metallic biomedical product checking procedures, and improved patient safety during clinical MRI examinations.
  • Assessing Tumor Hypoxia in Head and Neck Cancer by PET With Cu-62-Diacetyl-Bis(N-4-Methylthiosemicarbazone)
    Sato, Yoshitaka;Tsujikawa, Tetsuya;Oh, Myungmi;Mori, Tetsuya;Kiyono, Yasushi;Fujieda, Shigeharu;Kimura, Hirohiko;Okazawa, Hidehiko
    CLINICAL NUCLEAR MEDICINE 39(12) 1027-1032 2014
  • Assessment of tumor blood flow and its correlation with histopathologic features in skull base meningiomas and schwannomas by using pseudo-continuous arterial spin labeling images
    Yamamoto, Tatsuya;Takeuchi, Hiroaki;Kinoshita, Kazuyuki;Kosaka, Nobuyuki;Kimura, Hirohiko
    EUROPEAN JOURNAL OF RADIOLOGY 83(5) 817-823 2014
  • A case of interval form of carbon monoxide poisoning without increased carboxyhemoglobin level diagnosed by characteristic MR spectroscopy findings
    Kamisawa Tomoko;Ikawa Masamichi;Hamano Tadanori;Nagata Miwako;Kimura Hirohiko;Yoneda Makoto
    Rinsho Shinkeigaku 54(3) 234-237 2014
    A 67-year-old man living alone was admitted for acute disturbance of consciousness during winter. He presented with semicoma, a decorticate posture, and exaggerated tendon reflexes of the limbs, but brainstem reflexes were intact. The carboxyhemoglobin (COHb) level was normal in arterial blood gas on admission, and protein in cerebrospinal fluid was increased without pleocytosis. Brain MRI showed diffuse T2 high intensities in the deep white matter bilaterally without a contrast effect and abnormal T1 intensity in the pallidum. 1H-MR spectroscopy (MRS) of the white matter lesion demonstrated findings suggesting demyelination as an increased choline peak, enhanced anaerobic metabolism as increased lactate and lipids peaks, and reduced neurons as a decreased N-acetylaspartate peak, which corresponded to delayed encephalopathy due to the interval form of carbon monoxide (CO) poisoning. The possibility of CO exposure due to coal briquette use 2 weeks before the symptomatic onset was indicated by his family, so he was diagnosed with CO poisoning. His consciousness slightly improved with corticosteroid therapy and repetitive hyperbaric oxygen therapy, but brain MRI and MRS findings did not improve. Characteristic MRS findings of leukoencephalopathy are helpful for diagnosing the interval form of CO poisoning in the case of a normal COHb level.
  • Feasibility of liver weight estimation by postmortem computed tomography images: An autopsy study
    Inai, Kunihiro;Noriki, Sakon;Kinoshita, Kazuyuki;Nishijima, Akihiko;Sakai, Toyohiko;Kimura, Hirohiko;Naiki, Hironobu
    PATHOLOGY INTERNATIONAL 64(7) 315-324 Jul.  2014
  • Arterial Transit Time-corrected Renal Blood Flow Measurement with Pulsed Continuous Arterial Spin Labeling MR Imaging
    K Shimizu, N Kosaka, Y Fujiwara, T Matsuda,T Yamamoto, T Tsuchida, K Tsuchiyama, N Oyama, H Kimura
    Magn Reson Med Sci 16(1) 38-44 Jan.  2017 Refereed
    Purpose: The importance of arterial transit time (ATT) correction for arterial spin labeling MRI has been well debated in neuroimaging, but it has not been well evaluated in renal imaging. The purpose of this study was to evaluate the feasibility of pulsed continuous arterial spin labeling (pcASL) MRI with multiple post-labeling delay (PLD) acquisition for measuring ATT-corrected renal blood flow (ATC-RBF).Materials and Methods: A total of 14 volunteers were categorized into younger (n = 8; mean age, 27.0 years) and older groups (n = 6; 64.8 years). Images of pcASL were obtained at three different PLDs (0.5, 1.0, and 1.5 s), and ATC-RBF and ATT were calculated using a single-compartment model. To validate ATC-RBF, a comparative study of effective renal plasma flow (ERPF) measured by 99mTc-MAG3 scintigraphy was performed. ATC-RBF was corrected by kidney volume (ATC-cRBF) for comparison with ERPF.Results: The younger group showed significantly higher ATC-RBF (157.68 ± 38.37 mL/min/100 g) and shorter ATT (961.33 ± 260.87 ms) than the older group (117.42 ± 24.03 mL/min/100 g and 1227.94 ± 226.51 ms, respectively; P < 0.05). A significant correlation was evident between ATC-cRBF and ERPF (P < 0.05, r = 0.47). With suboptimal single PLD (1.5 s) settings, there was no significant correlation between ERPF and kidney volume-corrected RBF calculated from single PLD data.Conclusion: Calculation of ATT and ATC-RBF by pcASL with multiple PLD was feasible in healthy volunteers, and differences in ATT and ATC-RBF were seen between the younger and older groups. Although ATT correction by multiple PLD acquisitions may not always be necessary for RBF quantification in the healthy subjects, the effect of ATT should be taken into account in renal ASL–MRI as debated in brain imaging.
