丁 ミンヨン

所属部署名情動認知発達研究部門
教員組織情動認知発達研究部門
教育研究組織子どものこころの発達研究センター
職名特命講師
更新日: 19/11/28 16:13

研究者基本情報

氏名

    丁 ミンヨン
    ジョン ミンヨン
    Jung Minyoung

基本情報

所属

  •  情動認知発達研究部門 特命講師
  •  情動認知発達研究部門 特命助教

学歴

  • 2013年04月- 2015年03月大阪大学 小児発達
  • 2011年04月- 2013年03月筑波大学 障害科学
  • 2004年03月- 2009年02月Daegu Univiersity (Korea)

学位

  • 障害科学
  • 小児発達学

経歴

  • 2015年08月- 2017年08月米ハ-バ-ド大学 Department of Psychiatry (Massachusetts General Hospital) 研究員
  • 2015年04月- 2016年03月日本学術振興会 特別研究員 PD
  • 2014年04月- 2015年03月日本学術振興会 特別研究員 DC2

研究活動情報

論文

  • The Dysfunction of the Cerebellum and Its Cerebellum-Reward-Sensorimotor Loops in Chronic Spontaneous Urticaria.
    Wang Y, Fang J, Song P, Bao Y, Song W, Liu J, Lang C, Jorgenson K, Jung M, Shen D, Li S, Sun R, Ding X, Yang J, Meng X, Wang N, Yan Z, Yan Y, Kong Q, Dong Y, Cui F, Tu Y, Cui B, Kong J.
    Cerebellum 17(5) 507-516 2018年10月 査読有り
  • Surface-based shared and distinct resting functional connectivity in attention-deficit hyperactivity disorder and autism spectrum disorder
    Jung Minyoung;Tu Yiheng; Park Joel; Jorgenson Kristen; Lang Courtney; Song Wenwen; Kong Jian
    The British Journal of Psychiatry 2019年06月 査読有り
  • The Effects of COMT Polymorphism on Cortical Thickness and Surface Area Abnormalities in Children with ADHD.
    Jung Minyoung;Mizuno Yoshifumi;Fujisawa Takashi X;Takiguchi Shinichiro;Kong Jian;Kosaka Hirotaka;Tomoda Akemi
    Cerebral cortex 2018年12月 査読有り
  • Symptoms in individuals with adult-onset ADHD are masked during childhood.
    Kosaka Hirotaka;Fujioka Toru;Jung Minyoung
    European archives of psychiatry and clinical neuroscience 269(6) 753-755 2019年09月 査読有り
    Kosaka Hirotaka
  • The Dysfunction of the Cerebellum and Its Cerebellum-Reward-Sensorimotor Loops in Chronic Spontaneous Urticaria.
    Wang Yuming;Fang Jiliang;Song Ping;Bao Yan;Song Wenwen;Liu Jiao;Lang Courtney;Jorgenson Kristen;Jung Minyoung;Shen Dong;Li Shasha;Sun Ruirui;Ding Xu;Yang Jiao;Meng Xiao;Wang Ning;Yan Zhifang;Yan Yuhe;Kong Qian;Dong Ying;Cui Fangyuan;Tu Yiheng;Cui Bingnan;Kong Jian
    Cerebellum 17(5) 507-516 2018年10月 査読有り
  • Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder.
    Jung Minyoung;Tu Yiheng;Lang Courtney Amanda;Ortiz Ana;Park Joel;Jorgenson Kristen;Kong Xue-Jun;Kong Jian
    NeuroImage 2017年 査読有り
  • Catechol-O-methyltransferase polymorphism is associated with the cortico-cerebellar functional connectivity of executive function in children with attention-deficit/hyperactivity disorder.
    Mizuno Yoshifumi;Jung Minyoung;Fujisawa Takashi X;Takiguchi Shinichiro;Shimada Koji;Saito Daisuke N;Kosaka Hirotaka;Tomoda Akemi
    Scientific reports 7(1) 2017年 査読有り
  • Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.
    Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya KJ, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H
    Molecular autism 7 2016年 査読有り
  • Altered frontal pole development affects self-generated spatial working memory in ADHD.
    Arai S, Okamoto Y, Fujioka T, Inohara K, Ishitobi M, Matsumura Y, Jung M, Kawamura K, Takiguchi S, Tomoda A, Wada Y, Hiratani M, Matsuura N, Kosaka H
    Brain & development 38(5) 2016年 査読有り
  • Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial.
    Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa TX, Tanaka S, Arai S, Asano M, Saito DN, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y
