Jung Minyoung

FacultyGeneral Medicine, Neuropsychiatry
Teacher OrganizationGeneral Medicine
Education and
 Research Organization
Faculty of Medical Sciences, School of Medicine
PositionSenior Assistant Professor
Last Updated: 20/05/22 11:49

Researcher Profile & Settings

Name

    Jung Minyoung

Profile & Settings

Affiliation

  •  General Medicine, Neuropsychiatry Senior Assistant Professor
  •  Research Center for Child Mental Development Senior Assistant Professor

Education

  • Apr. 2013Mar. 2015Osaka University 小児発達
  • Apr. 2011Mar. 2013University of Tsukuba 障害科学
  • Mar. 2004Feb. 2009Daegu Univiersity (Korea) Rehabilitation Science

Academic & Professional Experience

  • Aug. 2015Aug. 2017Harvard medical school Department of Psychiatry (Massachusetts General Hospital) Research Fellow

Research Activities

Published Papers

  • The Dysfunction of the Cerebellum and Its Cerebellum-Reward-Sensorimotor Loops in Chronic Spontaneous Urticaria.
    Wang Y, Fang J, Song P, Bao Y, Song W, Liu J, Lang C, Jorgenson K, Jung M, Shen D, Li S, Sun R, Ding X, Yang J, Meng X, Wang N, Yan Z, Yan Y, Kong Q, Dong Y, Cui F, Tu Y, Cui B, Kong J.
    Cerebellum 17(5) 507-516 Oct.  2018 Refereed
  • Surface-based shared and distinct resting functional connectivity in attention-deficit hyperactivity disorder and autism spectrum disorder
    Jung Minyoung;Tu Yiheng; Park Joel; Jorgenson Kristen; Lang Courtney; Song Wenwen; Kong Jian
    The British Journal of Psychiatry 214(6) 339-344 Jun.  2019 Refereed
  • The Effects of COMT Polymorphism on Cortical Thickness and Surface Area Abnormalities in Children with ADHD.
    Jung M;Mizuno Y;Fujisawa T X;Takiguchi S;Kong J;Kosaka H;Tomoda A
    Cerebral cortex 29(9) 3902-3911 Aug.  2019 Refereed
  • Symptoms in individuals with adult-onset ADHD are masked during childhood.
    Kosaka Hirotaka;Fujioka Toru;Jung Minyoung
    European archives of psychiatry and clinical neuroscience 269(6) 753-755 Sep.  2019 Refereed
  • Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder.
    Jung Minyoung;Tu Yiheng;Lang Courtney Amanda;Ortiz Ana;Park Joel;Jorgenson Kristen;Kong Xue-Jun;Kong Jian
    NeuroImage 2017 Refereed
  • Catechol-O-methyltransferase polymorphism is associated with the cortico-cerebellar functional connectivity of executive function in children with attention-deficit/hyperactivity disorder.
    Mizuno Yoshifumi;Jung Minyoung;Fujisawa Takashi X;Takiguchi Shinichiro;Shimada Koji;Saito Daisuke N;Kosaka Hirotaka;Tomoda Akemi
    Scientific reports 7(1) 2017 Refereed
  • Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.
    Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya KJ, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H
    Molecular autism 7 2016 Refereed
  • Altered frontal pole development affects self-generated spatial working memory in ADHD.
    Arai S, Okamoto Y, Fujioka T, Inohara K, Ishitobi M, Matsumura Y, Jung M, Kawamura K, Takiguchi S, Tomoda A, Wada Y, Hiratani M, Matsuura N, Kosaka H
    Brain & development 38(5) 2016 Refereed
  • Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial.
    Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa TX, Tanaka S, Arai S, Asano M, Saito DN, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y
    Translational psychiatry 2016 Refereed
  • Differences in Brain Hemodynamics in Response to Achromatic and Chromatic Cards of the Rorschach: A fMRI Study.
    Ishibashi Masahiro;Uchiumi Chigusa;Jung Minyoung;Aizawa Naoki;Makita Kiyoshi;Nakamura Yugo;Saito Daisuke N
    Rorschachiana 37(1) 2016 Refereed
  • Autistic empathy toward autistic others.
    Komeda H, Kosaka H, Saito DN, Mano Y, Jung M, Fujii T, Yanaka HT, Munesue T, Ishitobi M, Sato M, Okazawa H
    Social cognitive and affective neuroscience 10(2) 2015 Refereed
  • Neural Basis of Psychological Growth following Adverse Experiences: A Resting-State Functional MRI Study.
    Fujisawa TX, Jung M, Kojima M, Saito DN, Kosaka H, Tomoda A
    PloS one 2015 Refereed
  • Ventral striatum dysfunction in children and adolescents with reactive attachment disorder: functional MRI study.
    Takiguchi S, Fujisawa TX, Mizushima S, Saito DN, Okamoto Y, Shimada K, Koizumi M, Kumazaki H, Jung M, Kosaka H, Hiratani M, Ohshima Y, Teicher MH, Tomoda A
    BJPsych open 2015 Refereed
  • Sex Differences in the Default Mode Network with Regard to Autism Spectrum Traits: A Resting State fMRI Study.
    Jung M, Mody M, Saito DN, Tomoda A, Okazawa H, Wada Y, Kosaka H
    PloS one 10(11) 2015 Refereed
  • Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits.
    Jung M, Kosaka H, Saito DN, Ishitobi M, Morita T, Inohara K, Asano M, Arai S, Munesue T, Tomoda A, Wada Y, Sadato N, Okazawa H, Iidaka T
    Molecular autism 2014 Refereed
  • Do Individuals With Autism Spectrum Disorders Help Other People With Autism Spectrum Disorders? An Investigation of Empathy and Helping Motivation in Adults With Autism Spectrum Disorder.
    Komeda H;Kosaka H;Fujioka T;Jung M;Okazawa H
    Frontiers in psychiatry 10 376 Jun.  2019 Refereed