  • Assessment of the tumor redox status in head and neck cancer by 62Cu-ATSM PET.
    T Tsujikawa, S Asahi, M Oh, Y Sato, N Narita, A Makino, Y Kiyono, T Tsuchida, H Kimura, S Fujieda , H Okazawa
    PLoS ONE 11(5) e0155635 May  2016 Refereed
  • Arterial transit time mapping obtained by pulsed continuous 3D ASL imaging with multiple post-label delay acquisitions: Comparative study with PET-CBF in patients with chronic occlusive cerebrovascular disease.
    T Tsujikawa, H Kimura, T Matsuda, Y Fujiwara, M Isozaki, K Kikuta, H Okazawa
    PLoS ONE 11(6) e0156005 Jun.  2016 Refereed
  • Postmortem CT is more accurate than clinical diagnosis for identifying the immediate cause of death in hospitalized patients: a prospective autopsy-based study.
    K Inai,S Noriki, K Kinoshita,T Sakai,H Kimura,A Nishijima,H Iwasaki ,H Naiki
    Virchows Archiv : an international journal of pathology 469(1) 101-109 Jul.  2016 Refereed
    :Despite 75 to 90 % physician accuracy in determining the underlying cause of death, precision of determination of the immediate cause of death is approximately 40 %. In contrast, two thirds of immediate causes of death in hospitalized patients are correctly diagnosed by postmortem computed tomography (CT). Postmortem CT might provide an alternative approach to verifying the immediate cause of death. To evaluate the effectiveness of postmortem CT as an alternative method to determine the immediate cause of death in hospitalized patients, an autopsy-based prospective study was performed. Of 563 deaths from September 2011 to August 2013, 50 consecutive cadavers undergoing hospital autopsies with consent for additional postmortem CT at the University of Fukui were enrolled. The accuracy of determination of the immediate cause of death by postmortem CT was evaluated in these patients. Diagnostic discrepancy was also compared between radiologists and attending physicians. The immediate cause of death was correctly diagnosed in 37 of 50 subjects using postmortem CT (74 %), concerning 29 cases of respiratory failure, 4 of hemorrhage, 3 of liver failure and 1 of septic shock. Six cases of organ failure involving 13 patients were not identified as the cause of death by postmortem CT. Regarding the immediate cause of death, accuracy of clinical diagnosis was significantly lower than that of postmortem CT (46 vs 74 %, P < 0.01). Postmortem CT may be more useful than clinical diagnosis for identifying the immediate cause of death in hospitalized patients not undergoing autopsy.
  • Newly recognized cerebral infarctions on postmortem imaging: a report of three cases with systemic infectious disease
    BMC Med Imaging 17(1) 4 Jan.  2017 Refereed
  • Long-Term Endoscopic Follow-Up of Patients with Chronic Radiation Proctopathy after Brachytherapy for Prostate Cancer.