    Translational psychiatry 2016年 査読有り
  • Differences in Brain Hemodynamics in Response to Achromatic and Chromatic Cards of the Rorschach: A fMRI Study.
    Ishibashi Masahiro;Uchiumi Chigusa;Jung Minyoung;Aizawa Naoki;Makita Kiyoshi;Nakamura Yugo;Saito Daisuke N
    Rorschachiana 37(1) 2016年 査読有り
  • Autistic empathy toward autistic others.
    Komeda H, Kosaka H, Saito DN, Mano Y, Jung M, Fujii T, Yanaka HT, Munesue T, Ishitobi M, Sato M, Okazawa H
    Social cognitive and affective neuroscience 10(2) 2015年 査読有り
  • Neural Basis of Psychological Growth following Adverse Experiences: A Resting-State Functional MRI Study.
    Fujisawa TX, Jung M, Kojima M, Saito DN, Kosaka H, Tomoda A
    PloS one 2015年 査読有り
  • Ventral striatum dysfunction in children and adolescents with reactive attachment disorder: functional MRI study.
    Takiguchi S, Fujisawa TX, Mizushima S, Saito DN, Okamoto Y, Shimada K, Koizumi M, Kumazaki H, Jung M, Kosaka H, Hiratani M, Ohshima Y, Teicher MH, Tomoda A
    BJPsych open 2015年 査読有り
  • Sex Differences in the Default Mode Network with Regard to Autism Spectrum Traits: A Resting State fMRI Study.
    Jung M, Mody M, Saito DN, Tomoda A, Okazawa H, Wada Y, Kosaka H
    PloS one 10(11) 2015年 査読有り
  • Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits.
    Jung M, Kosaka H, Saito DN, Ishitobi M, Morita T, Inohara K, Asano M, Arai S, Munesue T, Tomoda A, Wada Y, Sadato N, Okazawa H, Iidaka T
    Molecular autism 2014年 査読有り
  • Do Individuals With Autism Spectrum Disorders Help Other People With Autism Spectrum Disorders? An Investigation of Empathy and Helping Motivation in Adults With Autism Spectrum Disorder.
    Komeda Hidetsugu;Kosaka Hirotaka;Fujioka Toru;Jung Minyoung;Okazawa Hidehiko
    Frontiers in psychiatry 10 2019年
    :Individuals with autism spectrum disorder (ASD) often lack cognitive empathy, so they experience difficulty in empathizing with others. Although deficits in social abilities, such as empathy, have been demonstrated in previous studies, most stimuli used in previous studies were developed for typically developing (TD) individuals. Previous studies have demonstrated that adults with and without ASD display empathetic responses toward similar others. Adults with ASD (n = 22, 7 women and 15 men, mean age = 26.8 years) and intelligence- and age-matched TD adults (n = 20, 8 women and 12 men, mean age = 24.0 years) participated in the study. They were instructed to read 24 stories (12 stories featured protagonists with characteristics of ASD, and the other 12 featured TD protagonists) and respond to the following questions: "How did the protagonist feel?" and "Would you help if the protagonist were in trouble?" After controlling for alexithymia and AQ based on multiple regression analyses, individuals with ASD empathize with other people who have ASD and are motivated to help other people with ASD. Additionally, social skills and attention to detail were associated with decreased helping motivation for story characters with ASD. Social skills among AQ subscales (social skills, attention switching, attention to detail, communication, and imagination) were the most potent predictor of decreased helping motivation. These findings suggest that the reason why individuals with ASD are considered to have limited cognitive empathy and helping motivation could be related to alexithymia and the lack of social skills and attention to detail, which are related to atypical perception.