    :Individuals with autism spectrum disorder (ASD) often lack cognitive empathy, so they experience difficulty in empathizing with others. Although deficits in social abilities, such as empathy, have been demonstrated in previous studies, most stimuli used in previous studies were developed for typically developing (TD) individuals. Previous studies have demonstrated that adults with and without ASD display empathetic responses toward similar others. Adults with ASD (n = 22, 7 women and 15 men, mean age = 26.8 years) and intelligence- and age-matched TD adults (n = 20, 8 women and 12 men, mean age = 24.0 years) participated in the study. They were instructed to read 24 stories (12 stories featured protagonists with characteristics of ASD, and the other 12 featured TD protagonists) and respond to the following questions: "How did the protagonist feel?" and "Would you help if the protagonist were in trouble?" After controlling for alexithymia and AQ based on multiple regression analyses, individuals with ASD empathize with other people who have ASD and are motivated to help other people with ASD. Additionally, social skills and attention to detail were associated with decreased helping motivation for story characters with ASD. Social skills among AQ subscales (social skills, attention switching, attention to detail, communication, and imagination) were the most potent predictor of decreased helping motivation. These findings suggest that the reason why individuals with ASD are considered to have limited cognitive empathy and helping motivation could be related to alexithymia and the lack of social skills and attention to detail, which are related to atypical perception.
  • Effects of the Co-occurrence of Anxiety and Attention-Deficit/Hyperactivity Disorder on Intrinsic Functional Network Centrality among Children with Autism Spectrum Disorder.
    Wan Bin;Wang Zengjian;Jung Minyoung;Lu Yanchun;He Haoqiang;Chen Qi;Jin Yu
    Autism research : official journal of the International Society for Autism Research 12(7) Jul.  2019 Refereed
    :Children with autism spectrum disorder (ASD) present with a high co-occurrence of anxiety and attention-deficit/hyperactivity disorder (ADHD). However, it remains unclear how the co-occurrence of anxiety and ADHD in children with ASD alters whole-brain functional networks. Here, we aimed to examine anxiety- and ADHD-related brain network centrality in children with ASD separately and their relationships with ASD symptoms. Clinical anxiety and ADHD levels in children with ASD, aged 6-13 years old, were assessed. Participants were categorized into four groups: ASD only (n = 28), ASD + anxiety (n = 19), ASD + ADHD (n = 25), and ASD + both anxiety and ADHD (n = 28). Subsequently, we compared voxel-wise network degree centrality (DC) among the four groups. We found that: (a) compared with ASD only, children with ASD + anxiety showed higher DC in the left middle temporal gyrus, right lingual gyrus, and left cuneus, and lower DC in the right precuneus; (b) children with ASD + ADHD presented higher DC in the right calcarine and left superior frontal gyrus (SFG) compared with ASD only; (c) children with ASD + both displayed higher DC in the right calcarine and lower centrality in the right middle occipital gyrus compared with ASD only; and (d) across all children with ASD, there was a positive correlation between DC of the right calcarine with nonverbal behavior scores, and DC of the left SFG was negatively correlated with social scores. Our findings suggest that the right calcarine, left SFG, and default mode network nodes play important roles in the co-occurrence of anxiety and ADHD among children with ASD. Autism Res 2019, 12: 1057-1068. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The co-occurrence of anxiety and attention-deficit/hyperactivity disorder (ADHD) has been shown to influence the brain function of children with ASD. In order to gain a better understanding of this, the present study compared degree centrality, the amount of effective brain functional connectivity that reflects the characteristics of brain networks, among four groups: ASD only, ASD + anxiety, ASD + ADHD, and ASD + both anxiety and ADHD. We found that some areas located in the language processing network and primary visual cortex were associated with the co-occurrence of ADHD, and some other areas located in the default mode network were associated with the co-occurrence of both anxiety and ADHD. These findings provide more knowledge about the neural basis underlying behavioral changes related to the co-occurrence of anxiety and ADHD in children with ASD.
  • Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder
    Jung, Minyoung;Tu, Yiheng;Lang, Courtney Amanda;Ortiz, Ana;Park, Joel;Jorgenson, Kristen;Kong, Xue-Jun;Kong, Jian
    NEUROIMAGE 190 205-212 Apr.  2019 Refereed
  • Do Individuals With Autism Spectrum Disorders Help Other People With Autism Spectrum Disorders? An Investigation of Empathy and Helping Motivation in Adults With Autism Spectrum Disorder
    Komeda, Hidetsugu;Kosaka, Hirotaka;Fujioka, Toru;Jung, Minyoung;Okazawa, Hidehiko
    FRONTIERS IN PSYCHIATRY 10 Jun.  2019
  • Surface-based shared and distinct resting functional connectivity in attention-deficit hyperactivity disorder and autism spectrum disorder
    Jung, Minyoung;Tu, Yiheng;Park, Joel;Jorgenson, Kristen;Lang, Courtney;Song, Wenwen;Kong, Jian
    BRITISH JOURNAL OF PSYCHIATRY 214(6) 339-344 Jun.  2019
  • Effects of the Co-occurrence of Anxiety and Attention-Deficit/Hyperactivity Disorder on Intrinsic Functional Network Centrality among Children with Autism Spectrum Disorder
    Bin Wan;Wang, Zengjian;Jung, Minyoung;Lu, Yanchun;He, Haoqiang;Chen, Qi;Jin, Yu
    AUTISM RESEARCH 12(7) 1057-1068 Jul.  2019
  • Symptoms in individuals with adult-onset ADHD are masked during childhood
    Kosaka, Hirotaka;Fujioka, Toru;Jung, Minyoung
    EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE 269(6) 753-755 Sep.  2019
  • Sex Differences in White Matter Pathways Related to Language Ability
    Jung, Minyoung;Mody, Maria;Fujioka, Toru;Kimura, Yukari;Okazawa, Hidehiko;Kosaka, Hirotaka
    FRONTIERS IN NEUROSCIENCE 13 Aug.  2019