    Diagn Ther Endosc 2016 Jun.  2016 Refereed
  • Muscle MRI of the Upper Extremity in the Myotonic Dystrophy Type 1
    European neurology 76(1-2) 87-94 Jul.  2016 Refereed
  • Pituitary metastasis of hepatocellular carcinoma presenting with panhypopituitarism: a case report
    BMC Cancer 15 863-863 Nov.  2015 Refereed
  • Three-dimensional arterial spin labeling imaging with a DANTE preparation pulse
    T.Matsuda, H.Kimura. H.Kabasawa, M.Kanamoto
    Magn Reson Imaging 49 131-137 Feb.  2018 Refereed
  • Evaluation of obliteration of arteriovenous malformations after stereotactic radiosurgery with arterial spin labeling MR imaging
    T.Kodera, Y.Arai, H.Arishima, Y.Higashino, M.Isozaki, K.Tsunetoshi, K.Matsuda, R.Kitai, K.Shimizu, N.Kosaka, T.Yamamoto, H.Shioura, H.Kimura, KI.Kikuta
    Br J Neurosurg 31(6) 641-647 Dec.  2017 Refereed
  • Evaluation of bleb fluid after baerveldt glaucoma implantation using magnetic resonance imaging
    K.Iwasaki, M.Kanamoto, Y.Takihara, S.Arimura, Y.Takamura, H.Kimura, M.Inatani
    Sci Rep 7(1) Sep.  2017 Refereed
  • Comparison of AAPM addendum to TG-51,IAEA TRS-398,and JSMP 12:Calibration of photon beams in water
    N.Kinoshita, H.Oguchi, Y.Nishimoto, T.Adachi, H.Shioura, H.Kimura, K.Doi
    J Appl Clin Med Phys 18(5) 271-278 Sep.  2017 Refereed
  • Assessment of intratumor heterogeneity in mesenchymal uterine tumor by an (18)F-FDG PET/CT texture analysis
    Tsujikawa T, Yamamoto M, Shono K, Yamada S, Tsuyoshi H, Kiyono Y, Kimura H, Okazawa H, Yoshida Y
    Ann Nucl Med 31(10) 752-757 Sep.  2017 Refereed
  • 18F-FDG PET radiomics approaches: comparing and clustering features in cervical cancer
    Tsujikawa T, Rahman T, Yamamoto M, Yamada S, Tsuyoshi H, Kiyono Y, Kimura H, Yoshida Y, Okazawa H
    Ann Nucl Med 31(9) 678-685 Nov.  2017 Refereed
  • Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation
    Okazawa H, Higashino Y, Tsujikawa T, Arishima H, Mori T, Kiyono Y, Kimura H, Kikuta K
    Eur J Radiol 105 102-109 Jun.  2018 Refereed
  • Selected PET radiomic features remain the same
    T.Tsujikawa, H.Tsuyoshi, M.Kanno, S.Yamada, M.Kobayashi, N.Narita, H.Kimura S.Fujieda, Y.Yoshida, H.Okazawa
    Oncotarget 9(29) 20734-20746 Apr.  2018 Refereed
  • Feasibility of Arterial Spin Labeling MR Imaging for Detecting Cerebellar Hypoperfusion in Patients with Spinocerebellar Degeneration
    Ikawa, Masamichi;Kimura, Hirohiko;Kitazaki, Yuki;Matsunaga, Akiko;Hayashi, Koji;Yamamura, Osamu;Hamano, Tadanori;Yoneda, Makoto;Okazawa, Hidehiko;Nakamoto, Yasunari
    NEUROLOGY 90 Apr.  2018
  • The present state of radiation exposure from pediatric CT examinations in Japan-what do we have to do?