  • Effects of the Co-occurrence of Anxiety and Attention-Deficit/Hyperactivity Disorder on Intrinsic Functional Network Centrality among Children with Autism Spectrum Disorder.
    Wan Bin;Wang Zengjian;Jung Minyoung;Lu Yanchun;He Haoqiang;Chen Qi;Jin Yu
    Autism research : official journal of the International Society for Autism Research 12(7) 2019年
    :Children with autism spectrum disorder (ASD) present with a high co-occurrence of anxiety and attention-deficit/hyperactivity disorder (ADHD). However, it remains unclear how the co-occurrence of anxiety and ADHD in children with ASD alters whole-brain functional networks. Here, we aimed to examine anxiety- and ADHD-related brain network centrality in children with ASD separately and their relationships with ASD symptoms. Clinical anxiety and ADHD levels in children with ASD, aged 6-13 years old, were assessed. Participants were categorized into four groups: ASD only (n = 28), ASD + anxiety (n = 19), ASD + ADHD (n = 25), and ASD + both anxiety and ADHD (n = 28). Subsequently, we compared voxel-wise network degree centrality (DC) among the four groups. We found that: (a) compared with ASD only, children with ASD + anxiety showed higher DC in the left middle temporal gyrus, right lingual gyrus, and left cuneus, and lower DC in the right precuneus; (b) children with ASD + ADHD presented higher DC in the right calcarine and left superior frontal gyrus (SFG) compared with ASD only; (c) children with ASD + both displayed higher DC in the right calcarine and lower centrality in the right middle occipital gyrus compared with ASD only; and (d) across all children with ASD, there was a positive correlation between DC of the right calcarine with nonverbal behavior scores, and DC of the left SFG was negatively correlated with social scores. Our findings suggest that the right calcarine, left SFG, and default mode network nodes play important roles in the co-occurrence of anxiety and ADHD among children with ASD. Autism Res 2019, 12: 1057-1068. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The co-occurrence of anxiety and attention-deficit/hyperactivity disorder (ADHD) has been shown to influence the brain function of children with ASD. In order to gain a better understanding of this, the present study compared degree centrality, the amount of effective brain functional connectivity that reflects the characteristics of brain networks, among four groups: ASD only, ASD + anxiety, ASD + ADHD, and ASD + both anxiety and ADHD. We found that some areas located in the language processing network and primary visual cortex were associated with the co-occurrence of ADHD, and some other areas located in the default mode network were associated with the co-occurrence of both anxiety and ADHD. These findings provide more knowledge about the neural basis underlying behavioral changes related to the co-occurrence of anxiety and ADHD in children with ASD.
  • Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder
    Jung, Minyoung;Tu, Yiheng;Lang, Courtney Amanda;Ortiz, Ana;Park, Joel;Jorgenson, Kristen;Kong, Xue-Jun;Kong, Jian
    NEUROIMAGE 190 205-212 2019年04月