Conference Activities & Talks

  • Structural connectivity and resting-state brain activity of the lateral occipital cortex impact social communication deficit in boys with autism spectrum disorder 
    Jung M, Fujioka T, Kosaka H.
    The 7th World Congress of Asian Psychiatry 2019 Feb.  2019
  • Developmental changes of attention to social information in Autistic Spectrum Disorder from childhood to adolescence.
    Fujioka T, Tsuchiya KJ, Saito M, Sakamoto Y, Nakamura K, Choi D, Mizuno Y, Takiguchi S, TFujisawa TX, Jung M, Matsuzaki H, Tomoda A, Okato A, Hirano Y, Sasaki T, Yoshida T, Matsuo M, Saito DN, Kikuchi M, Maegaki Y, Katayama T, Kosaka H.
    The 7th World Congress of Asian Psychiatry 2019 Feb.  2019
  • Machine learning and imaging genetics approach to ADHD
    Jung M, Mizuno Y, Fujisawa TX, Takiguchi S, Kosaka H, Tomoda A.
    The 7th World Congress of Asian Psychiatry 2019 Feb.  2019
  • Structural connectivity and resting-state brain activity of the lateral occipital cortex impact social communication deficit in boys with autism spectrum disorder
    Jung M, Kosaka H, Kong J.
    International Autism Conference Tokyo 2017 Oct.  2017
  • Surfaced based shared and distinct resting functional connectivity between attention-deficit/hyperactivity disorder and autism spectrum disorder
    Jung M, Kosaka H, Kong J.
    International Autism Conference Tokyo 2017 Oct.  2017
  • Brain science approach for Autism spectrum disorder.
    Jung M, Kong J, Kosaka H
    2019 Spring KSSE Conference Jun.  2019

Awards & Honors

  •  International Meeting for Autism Research Travel Award2015
  •  日本脳科学会 日本脳科学会奨励賞2014
  •  Daegu University Daegu university 総長賞2009