    R.Ideguchi, K.Yoshida, A.Ohtsuru, N.Takamura, T.Tsuchida, H.Kimura, M.Uetani, T.Kudo
    J Radiat Res 59(suppl_2) ii 130-ii 136 Apr.  2018 Refereed
  • Uncertainty in positioning ion chamber at reference depth for various water phantoms
    N.Kinoshita, H.Oguchi, T.Adachi, H.Shioura, H.Kimura
    Rep Pract Oncol Radiother 23(3) 199-206 May  2018 Refereed
  • Evaluation of retained products of conception using pulsed continuous arterial spin-labeling MRI: clinical feasibility and initial results
    N.Kosaka, Y.Fujiwara, T.Kurokawa, T.Matsuda, M.Kanamoto, N.Takei, K.Takata, J.Takahashi, Y.Yoshida, H.Kimura
    MAGMA 31(4) 577-584 Aug.  2018 Refereed
  • Pseudo-continuous arterial spin labeling MR images in Warthin tumors and pleomorphic adenomas of the parotid gland: qualitative and quantitative analyses and their correlation with histopathologic and DWI and dynamic contrast enhanced MRI findings
    T.Yamamoto, H.Kimura, K.Hayash, Y.Imamura, M.Mori
    Neuroradiology 60(8) 803-812 Aug.  2018 Refereed
  • Arterial spin labeling MR imaging for the clinical detection of cerebellar hypoperfusion in patients with spinocerebellar degeneration
    M.Ikawa, H.Kimura, Y.Kitazaki, K.Sugimoto, A.Matsunaga, K.Hayashi, O.Yamamura, T.Tsujikawa, T.Hamano, M.Yoneda, H. Okazawa, Y.Nakamoto
    J Neurol Sci 394 58-62 Nov.  2018 Refereed
  • Influence of myocardial count on phase dyssynchrony analysis of gated myocardial perfusion single-photon emission computed tomography
    A.Kita, M.Onoguchi, T.Shibutani, K.Sugimoto, N Kosaka, T.Adachi, H.Kimura
    Nucl Med Commun 40(2) 124-130 Feb.  2019 Refereed
  • The use of combined T2-weighted and FLAIR synthetic magnetic resonance images to improve white matter region contrast: a feasibility study
    Y.Fujiwara, Y.Inoue, M.Kanamoto, S.Ishida, T.Adachi, H.Kimura
    Radiol Phys Technol 12(1) 118-125 Mar.  2019 Refereed
  • 深層学習を用いた胸部X線画像からの解剖学的構造の領域検出
     56(6) 243-251 Dec.  2018 Refereed
  • Whole-body bone marrow DWI correlates with age, anemia, and hematopoietic activity.
    T.Tsujikawa, H.Oikawa, T.Tasaki, N.Hosono, H.Tsuyoshi, Y.Yoshida, T.Yamauchi, H.Kimura, H.Okazawa
    Eur J Radiol. 118 223-230 Sep.  2019 Refereed
  • Pathological analysis of cadavers for educational dissection by using postmortem imaging
    S.Noriki, S.Iino, K.Kinoshita, Y.Fukazawa, K.Inai, T.Sakai, H.Kimura
    Pathol int 69(10) 580-600 Oct.  2019 Refereed
  • FDG-PET/CT findings of hepatic tumor and tumor-like lesions based on molecule background
    Kumi Ozaki, Kenichi Harada, Norihide Yoneda,Osamu Matsui, Hirohiko Kimura, Toshifumi Gabata
    Radiological Society of North America 2019会議論文 Dec.  2019 Refereed
  • Pearls and pitfalls of imaging features of pancreatic cystic lesions: a case-based approach
    Kumi Ozaki, Kazuya Maeda, Yasuharu Kaizaki,Hirohiko Kimura, Toshifumi Gabata
    Radiological Society of North America 2019 Dec.  2019 Refereed
  • Serial Brain MRI Changes Related to Autoimmune Pathophysiology in Hashimoto Encephalopathy With anti-NAE Antibodies: A Case-Series Study
    A.Matsunaga, M.Ikawa ,Y.Kawamura, T,Kishitani, O.Yamamura, T.Hamano, H.Kimura, Y.Nakamoto, M.Yoneda
    J Neurol Sci 406 Nov.  2019 Refereed

Conference Activities & Talks

  • Clinical Applications of Multidisciplinary Computational Anatomy to Diagnosis -Plan of Five years and Progress Overview FY2016-
    S kido, N Hashimoto, Y hirano, S Mabu, H Kim, H Kimura, S Noriki, K Inai
    Proceedings of the Third Iinternational Symposium on the Project Multidisciplinary Computational Anatomy Mar.  2017
  • Evaluation of 3D-TOF-MRA of the Head combined usage with Parallel Imaging and Compressed Sensing on 3T MRI
    M Kanamoto, Y Fujiwara, N Takei, T Yamamoto, T Miyati, T Adachi, H Kabasawa, H Kimura
    International Society for Magnetic Resonance in Medicine (ISMRM) 24th Annual Meeting &Exhibition May  2016
  • Tissue assessment in gliomas: comparison of tumorblood volume, permeability by perfusion-weighted MR imaging and Tl-201 SPECT
    H. Uematsu, T. Tsuchida, H. Kimura, N. Kosaka, H. Itoh
     Jun.  2007
  • Cerebral perfusion measurements using continuous arterial spin labeling (CASL): Transit time measurements of normal subjects.