講演・口頭発表等

  • 自閉スペクトラム症成人における社会的相互関係,社交不安症状,流暢性がコミュニケーション行為に与える影響についての検討
    木村友香理、藤岡徹、丁ミンヨン、小泉径子、小坂浩隆
     2018年10月 選考有り
  • Structural connectivity and resting-state brain activity of the lateral occipital cortex impact social communication deficit in boys with autism spectrum disorder 
    Jung M, Fujioka T, Kosaka H.
    The 7th World Congress of Asian Psychiatry 2019 2019年02月 選考有り
  • Developmental changes of attention to social information in Autistic Spectrum Disorder from childhood to adolescence.
    Fujioka T, Tsuchiya KJ, Saito M, Sakamoto Y, Nakamura K, Choi D, Mizuno Y, Takiguchi S, TFujisawa TX, Jung M, Matsuzaki H, Tomoda A, Okato A, Hirano Y, Sasaki T, Yoshida T, Matsuo M, Saito DN, Kikuchi M, Maegaki Y, Katayama T, Kosaka H.
    The 7th World Congress of Asian Psychiatry 2019 2019年02月 選考有り
  • Machine learning and imaging genetics approach to ADHD
    Jung M, Mizuno Y, Fujisawa TX, Takiguchi S, Kosaka H, Tomoda A.
    The 7th World Congress of Asian Psychiatry 2019 2019年02月 選考有り
  • Multimodal neuroimaging アプローチにおける自閉症スペクトラム障害の診断補助
    丁ミンヨン、小坂浩隆、Jian Kong
    第58回日本児童青年精神医学会総会 2017年10月
  • ADHD児におけるCOMT遺伝子多型と大脳皮質-小脳の実行機能ネットワークの関連
    水野賀史、丁ミンヨン、藤澤隆史、島田浩二、齋藤大輔、小坂浩隆、友田明美
    第44回日本脳科学会 2017年10月
  • Structural connectivity and resting-state brain activity of the lateral occipital cortex impact social communication deficit in boys with autism spectrum disorder
    Jung M, Kosaka H, Kong J.
    International Autism Conference Tokyo 2017 2017年10月
  • Surfaced based shared and distinct resting functional connectivity between attention-deficit/hyperactivity disorder and autism spectrum disorder
    Jung M, Kosaka H, Kong J.
    International Autism Conference Tokyo 2017 2017年10月

受賞

  •  福井大学医学部 2016年度上半期優秀論文賞2016年
  •  福井大学医学部 2015年度下半期優秀論文賞2016年
  •  福井大学医学部 2014年度後期優秀論文賞2015年
  •  福井大学医学部 2014年度前期優秀論文賞2015年
  •  International Meeting for Autism Research Travel Award2015年
  •  日本脳科学会 日本脳科学会奨励賞2014年
  •  生理学研究所 平成26年度生理研研究会トラベルアワード2014年
  •  Daegu University Daegu university 総長賞2009年

科学研究費補助金

  • 自閉スペクトラム症(ASD)における男女差の原因解明と補助診断への臨床応用若手研究(B)
    代表者:丁 ミンヨン 2018年度
  • 性差における自閉スペクトラム障害(ASD)の神経科学的メカニズムの解明若手研究(B)
    科学研究費補助金
    代表者:丁 ミンヨン 2016年度
  • 神経科学的方法による自閉症スペクトラム障害の情動認識メカニズムの解明
    代表者:丁 ミンヨン 2014年度

教育活動情報

担当授業

  • 大阪大学連合大学院小児発達学 「機能画像解析学2」 (福井大学)
  • 大阪大学連合大学院小児発達学 「機能画像解析学1」 (福井大学)
  • 大阪大学連合大学院小児発達学研究科 「画像生物学演習2」 (福井大学)
  • 大阪大学連合大学院小児発達学研究科 「情動認知発達学特論」 (福井大学)

社会貢献・国際交流活動情報

報道

  • 福井大チーム、AIで解析2018年12月 中日新聞
  • 特定の脳部位に特徴2018年12月 県民福井
  • ADHDの子ども、脳に特徴 福井大学チームがAIで解析2018年12月 福井新聞
  • 自閉症スペクトラム障害2014年09月 読売新聞
  • 自閉症 脳の活動に違い2014年06月 県民福井
  • 自閉症脳の前後連結「弱い」2014年06月 朝日新聞
  • 脳活動連携に弱さ2014年06月 福井新聞
  • 特定の脳部位に特徴 注意欠陥多動性障害の子 AI解析 福井大教授ら発見2018年12月 県民、中日、福井
  • ADHDの脳 特徴発見 MRIで検査5分 子どもの負担軽減 福井大2018年12月 日刊工業
  • ADHD児 高頻度で脳特定部位に特徴 AI活用で解明 福井大が成果2018年12月 科学