    H.Kimura, KH.abasawa, H. Uematsu, Y.Koshimoto, Y.Kawamura, H.Itoh
    European Congress of Radiology Mar.  2005
  • Cerebral perfusion measurements using continuous arterial spin labeling(CASL)-transit time measurements of normal subjects.
    Kimura H, kabaswa H, Yonekura Y, Itoh H
    The Third International Workshop on Biomedical Imaging Dec.  2004
  • New quality assurance systems for the evaluation of detectability of lung nodules on the digital chest radiograph.
    fujiwara H, Kimura H, Higashimura K, Itoh H
    European Congress of Radiology Mar.  2004
  • Cerebral perfusion measurements using continuous arterial spin labeling (CASL): Accuracy and Limits of Quantitative Approach.
    Kimura H, Kabasawa H, Yonekura Y, Itoh H
    International Workshop on Quantitation in Biomedical Imaging with PET and MRI Jan.  2004
  • Clinical magnetic resonance spectroscopy (MRS) revisited: Useful cases and reviews.
    Kimura H, Koshimoto Y, Uematsu H, Yamada H, kawamura Y, itoh H
    The Radiological Society of North America, Scientific Assembly and Annual Meeting Nov.  2003
  • Radiological significance of the brain dock for the prevention of cerebral stroke: comparison with radiological findings and the natural course after brain dock.
    kado H, Shimosegawa E, Kimura H, Hatazawa J, Ogawa T
    The Radiological Society of North America, Scientific Assembly and Annual Meeting Nov.  2003
  • Development of an intelligent digital view box with the function of self-learning in the process of film reading.
    Tanaka M, Kimura H, Yonekura Y, Itoh H
    The Radiological Society of North America, Scientific Assembly and Annual Meeting Nov.  2003
  • Perfusion imaging of meningioma using continuous arterial spin labeling (CASL): Comparison with histopathological features.
    Kimura H, Takeuchi H, Koshimoto Y, Kado H, Kubota T, Itoh H
    ISMRM eleventh Scientific meeting and Exhibition, Toronto, Ontario, Canada. Jul.  2003
  • The Results from Pre-Phase 2 Clinical Trial with a Novel Trimeric Gadlinium MRI Contrast Agent-NMS60.
    kawamura Y, Kimura H, Koshimoto Y, Itoh H, Seri S
    ISMRM eleventh Scientific meeting and Exhibition Jul.  2003
  • Clinical Application of Proton MR Spectroscopy for Detecting Thalamic Abnormalities in
    Kado H, Kimura H, Omori M, Mutata T, SAhimosegawa E, wada Y, Itoh H
    ISMRM eleventh Scientific meeting and Exhibition Jul.  2003
  • Technical and theoretical basis of perfusion MRI.
    Hirohiko Kimura
    International Neuro Imaging Symposium, Jun.  2003
  • 脳分子イメージングによるMELAS脳卒中様発作の病態解明
    米田 誠,井川 正道,辻川 哲也,木村 浩彦,岡沢 秀彦
     Nov.  2016
  • Negative‐FLAIR画像を呈した心原性脳塞栓例のCASL画像による発症時期との相関について
    北﨑 佑樹,山村 修,山口 智久,遠藤 芳徳,岸谷 融,白藤 法道,松永 晶子,林 浩嗣,山元 龍哉,,木村 浩彦,濱野 忠則
     May  2015
  • Arterial spin labeling perfusion imaging: can we say it is quantitative?
    The 6th international congress on magnetic resonance imaging & 23th annual scientific meeting of KSMRM(ICMRI2018) Mar.  2018
  • Arterial transit time measured by multi-delay ASL perfusion for evaluating major cerebral artery stenosis/occlusive disease: correlation with 15O-H2O and 15O2 gas PET-CBF and OEF
    K.Takeuchi, M.Isozaki, M.Kanamoto, Y.Higashino, H.Okazawa, KI.Kikuta, R.Marc Lebel, H.Kimura
    ISMRM 25th Annual Meeting & Exhibition International Society for Magnetic Resonance in Medicine Apr.  2017
  • Molecular brain imaging evaluates the pathophysiology of stroke-like episodes in MELAS
    Yoneda M, Ikawa M, Tsujikawa T, Kimura H, Okazawa H
    World Congress of Neurology Sep.  2017
  • Assessment of intratumor heterogeneity in mesenchymal uterine tumor by FDG-PET/CT texture analysis.
    Tsujikawa T, Yamamoto M, Shono K, Yamada S, Kimura H, Okazawa H, Yoshida Y
     Apr.  2017
  • Practical parameter setting for simultaneous measurement of CBF and ATT with Hadamard-encoded ASL: Special reference for clinical practice
    S.Ishida, H.Kimura, N.Takei, M.Kanamoto, Y.Fujiwara, T. Matsuda, Marc R Lebel, T.Adachi
    Joint Annual meeting ISMRM-ESMRMB Jun.  2018
  • Free Breathing Multiple delays renal perfusion MRI using hadamard encoded pCASL
    N.Takei, S.Ishida, N.Kosaka, R Marc Lebel, Y.Matta, H.Kimura, H.kabasawa
    Joint Annual Meeting ISMRM-ESMRMB 2018 Jun.  2018
  • Comparison of different technique in myocardial T1 value measurement
    Japanese Journal of Magnetic Resonance in Medicine Sep.  2018
  • The simultanous calculation of CBF and arterial CBV based on ASL signal obtained with and without vessel suppression
    H.kimura, S.Ishida, T.Matsuda, N.Takei, Y.Fujiwara, N.kosaka
    Japanese Journal of Magnetic Resonance in Medicine Sep.  2018
  • Non-contrast perfusion technique developments for assessing hemodynamics in patients with chronic occlusive cerebrovascular disease
    SIGNATM Masters 2018 Asia Neuro Summit Oct.  2018
  • Anatomical borderline structure detection in chest X-ray by deep neural networks
    S.Fujimoto, K.Kondo, H.Itoh, H.Kimura, T.Adachi, M.Kiyono, M. Tanaka, J.Ozawa
    Radiological Society of North America 104th scientific assembly and annual meeting RSNA2018 Nov.  2018
  • Selected PET radiomic features remain the same - Clinical validation with PET/CT & PET/MRI -
    Tsujikawa T, Tsuyoshi H, Kannno M, Yamada S, Kobayashi M, Narita N, Kimura H, Fujieda S, Yoshida Y, Okazawa H
    The 77th Annual Meeting of the Japan Radiological Society Apr.  2018
  • Whole-body bone marrow DWI correlates with age, anemia, and hematopoietic activity
    Tsujikawa T, Oikawa H, Tasaki T, Hosono N, Tsuyoshi H, Yoshida Y, Yamauchi T, Kimura H, Okazawa H
     Apr.  2019
  • Direct comparison of factors related to bone marrow FDG uptake and MR signals using integrated PET/MRI
    Tsujikawa T, Oikawa H, Tasaki T, Hosono N, Yamauchi T, Kimura H, Okazawa H
     May  2019
  • Morphometric changes and imaging findings of diffuse liver disease in relation to intrahepatic hemodynamics
    K.Ozaki, K.Kozaka, H.Kimura, T.Gabata, O.Matsui
    Radiological Society of North America 2019 (RSNA) Dec.  2019
  • Pearls and pitfalls of imaging features of pancreatic cystic lesions: a case-based approach
    K.Ozaki, K.Maeda, Y.Kaizaki, H.Kimura, T.Gabat
    Radiological Society of North America 2019 (RSNA) Dec.  2019
  • FDG-PET/CT findings of hepatic tumor and tumor-like lesions based on molecule background
    K.Ozaki, K.Harada, N.Yoneda, H.Kimura, T.Gabata, O.Matsui
    Radiological Society of North America 2019 (RSNA) Dec.  2019
  • Robust arterial transit time estimation using combined acquisition of Hadamard-encoded pCASL and long-labeled long-delay pCASL: a simulation and in vivo study
    S.Ishida, H.Kimura, N.Takei, Y.Fujiwara, T.Matsuda, M.Kanamoto, N.Kosaka, R Marc Lebel, T.Adachi
    ISMRM 27th Annual Meeting May  2019

Awards & Honors

  •  Radiological Society of North America Certificate of Merit Morphometric changes and imaging findings of diffuse liver disease in relation to intrahepatic hemodynamicsDec. 2019

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